Hearing loss in sarcoidosis

Majumdar, Bishakha; Crowther, John A.

doi:10.1017/s0022215100094731

Cited by 16 publications

(8 citation statements)

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“…Recovery of hearing is unpredictable, however, and was only 40% in one small series [23]. In the two previously described pediatric patients with hearing loss from sarcoidosis, one had lymphadenopathy, uveitis, and only a moderate improvement in hearing with prednisone therapy, and the other had parotid swelling, lymphadenopathy, uveitis, and no improvement in hearing [4,5].…”

Section: Discussionmentioning

confidence: 95%

“…Hearing loss is an unusual presenting feature of sarcoidosis, with only two pediatric patients described in the literature and neither with renal involvement [4,5]. In this report, we present a 14-year-old boy without typical pulmonary findings and with a unique presentation of acute deafness and granulomatous interstitial nephritis leading to the likely diagnosis of sarcoidosis.…”

Section: Introductionmentioning

confidence: 85%

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Sarcoidosis presenting with hearing loss and granulomatous interstitial nephritis in an adolescent

et al. 2006

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Granulomatous interstitial nephritis is an uncommon finding in a kidney biopsy. The differential diagnosis is broad and includes infections, drug exposure, and sarcoidosis. Sarcoidosis, a systemic disorder of unknown etiology characterized by the presence of noncaseating granulomata in affected organs, is rare in children. We discuss an adolescent boy with the unusual presentation of granulomatous interstitial nephritis and acute deafness. Sarcoidosis should be considered as part of the differential diagnosis for children and adolescents with hearing loss and kidney disease.

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Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 85%

Sarcoidosis presenting with hearing loss and granulomatous interstitial nephritis in an adolescent

et al. 2006

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“…Case 1 presented with aural fullness and bilateral symmetric hearing loss in conjunction with parotid enlargement, both of which were treated successfully by oral steroids. In Majumdar and Crowther's review of 35 cases of deafness attributed to sarcoidosis, they found that only 26 had histologically confirmed sarcoidosis ( 6 ). In 40% of these, there was no other neurological involvement; in 43% of cases however, a facial nerve palsy was evident.…”

Section: Discussionmentioning

confidence: 99%

“…It can be both central and peripheral ( 2 ). Vertigo is variably present but caloric responses are usually absent, even in the absence of vestibular symptoms ( 6 ). Our case 6 showed peripheral vestibulopathy, with ABR prolongation (Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Evaluation of the patient with NOS requires clinically relevant studies for management, such as calorics, audio, electronystagmography (ENG), and MRI ( 5 ). Suspicion that sarcoidosis is the cause of a statoacoustic disorder should be heightened when a facial or other cranial neuropathy with uveitis, granulomatous meningitis, or diabetes insipidus accompanies the otologic condition ( 7 ) In these cases, a(CXR) would be considered an important part of the initial evaluation ( 6 ) along with ACE level, RPR, and perhaps HIV testing because of the inaccessibility of the region to biopsy for tissue diagnosis. ABR and VEP may provide useful information regarding the subclinical deficits present in cranial nerves.…”

Section: Discussionmentioning

confidence: 99%

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Otolaryngologic Manifestations of Sarcoidosis: Presentation and Diagnosis

et al. 1997

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Neuro-otologic manifestations of sarcoidosis are rare. Dizziness in particular is a rare presenting complaint of the patient afflicted with this systemic granulomatous disorder. Head and neck and sinonasal presentations of this disease are more common. We reviewed our experience with six such patients who presented for management of their otolaryngologic (ORL) manifestations in order to delineate the involvement of the otolaryngologist in the treatment and diagnosis of these patients, with a focus upon the relevant tests and procedures in the otolaryngologist's de novo diagnosis of sarcoidosis. Studies ordered in the course of otolaryngologic evaluation and their utility in the diagnosis of sarcoidosis by the otolaryngologist are reviewed and classified into useful, supportive, and ancillary. The otolaryngologist played an important role in diagnosis, with four of six patients diagnosed to have sarcoidosis on the basis of their otolaryngologic presentations. Biopsy was performed by the otolaryngologist for diagnosis of sarcoidosis in all four of these cases. Steroids were central to treatment. Oral steroid therapy was the principal treatment: both patients with neuro-otologic sarcoid were successfully managed with oral steroids. Intralesional steroids were necessary to treat the skin lesion. One of six patients patients experienced complications related to steroid use.

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Sarcoidosis of the head and neck

Ellison

Canalis

1986

Clinics in Dermatology

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Hearing loss in sarcoidosis

Cited by 16 publications

References 9 publications

Sarcoidosis presenting with hearing loss and granulomatous interstitial nephritis in an adolescent

Sarcoidosis presenting with hearing loss and granulomatous interstitial nephritis in an adolescent

Otolaryngologic Manifestations of Sarcoidosis: Presentation and Diagnosis

Sarcoidosis of the head and neck

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