Hearing Loss in SARS-CoV-2: What Do We Know?

Saniasiaya, Jeyasakthy

doi:10.1177/0145561320946902

Cited by 70 publications

(88 citation statements)

References 14 publications

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“…Many hypotheses have been proposed about the pathophysiology of COVID-19 and the mechanisms that may result in atypical manifestations of the disease [ 13 – 16 ]. Possible etiologies include an impairment in the auditory center in the temporal lobe due to viral pathophysiology mediated by angiotensin-converting enzyme 2 (ACE2), the involvement of the microvasculature of the inner ear or the auditory center, or a peripheral injury (to the hair cells of the cochlea) due to the neurotropism of this virus [ 13 – 15 ].…”

Section: Discussionmentioning

confidence: 99%

A 67-Year-Old Woman with Sudden Hearing Loss Associated with SARS-CoV-2 Infection

Lamounier¹,

Gonçalves²,

Ramos³

et al. 2020

Am J Case Rep

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Patient: Female, 67-year-old Final Diagnosis: SARS-CoV-2 Symptoms: Cough • fever • hearing Loss Medication: — Clinical Procedure: Intensive Care Unit (ICU) Specialty: Otolaryngology Objective: Unusual clinical course Background: Few reports have described the association between coronavirus disease 2019 (COVID-19) and sudden hearing loss. The precise pathophysiological mechanism causing this symptom is unknown. This report describes a case of sudden hearing loss in a patient with COVID-19 pneumonia due to SARS-CoV-2 infection. Case Report: A 67-year-old woman with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as confirmed by reverse transcription-polymerase chain reaction (RT-PCR) testing from nasopharyngeal and oropharyngeal swabs, was examined. She experienced sudden hearing loss in her right ear and disabling tinnitus. She underwent combined corticosteroid therapy (oral and intratympanic), resulting in an isolated improvement of 250 kHz in the right ear (from 60 dB, the threshold became 15 dB) and of 4, 6, and 8 kHz in the left ear (from 35 dB, 20 dB, and 35 dB, the thresholds became 15 dB, 5 dB and 20 dB, respectively). Conclusions: Although rare, hearing loss appears to be a possible sequela to SARS-CoV-2 infection and deserves attention because it is a medical emergency requiring immediate clinical treatment. Additional studies are needed to assess the pathophysiological mechanisms involved in and the long-term characteristics of this type of hearing loss.

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Section: Discussionmentioning

confidence: 99%

A 67-Year-Old Woman with Sudden Hearing Loss Associated with SARS-CoV-2 Infection

Lamounier¹,

Gonçalves²,

Ramos³

et al. 2020

Am J Case Rep

View full text Add to dashboard Cite

show abstract

“…In addition, COVID-19 may lead to cytokine release once it binds to the ACE2. Therefore, the hearing centers may be influenced by the inflammatory mediators released upon binding to the surface receptors in the central auditory nuclei [ [7] , [8] , [9] ]. Another plausible hypothesis of SNHL is ensuing decreased perfusion to the auditory structures due to ischemia.…”

Section: Discussionmentioning

confidence: 99%

Cochlear implant failure following COVID 19: Report of two cases

Saki

Karimi²,

Bayat

2021

American Journal of Otolaryngology

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“…17 Various theories suggesting the possibilities of sensorineural hearing loss have been put forward such as neural inflammation of auditory centers, vasospasm resulting in reduced perfusion to the inner ear, etc. 18 Although not documented in the pediatric population, there are few cases of sudden sensorineural hearing loss that have been reported in adults with SARS CoV-2, however, its etiological role is yet to be established. 19,20 Degen et al have documented cochlear inflammation in MRI of a patient who developed profound hearing loss during the disease.…”

Section: Age and Gender Distributionmentioning

confidence: 99%

Otorhinolaryngological and Ophthalmological Manifestations of COVID-19 in the Pediatric Population

Magar

Gyawali²

2020

J Nepal Med Assoc

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Severe Acute Respiratory Syndrome Coronavirus 2 pandemic has affected several countries throughout the world. Being very contagious, it can affect any individual. So far, the prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 in children amongst the total infected population is very low, ranging from 1-5%. Difficulty in diagnosing the disease clinically in the pediatric population owing to their inability to explain their symptoms often renders a possibility of overlooking this disease. Moreover, new modes of presentation are being reported apart from the classical tell-tale signs. In this scenario, medical professionals dealing with the children should be well aware of different modes of presentation of this disease in the pediatric population. This study thus aims to review otorhinolaryngological and ophthalmological manifestations in the pediatric population affected by Severe Acute Respiratory Syndrome Coronavirus 2.

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Hearing Loss in SARS-CoV-2: What Do We Know?

Cited by 70 publications

References 14 publications

A 67-Year-Old Woman with Sudden Hearing Loss Associated with SARS-CoV-2 Infection

A 67-Year-Old Woman with Sudden Hearing Loss Associated with SARS-CoV-2 Infection

Cochlear implant failure following COVID 19: Report of two cases

Otorhinolaryngological and Ophthalmological Manifestations of COVID-19 in the Pediatric Population

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