Hearing loss and tinnitus in Meniere's disease

Havia, Mari; Kentala, Erna; Pyykkö, Ilmari

doi:10.1016/s0385-8146(01)00142-0

Cited by 50 publications

(43 citation statements)

References 13 publications

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“…The mechanisms underlying tinnitus are not completely understood, however some literature suggest this condition is usually accompanied by low-frequency loss (Havia et al, 2002) whilst others suggest high-frequency loss (Martines et al, 2010). Our modelling does show an interaction between frequency and tinnitus; study participants reporting tinnitus had greater hearing thresholds at the higher frequencies (4, 6 and 8 kHz).…”

Section: Tinnitusmentioning

confidence: 50%

Relative risk of elevated hearing threshold compared to ISO1999 normative populations for Royal Australian Air Force male personnel

Guest¹,

Boggess²,

Attia³

2012

Hearing Research

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Section: Tinnitusmentioning

confidence: 50%

Relative risk of elevated hearing threshold compared to ISO1999 normative populations for Royal Australian Air Force male personnel

Guest¹,

Boggess²,

Attia³

2012

Hearing Research

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“…Time to conversion of unilateral bilateral disease also varies from one study to another. All authors agree that there are cases in which MD presents with a bilateral symptomatology from onset [Green et al, 1991;Havia et al, 2002;Havia and Kentala, 2004]. However, in most cases, involvement of the second ear appears only as disease progresses.…”

Section: Time Interval To the Involvement Of The Contralateral Ear Inmentioning

confidence: 84%

“…We found few isolated cases of conversion to bilaterality after the 7th year of disease. Moreover, the evolution of vertigo is more difficult to predict in bilateral cases since patients, depending on the moment at which they develop bilateral involvement, will suffer from vertiginous crises arising either from both ears or from one of them first and then from the other, in contrast to the results published by Havia et al [2002] and Havia and Kentala [2004]. Furthermore, hearing loss caused by involvement of both ears induces greater disability and has more severe consequences for already affected patients.…”

Section: Time Interval To the Involvement Of The Contralateral Ear Inmentioning

confidence: 93%

“…However, in most cases, involvement of the second ear appears only as disease progresses. All authors also agree that the longer the duration of the disease, the greater the percentage of bilaterality [Morrison, 1975;Charachon, 1989;Stahle and Bergman, 1967;Thomas and Harrison, 1971;Green et al, 1991;Havia et al, 2002;Havia and Kentala, 2004]. Most authors, with the exception of Morrison [1975], have come to the conclusion that involvement of both ears usually occurs within a short period of time, i.e.…”

Section: Time Interval To the Involvement Of The Contralateral Ear Inmentioning

confidence: 99%

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Evolution of Symptoms in Ménière’s Disease

Belinchon

Pérez-Garrigues

Tenias³

2011

Audiol Neurotol

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Objective: To investigate the sequence and correlation of symptoms of Ménière’s disease (MD) depending on their order of manifestation. Methods: Descriptive, longitudinal study of the symptoms in 237 tertiary hospital patients who had been diagnosed with definite MD according to the criteria of the American Academy of Otolaryngology. Patients were followed for 1–31 years. Results: Disease began with the three classic symptoms in only 40% of the patients. We recorded the mean, median and maximum time needed to complete the symptoms as well as the time elapsed in some patients from disease onset in one ear to bilateral involvement. Conclusions: We reckon that this study may be of great help in ruling out a diagnosis of MD when the patient presents with only one or two symptoms of the triad. Furthermore, regarding the planning of treatment, the time interval between unilateral and bilateral involvement (5–7 years) is very important since bilateral involvement has great repercussions on treatment, especially surgical treatment.

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“…Tinnitus severity was assessed on 5-point scale from none to very severe tinnitus and the patients were followed for two years (56). The authors used a larger group of patients with Menière's disease as controls (57). Compared with the pretreatment period the mean scores of patients were lower and showed significant reduction of tinnitus severity.…”

Section: Treatment Of Tinnitus In Menière's Disease With Gentamicinmentioning

confidence: 99%

Tinnitus treatment: Are drugs effective?

Pyykkö

Zou

Kentala

et al. 2008

Audiological Medicine

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This work evaluates trials on drug treatment of tinnitus. Tinnitus is a subjective complaint and there are no objective outcome measures. The rationale of treating tinnitus is based on two major therapeutic models: 1) cochlear origin of tinnitus in that tinnitus is alleviated by cochlear mechanisms reducing the cytotoxicity induced by the metabolic stress, influencing neural transmission and restoring the cochlear homeostasis. 2) central origin of tinnitus that involves similar mechanisms to neuropathic pain. In controlled studies there are no convincing results that any treatment will be beneficial for tinnitus. There are some exceptions with drugs that antagonize neurotransmission in glutaminergic receptors, and also possibly melatonin when sleep disorders are associated with tinnitus. The central neurotransmitter agonists and antagonists seem not to be effective. Finally, novel nano-technological advances in targeted drug carrier technology that can administer growth factors and gene machinery may be useful in future treatment of tinnitus.

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Hearing loss and tinnitus in Meniere's disease

Cited by 50 publications

References 13 publications

Relative risk of elevated hearing threshold compared to ISO1999 normative populations for Royal Australian Air Force male personnel

Relative risk of elevated hearing threshold compared to ISO1999 normative populations for Royal Australian Air Force male personnel

Evolution of Symptoms in Ménière’s Disease

Tinnitus treatment: Are drugs effective?

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