Hearing Loss and Hypertension: A Literature Review

Umashankar, Abishek; Prabhu, Prashanth

doi:10.1007/s12070-021-02378-2

Cited by 5 publications

(4 citation statements)

References 21 publications

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“…Arterial stiffness is a crucial risk factor for adverse cardiovascular outcomes [ 28 – 30 ], which can lead to coronary artery disease (e.g., atherosclerosis) and hypertension [ 31 – 34 ]; atherosclerosis and hypertension are widely recognized as key risk factors for ARHL [ 35 – 37 ]. A possible explanation for this phenomenon is that the variants of SNPs (rs1152781 and rs1152783) alter BCL11B expression, thereby further modifying the biological function of BCL11B [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

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Association between BCL11B gene polymorphisms and age-related hearing loss in the elderly: A case-control study in Qingdao, China

Li,

Zhang,

Zhang

et al. 2024

PLoS ONE

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Age-related hearing loss is a complex disease caused by a combination of genetic and environmental factors, and a study have conducted animal experiments to explore the association between BCL11B heterozygosity and age-related hearing loss. The present study used established genetic models to examine the association between BCL11B gene polymorphisms and age-related hearing loss. A total of 410 older adults from two communities in Qingdao, China, participated in this study. The case group comprised individuals aged ≥ 60 years with age-related hearing loss, and the control group comprised individuals without age-related hearing loss from the same communities. The groups were matched 1:1 for age and sex. The individual characteristics of the participants were analyzed descriptively using the Mann–Whitney U test and the chi-square test. To explore the association between BCL11B gene polymorphisms and age-related hearing loss, conditional logistic regression was performed to construct genetic models for two single-nucleotide-polymorphisms (SNPs) of BCL11B, and haplotype analysis was conducted to construct their haplotype domains. Two SNP sites of the BCL11B gene, four genetic models of rs1152781 (additive, dominant, recessive, and codominant), and five genetic models of rs1152783 (additive, dominant, recessive, codominant, and over dominant) were significantly associated with age-related hearing loss in the models both unadjusted and adjusted for all covariates (P < 0.05). Additionally, a linkage disequilibrium between rs1152781 and rs1152783 was revealed through haplotype analysis. Our study revealed that BCL11B gene polymorphisms were significantly associated with age-related hearing loss.

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Section: Discussionmentioning

confidence: 99%

“…atherosclerosis and hypertension are widely recognized as key risk factors for ARHL [35][36][37]. A possible explanation for this phenomenon is that the variants of SNPs (rs1152781 and rs1152783) alter BCL11B expression, thereby further modifying the biological function of BCL11B [11].…”

Section: Plos Onementioning

confidence: 99%

Association between BCL11B gene polymorphisms and age-related hearing loss in the elderly: A case-control study in Qingdao, China

Li,

Zhang,

Zhang

et al. 2024

PLoS ONE

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“…Hypertension is a condition where there is an increase in blood pressure above 130/90 mmHg which can result in increased morbidity and mortality in hypertension sufferers. [2] Based on data from the World Health Organization (WHO), the prevalence of hypertension in the world occurs in population aged > 18 years reaching 1 billion people, the number of sufferers Hypertension is predicted to continue to increase along with population which will increase by 2025, is estimated to be around 29% of the world's citizens affected by hypertension. The African region holds the peak position for hypertension sufferers, namely 40%.…”

Section: Introductionmentioning

confidence: 99%

Medication Adherence and Physical Activity in Relation to Blood Pressure in Hypertension Patients

Mahendra Mardaningrat,

Wiguna,

Lestari

et al. 2023

Int Jou of PHE

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In the 21st century, it is estimated that there will be a rapid increase in the incidence and prevalence of NCDs. It is estimated that the countries that will feel the impact the most are developing countries, including Indonesia. One of the NCDs that is currently a very serious health problem is hypertension. This study aims to determine the relationship between medication adherence and physical activity on blood pressure in hypertension patients. This research is an analytical study with a cross-sectional design. Data collection was carried out by conducting interviews with patients, filling out questionnaires by the patient, viewing the patient's medical record data and carrying out blood pressure checks in September 2023 to October 2023. Bivariate analysis showed that there was an influence of medication attendance (p value = 0.0001; PR = 7.667) and physical activity (p value = 0.0001; PR = 26.156) on blood pressure. Multivariate analysis showed that physical activity (p value = 0.0001; aPR = 23.726) had more influence on blood pressure than medication adherence (p value = 0.007; aPR = 6.622). It is important for health workers to always educate patients regarding medication compliance and increase physical activity in an effort to achieve normal blood pressure.

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“…Hypertension corresponds to a permanently raised blood pressure in arteries and arterioles [ 1 ]. It is defined as a systolic blood pressure equal or above 140 mmHg and /or a diastolic blood pressure above 90 mmHg [ 1 , 2 ]. Hypertension is a threat to global public health [ 3 ] as it tires vessels, the heart and causes damage to artery walls [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi

et al. 2021

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Introduction Hypertension is a major threat to public health globally. Especially in sub-Saharan African countries, this coexists with high burden of other infectious diseases, creating a complex public health situation which is difficult to address. Tackling this will require targeted public health intervention based on evidence that well defines the at risk population. In this study, using retrospective data from two referral hospitals in Burundi, we model the risk factors of hypertension in Burundi. Materials and methods Retrospective data of a sample of 353 randomly selected from a population of 4,380 patients admitted in 2019 in two referral hospitals in Burundi: Military and University teaching hospital of Kamenge. The predictive risk factors were carried out by fixed effect logistic regression. Model performance was assessed with Area under Curve (AUC) method. Model was internally validated using bootstrapping method with 2000 replications. Both data processing and data analysis were done using R software. Results Overall, 16.7% of the patients were found to be hypertensive. This study didn’t showed any significant difference of hypertension’s prevalences among women (16%) and men (17.7%). After adjustment of the model for cofounding covariates, associated risk factors found were advanced age (40–59 years) and above 60 years, high education level, chronic kidney failure, high body mass index, familial history of hypertension. In absence of these highlighted risk factors, the risk of hypertension occurrence was about 2 per 1000 persons. This probability is more than 90% in patients with more than three risk factors. Conclusion The relatively high prevalence and associated risk factors of hypertension in Burundi raises a call for concern especially in this context where there exist an equally high burden of infectious diseases, other chronic diseases including chronic malnutrition. Targeting interventions based on these identified risk factors will allow judicious channel of resources and effective public health planning.

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Hearing Loss and Hypertension: A Literature Review

Cited by 5 publications

References 21 publications

Association between BCL11B gene polymorphisms and age-related hearing loss in the elderly: A case-control study in Qingdao, China

Association between BCL11B gene polymorphisms and age-related hearing loss in the elderly: A case-control study in Qingdao, China

Medication Adherence and Physical Activity in Relation to Blood Pressure in Hypertension Patients

Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi

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