Hearing loss in pregnancy

Murthy, V. Ashok; Krishna, Kirtan

doi:10.1007/s12070-011-0329-0

Cited by 8 publications

(7 citation statements)

References 8 publications

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“…Estrogen and progesterone are the chief pregnancy hormones. The increased level of sex hormones during pregnancy has been suggested to interrupt cochlear circulation and elicit cochlear fluid imbalance, leading to SSNHL . In opposition to this potential mechanism, estrogen has been shown to exert a protective effect on hearing .…”

Section: Discussionmentioning

confidence: 99%

Pregnancy Does Not Increase the Risk of Sudden Sensorineural Hearing Loss: A National Cohort Study

Lee

Kong

et al. 2019

The Laryngoscope

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Objectives/Hypothesis Pregnancy‐induced systemic physiological changes appear to be associated with reversible hearing changes in pregnant/postpartum women. However, most studies are case reports due to the rare occurrence of sudden sensorineural hearing loss (SSNHL) during pregnancy. We aimed to evaluate the risk of SSNHL during the pregnancy and postpartum periods. Study Design A longitudinal case‐control study using a nationwide population cohort. Methods Using the Korean National Health Insurance Review and Assessment Service, we collected data from 63,331 pregnant/postpartum participants who were matched 1:2 by age, income, region of residence, and medical history with 126,662 control participants. We included participants who had International Classification of Diseases, 10th Revision (ICD‐10) codes indicating delivery (O80–O84). For SSNHL (ICD‐10 code H91.2), we included only those participants who underwent audiometry and were treated with steroids. The incidence of SSNHL was measured for the periods corresponding to pregnancy (conception through delivery) up to 1 year postpartum in the pregnant participants. Results During the pregnancy period, the SSNHL rate was not higher (19.5 per 100,000) compared with the control group (60.7 per 100,000). The adjusted odds ratio of SSNHL during pregnancy was 0.32 (95% confidence interval: 0.16‐0.65, P = .002). The SSNHL rate during the postpartum period (37.9 per 100,000) was similar to that of the control group (36.3 per 100,000). The adjusted odds ratio of SSNHL during the postpartum period was 1.04 (95% confidence interval: 0.64‐1.71, P = .867). The risk of SSNHL in the patients during the pregnancy/postpartum period was not higher than that in controls, regardless of age and specific subperiod. Conclusions The pregnant and postpartum women were not at higher risk of SSNHL. Level of Evidence NA Laryngoscope, 130:E237–E242, 2020

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Section: Discussionmentioning

confidence: 99%

Pregnancy Does Not Increase the Risk of Sudden Sensorineural Hearing Loss: A National Cohort Study

Lee

Kong

et al. 2019

The Laryngoscope

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“…However, this elevation tends to remain within normal clinical levels. In addition to changes in hearing sensitivity, reduction in DPOAE have been found with DPOAE being absent in 26% of the pregnant as opposed to 4% of the non-pregnant women (Ashok Murthy and Krishna, 2013).…”

Section: Pregnancymentioning

confidence: 99%

Sex differences and the effect of female sex hormones on auditory function: a systematic review

Aloufi

Heinrich

Marshall

et al. 2023

Front. Hum. Neurosci.

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AimsFirst, to discuss sex differences in auditory function between women and men, and whether cyclic fluctuations in levels of female sex hormones (i.e., estradiol and progesterone) affect auditory function in pre-menopausal and post-menopausal women. Second, to systematically review the literature concerning the discussed patterns in order to give an overview of the methodologies used in research. Last, to identify the gap in knowledge and to make recommendations for future work.Methods for the systematic reviewPopulation, Exposure, Control, Outcome and Study design (PECOS) criteria were used in developing the review questions. The review protocol follows the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and was pre-registered in the Prospective Register of Systematic Reviews (PROSPERO; CRD42020201480). Data Sources: EMBASE, PubMed, MEDLINE (Ovid), PsycINFO, ComDisDome, CINAHL, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL) via Cochrane Library, and scanning reference lists of relevant studies, and internet resources (i.e., Mendeley) were used. Only studies published between 1999 and 2022, in English, or in English translation, were included. The quality of evidence was assessed using the Newcastle-Ottawa Scale (NOS).ResultsSex differences: Women had more sensitive hearing (measured at the level of peripheral and central auditory system) than men. Cyclic fluctuations: Auditory function in women fluctuated during the menstrual cycle, while no such fluctuations in men over the same time period were reported. Hearing sensitivity improved in women during the late follicular phase, and decrease during the luteal phase, implying an effect of female sex hormones, although the specific effects of estradiol and progesterone fluctuations on the central auditory system remain unclear. Hearing sensitivity in women declined rapidly at the onset of menopause.ConclusionThe review has shown the following. Consistent sex differences exist in auditory function across the auditory pathway with pre-menopausal women often showing better function than age-matched men. Moreover, pre-menopausal women show fluctuations in hearing function across the menstrual cycle with a better function during the peak of estradiol or when the ratio of estradiol to progesterone is high. Third, menopause marks the onset of hearing loss in women, characterized by a rapid decline in hearing sensitivity and a more pronounced loss than in age-matched men. Finally, the systematic review highlights the need for well-designed and -controlled studies to evaluate the influence of estradiol and progesterone on hearing by consistently including control groups (e.g., age-matched man), using objective tests to measure hormonal levels (e.g., in saliva or blood), and by testing participants at different points across the menstrual cycle.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020201480, identifier CRD42020201480.

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“…Therefore it remains crucial for otorhinolaryngologists to assess and manage these complications, providing reassurance to those patients. Moreover, medical practitioners and gynecologists should be prepared to anticipate and address these manifestations to offer reassurance and ensure the safe management of such symptoms [1,3,13].…”

Section: Introductionmentioning

confidence: 99%

Objective Measurements of Nasal Obstruction and Eustachian Tube Function in Pregnant Women

Grajczyk,

Sobczyk,

Zarzecka

et al. 2024

JCM

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Background: Hormonal changes during pregnancy have a substantial effect on the swelling of the mucous membrane in the nasal cavity, resulting in rhinitis and Eustachian tube dysfunction. The aim of the study was to assess subjective and objective changes in nasal cavity and Eustachian tube patency in the third trimester of pregnancy. Materials and Methods: The study group included fifty 18–41 year-old women in the third trimester of pregnancy. The control group consisted of 25 females aged 25 to 31 who were not pregnant. The Eustachian tube and nasal cavity patency examination was carried out using a rhinomanometer, a tympanometer and a SNOT-22 Questionnaire. Results: The SNOT-22 showed that subjective nasal obstruction was assessed as strong or worse by 42% of the study group, which was significantly higher than in the control group and confirmed with rhinomanometry. A total of 68% of the study group reported a subjective ear fullness which correlated with the week of pregnancy. The tympanometry showed that all pregnant women exhibited a type A tympanogram, but tympanometry values decreased at higher weeks of pregnancy, and statistical analysis confirmed a significant difference between the study group and the control group in tympanometry for both ears. Conclusions: The results highlight the substantial impact on both subjective and objective measurements of nasal and Eustachian tube patency. Almost every woman in the third trimester of pregnancy experiences nasal obstruction, and nearly 70% struggle with ear fullness. Recognizing and addressing these challenges are pivotal for ensuring the well-being of pregnant individuals and enhancing the quality of antenatal care.

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Hearing loss in pregnancy

Cited by 8 publications

References 8 publications

Pregnancy Does Not Increase the Risk of Sudden Sensorineural Hearing Loss: A National Cohort Study

Pregnancy Does Not Increase the Risk of Sudden Sensorineural Hearing Loss: A National Cohort Study

Sex differences and the effect of female sex hormones on auditory function: a systematic review

Objective Measurements of Nasal Obstruction and Eustachian Tube Function in Pregnant Women

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