Hearing screening for Japanese children and young adults using the automated auditory brainstem response

Soares, Marina Celestino; Nakazawa, Minato; Ishikawa, Kazuo; Sato, Teruyuki; Honda, Kazuo

doi:10.1016/j.anl.2013.08.001

Cited by 7 publications

(12 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Briefly, 10 primary studies were included in this update. 17,[22][23][24][25][26][27][28][29][30] One was published before 2005 24 but was included here as it had been missed by the original 2007 HTA report. 12 The other nine studies were published in the period 2005-2014.…”

Section: Search Results and Selection Of Studiesmentioning

confidence: 99%

“…17,22,23,[25][26][27][28][29][30] Four of them were conducted in China 22,23,27,30 and one in each of the following countries: Brazil, 25 Greece, 29 Japan, 26 Kenya, 24 the Philippines 17 and the USA. 22 (three studies [25][26][27] did not report mean age and only gave age range as an inclusion criterion). The studies were relatively balanced in terms of participants' gender, the proportion of males ranging from 48.4% 26 to 62.5% 30 (two papers 23,28 did not report details).…”

Section: Search Results and Selection Of Studiesmentioning

confidence: 99%

“…Apart from lack of consent, most studies did not specify any other exclusion criteria. One study 26 excluded children who were unable to lie down still for several minutes, which was a necessary requirement for completing the screen procedure; one study 27 excluded children with learning disabilities and two studies 26,30 commented that no children with known cognitive or hearing impairments were included but it was unclear if this had been a prespecified exclusion criterion. Seven studies 17,[22][23][24][25]27,30 were conducted in countries without established UNHS.…”

Section: Search Results and Selection Of Studiesmentioning

confidence: 99%

“…In five studies, 17,24,26,28,30 however, the reference standard was suboptimal and did not meet the quality criterion 'PTA + tympanometry'. The time between the performance of the index test and the reference standard was < 1 month in four studies, 17,22,23,30 was > 1 month in one study 28 and was not reported in five studies.…”

Section: Methodological Quality Of Included Studiesmentioning

confidence: 99%

“…Data-driven selection of a threshold to achieve optimal performance (best sensitivity and/or best specificity) could lead to overly optimistic diagnostic accuracy estimates and the test is likely to perform worse when the same threshold is used in an independent sample of patients. 31 The reference standard was a combination of otoscopy, tympanometry and audiometry in four studies, 22,23,25,29 otoscopy, tympanometry, audiometry and OAEs in one study, 27 ear, nose and throat (ENT) examination including audiometry in two studies, 24,26 and audiometry only in three studies. 17,28,30 The tests were performed by audiologists and otolaryngologists, usually in quiet but not sound-treated rooms with monitored ambient noise.…”

mentioning

confidence: 99%

See 4 more Smart Citations

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

Fortnum

Ukoumunne

Hyde

et al. 2016

Health Technol Assess

View full text Add to dashboard Cite

BackgroundIdentification of permanent hearing impairment at the earliest possible age is crucial to maximise the development of speech and language. Universal newborn hearing screening identifies the majority of the 1 in 1000 children born with a hearing impairment, but later onset can occur at any time and there is no optimum time for further screening. A universal but non-standardised school entry screening (SES) programme is in place in many parts of the UK but its value is questioned.ObjectivesTo evaluate the diagnostic accuracy of hearing screening tests and the cost-effectiveness of the SES programme in the UK.DesignSystematic review, case–control diagnostic accuracy study, comparison of routinely collected data for services with and without a SES programme, parental questionnaires, observation of practical implementation and cost-effectiveness modelling.SettingSecond- and third-tier audiology services; community.ParticipantsChildren aged 4–6 years and their parents.Main outcome measuresDiagnostic accuracy of two hearing screening devices, referral rate and source, yield, age at referral and cost per quality-adjusted life-year.ResultsThe review of diagnostic accuracy studies concluded that research to date demonstrates marked variability in the design, methodological quality and results. The pure-tone screen (PTS) (Amplivox, Eynsham, UK) and HearCheck (HC) screener (Siemens, Frimley, UK) devices had high sensitivity (PTS ≥ 89%, HC ≥ 83%) and specificity (PTS ≥ 78%, HC ≥ 83%) for identifying hearing impairment. The rate of referral for hearing problems was 36% lower with SES (Nottingham) relative to no SES (Cambridge) [rate ratio 0.64, 95% confidence interval (CI) 0.59 to 0.69;p < 0.001]. The yield of confirmed cases did not differ between areas with and without SES (rate ratio 0.82, 95% CI 0.63 to 1.06;p = 0.12). The mean age of referral did not differ between areas with and without SES for all referrals but children with confirmed hearing impairment were older at referral in the site with SES (mean age difference 0.47 years, 95% CI 0.24 to 0.70 years;p < 0.001). Parental responses revealed that the consequences to the family of the referral process are minor. A SES programme is unlikely to be cost-effective and, using base-case assumptions, is dominated by a no screening strategy. A SES programme could be cost-effective if there are fewer referrals associated with SES programmes or if referrals occur more quickly with SES programmes.ConclusionsA SES programme using the PTS or HC screener is unlikely to be effective in increasing the identified number of cases with hearing impairment and lowering the average age at identification and is therefore unlikely to represent good value for money. This finding is, however, critically dependent on the results of the observational study comparing Nottingham and Cambridge, which has limitations. The following are suggested: systematic reviews of the accuracy of devices used to measure hearing at school entry; characterisation and measurement of the cost-effectiveness of different approaches to the ad-hoc referral system; examination of programme specificity as opposed to test specificity; further observational comparative studies of different programmes; and opportunistic trials of withdrawal of SES programmes.Trial registrationCurrent Controlled Trials ISRCTN61668996.FundingThis project was funded by the NIHR Health Technology Assessment programme and will be published in full inHealth Technology Assessment; Vol. 20, No. 36. See the NIHR Journals Library website for further project information.

show abstract

Section: Search Results and Selection Of Studiesmentioning

confidence: 99%

Section: Search Results and Selection Of Studiesmentioning

confidence: 99%

Section: Search Results and Selection Of Studiesmentioning

confidence: 99%

Section: Methodological Quality Of Included Studiesmentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

Fortnum

Ukoumunne

Hyde

et al. 2016

Health Technol Assess

View full text Add to dashboard Cite

show abstract

A directly comparative two-gate case–control diagnostic accuracy study of the pure tone screen and HearCheck screener tests for identifying hearing impairment in school children

et al. 2017

View full text Add to dashboard Cite

ObjectivesThis study directly compared the accuracy of two audiometry-based tests for screening school children for hearing impairment: the currently used test, pure tone screen and a device newly applied to children, HearCheck Screener.DesignTwo-gate case–control diagnostic test accuracy study.Setting and participantsHearing impaired children (‘intended cases’) aged 4–6 years were recruited between February 2013 and August 2014 from collaborating audiology services. Children with no previously identified impairment (‘intended controls’) were recruited from Foundation and Year 1 of schools between February 2013 and June 2014 in central England. The reference standard was pure tone audiometry. Tests were administered at Nottingham Hearing Biomedical Research Unit or, for some intended cases only, in the participant’s home.Main outcome measuresSensitivity and specificity of the pure tone screen and HearCheck tests based on pure tone audiometry result as reference standard.Results315 children (630 ears) were recruited; 75 from audiology services and 240 from schools. Full test and reference standard data were obtained for 600 ears; 155 ears were classified as truly impaired and 445 as truly hearing based on the pure tone audiometry assessment. Sensitivity was estimated to be 94.2% (95% CI 89.0% to 97.0%) for pure tone screen and 89.0% (95% CI 82.9% to 93.1%) for HearCheck (difference=5.2% favouring pure tone screen; 95% CI 0.2% to 10.1%; p=0.02). Estimates for specificity were 82.2% (95% CI 77.7% to 86.0%) for pure tone screen and 86.5% (95% CI 82.5% to 89.8%) for HearCheck (difference=4.3% favouring HearCheck; 95% CI0.4% to 8.2%; p=0.02).ConclusionPure tone screen was better than HearCheck with respect to sensitivity but inferior with respect to specificity. As avoiding missed cases is arguably of greater importance for school entry screening, pure tone screen is probably preferable in this context.Study registration numberCurrent controlled trials: ISRCTN61668996.

show abstract

Axonal Projection Patterns of the Dorsal Interneuron Populations in the Embryonic Hindbrain

et al. 2021

View full text Add to dashboard Cite

Unraveling the inner workings of neural circuits entails understanding the cellular origin and axonal pathfinding of various neuronal groups during development. In the embryonic hindbrain, different subtypes of dorsal interneurons (dINs) evolve along the dorsal-ventral (DV) axis of rhombomeres and are imperative for the assembly of central brainstem circuits. dINs are divided into two classes, class A and class B, each containing four neuronal subgroups (dA1-4 and dB1-4) that are born in well-defined DV positions. While all interneurons belonging to class A express the transcription factor Olig3 and become excitatory, all class B interneurons express the transcription factor Lbx1 but are diverse in their excitatory or inhibitory fate. Moreover, within every class, each interneuron subtype displays its own specification genes and axonal projection patterns which are required to govern the stage-by-stage assembly of their connectivity toward their target sites. Remarkably, despite the similar genetic landmark of each dINs subgroup along the anterior-posterior (AP) axis of the hindbrain, genetic fate maps of some dA/dB neuronal subtypes uncovered their contribution to different nuclei centers in relation to their rhombomeric origin. Thus, DV and AP positional information has to be orchestrated in each dA/dB subpopulation to form distinct neuronal circuits in the hindbrain. Over the span of several decades, different axonal routes have been well-documented to dynamically emerge and grow throughout the hindbrain DV and AP positions. Yet, the genetic link between these distinct axonal bundles and their neuronal origin is not fully clear. In this study, we reviewed the available data regarding the association between the specification of early-born dorsal interneuron subpopulations in the hindbrain and their axonal circuitry development and fate, as well as the present existing knowledge on molecular effectors underlying the process of axonal growth.

show abstract

Hearing screening for Japanese children and young adults using the automated auditory brainstem response

Cited by 7 publications

References 21 publications

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

A directly comparative two-gate case–control diagnostic accuracy study of the pure tone screen and HearCheck screener tests for identifying hearing impairment in school children

Axonal Projection Patterns of the Dorsal Interneuron Populations in the Embryonic Hindbrain

Contact Info

Product

Resources

About