Heart and brain interactions in heart failure: Cognition, depression, anxiety, and related outcomes

Rigueira, J; Agostinho, João R.; Aguiar-Ricardo, I; Gonçalves, Inês; Santos, R; Nunes-Ferreira, A; Rodrigues, Tiago; Cunha, Nelson; André, ŃZinga; Pires, Raquel; Veiga, Francisco José; Pedro, Maria Isabel; Pinto, Fausto J.; Brito, Dulce

doi:10.1016/j.repc.2020.09.009

Cited by 4 publications

(11 citation statements)

References 48 publications

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“…This is in line with studies in Indonesia which found that impaired cognitive function in HF ranged from 50.7%-95% (Arifin & Fitri, 2021;Birowo et al, 2010;Saputra et al, 2020). This number is greater than the global rate which ranges from 25%-75% (Lee et al, 2019;Rigueira et al, 2021).…”

Section: Discussionsupporting

confidence: 84%

“…Heart failure is not limited to the heart itself, but involves the entire body system, including the central nervous system. Brain-cardiac involvement is believed to be a bidirectional and multifaceted interaction (Ovsenik, Podbregar, & Fabjan, 2021;Rigueira, Agostinho, Aguiar-Ricardo, Gonçalves, Santos, Nunes-Ferreira, Rodrigues, Cunha, André, Pires, Veiga, Mendes Pedro, Pinto, & Brito, 2021).…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Impaired heart function can affect the brain causing cognitive impairment, anxiety, and depression, which in turn can contribute to further worsening of HF (Rigueira et al, 2021). Impaired cognitive function in HF has a very high prevalence of 25%-75% (Lee, Qian, Liu, Graham, Mann, Nakanishi, Teerlink, Lip, Freudenberger, Sacco, Mohr, Labovitz, Ponikowski, Lok, Matsumoto, Estol, Anker, Pullicino, Buchsbaum, & Di Tullio, 2019;Rigueira et al, 2021). Studies in Indonesia found that the prevalence of cognitive function impairment in HF tends to be higher than globally, namely 50.7%-95% (Arifin & Fitri, 2021;Birowo, Lastri, Makmun, & Prihartono, 2010;Saputra, Adnyana, Laksmidewi, Gelgel, & Widyadharma, 2020).…”

Section: Introductionmentioning

confidence: 99%

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Cognitive function and related factors in patients with heart failure

Arseda,

Pahria,

Kurniawan

2024

Internat.Jrnl.

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Background: Impaired cognitive function is associated with poor outcomes, frequent hospitalization, and high mortality in HF. Purpose: To determine the prevalence of cognitive function in HF and what factors contribute. Method: This study was an observational analysis with cross-sectional. Study subjects: HF patients at the Cardiac Polyclinic of Dr. M. Haulussy Hospital, Ambon, Indonesia from August to September 2023, with Inclusion criteria: aged 40-65 years; able to communicate well; not having a stroke or other neurological disorders (Parkinson's disease, Alzeimer's disease, Multiple Sclerosis) or other cognitive function disorders (such as due to injury or substance abuse); can read and write. Exclusion criteria: worsening of physical condition such as loss of consciousness and worsening of symptoms such as severe shortness of breath, inability to communicate, inability to complete the questionnaire, and worsening of symptoms that do not improve after being rested when data collection is carried out. Results: HF patients were male (56.2%), had ≥ 12 years of education (72.4%), were not actively working (56.9%), suffered from HF with NYHA class II functional status (49.1%), had Coronary Artery Disease (CAD) comorbid only (49.2%), had experienced hospitalization (64.6%), and were obese (51.54%). Respondents had an average age of 57.08 ± 6.78 years, a duration of HF of 3.96 ± 4.35 years, an average body mass index of 25.65 ± 4.5 Kg/m2, normal blood pressure with an average systole of 122.73 ± 17.21 mmHg, and an average diastole of 77.44 ± 10.11 mmHg. HF patients who experienced impaired cognitive function were 87.69% with mild cognitive impairment 73.1%, moderate cognitive impairment 13.1%, and severe cognitive impairment 1.5%. The maximum score of MoCA sub-domains of executive function was 46.2%; visuospatial 35.4%; attention 37.7%, naming and language 20%; abstraction 33.8%, delayed memory 3.8% and orientation 86.9%. There was a significant correlation between cognitive function and age (ρ = 0.000; r = -0.324), education level (ρ = 0.000; r = 0.327), and New York Heart Association functional status (ρ = 0.021; r = -202). Conclusion: There is a high prevalence of impaired cognitive function in chronic HF patients accompanied by a global decline in cognitive function subdomains. Factors that may contribute to HF cognitive function include age, education level, not actively working, New York Heart Association functional status, comorbidities, and obesity.

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Section: Discussionsupporting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Cognitive function and related factors in patients with heart failure

Arseda,

Pahria,

Kurniawan

2024

Internat.Jrnl.

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“…Cognitive function impairment among patients with heart failure (HF) is one of the most common and serious health problems. Previous studies noted that 25% to 95% of patients with HF have cognitive function impairment (Arifin, 2021 ; Lee et al, 2019 ; Rigueira et al, 2021 ). Cognitive function includes all processes used by individuals to organize information through sensory input from the environment, transduction (perception/visuospatial), concentration (attention), information storage (memory), verbalization, and finally, implementation of information (psychomotor) (Bostrom & Sandberg, 2009 ).…”

Section: Introductionmentioning

confidence: 97%

Mapping cognitive function screening instruments for patients with heart failure: A scoping review

Arseda,

Pahria,

Kurniawan

2024

Belitung Nurs J

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Background: Patients with heart failure (HF) often experience cognitive impairment, which negatively affects their quality of life. An effective screening tool is essential for nurses and healthcare professionals to assess cognitive function as part of HF management. Although many instruments exist, none are specifically designed for patients with HF. Objective: This study aimed to map the instruments for screening cognitive function in patients with HF. Design: A scoping review. Data Sources: Articles published between 2019 and 2023 were searched in PubMed, ScienceDirect, and Google Scholar, with the last search conducted on 27 January 2024. Review Methods: The review followed the scoping review framework by Arksey and O’Malley and adhered to PRISMA guidelines for scoping reviews. Results: Of the 21 articles meeting inclusion criteria, six cognitive function screening instruments were used across various cognitive domains, effectively identifying cognitive impairment in both inpatient and outpatient HF settings. The Montreal Cognitive Assessment (MoCA) was the most frequently used tool, covering a broad range of cognitive domains. MoCA showed high efficacy with a kappa coefficient of 0.82, Cronbach’s alpha reliability of 0.75, sensitivity of 90%, and specificity of 87%. Conclusion: Instruments like MoCA, Mini-Cog, and TICS-m show promise for assessing cognitive function in patients with HF, each with specific strengths and limitations. MoCA is notable for its comprehensive coverage despite being time-consuming and having language barriers. Further research is needed to revalidate and improve the existing instruments. It is crucial for nurses and healthcare professionals to integrate these tools into regular patient management, highlighting the need for continued research in their application.

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Mental involvement in heart failure

Doehner

2021

Revista Portuguesa de Cardiologia

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Heart and brain interactions in heart failure: Cognition, depression, anxiety, and related outcomes

Cited by 4 publications

References 48 publications

Cognitive function and related factors in patients with heart failure

Cognitive function and related factors in patients with heart failure

Mapping cognitive function screening instruments for patients with heart failure: A scoping review

Mental involvement in heart failure

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