Heart Failure in Africa, Asia, the Middle East and South America: The INTER-CHF study

Dokainish, Hisham; Teo, Koon; Zhu, Jun; Roy, Ambuj; AlHabib, Khalid F.; ElSayed, Ahmed; Palileo-Villaneuva, Lia; López‐Jaramillo, Patricio; Karaye, K.M.; Yusoff, Khalid; Orlandini, Andrés; Sliwa, Karen; Mondo, Charles; Lanas, Fernando; Prabhakaran, Dorairaj; Badr, Amr; ElMaghawry, Mohamed; Damasceno, Albertino; Tibazarwa, Kemi; Belley‐Côté, Emilie P.; Balasubramanian, Kumar; Yacoub, Magdi H.; Huffman, Mark D.; Harkness, Karen; Grinvalds, Alex; McKelvie, Robert S.; Yusuf, Salim

doi:10.1016/j.ijcard.2015.11.183

Cited by 132 publications

(150 citation statements)

References 26 publications

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“…The leading causes of HF in Africa are hypertensive heart disease and dilated cardiomyopathy. [41][42][43] In Asia the proportion of patients in NYHA class III/IV is similar to that in NYHA class II. 17,41,44 Coronary artery disease is the leading HF aetiology.…”

Section: Demographic and Clinical Characteristicsmentioning

confidence: 97%

“…One study showed that in Africa HF patients are younger than in other regions, with most being NYHA class III/IV and having valve disease. 41 Half of these HF patients are male and 29 % have HFpEF. The leading causes of HF in Africa are hypertensive heart disease and dilated cardiomyopathy.…”

Section: Demographic and Clinical Characteristicsmentioning

confidence: 99%

“…41,45 In South America the most common cause of HF is coronary artery 49 The Management Predischarge Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) study reported that >50 % of patients were discharged with unresolved symptoms, and within 60 days half had worsening symptoms, a quarter were re-hospitalised and >10 % died. 50 The Canadian Enhanced Feedback for Effective Cardiac Treatment (EFFECT) study enrolling 1,570 patients with HFrEF and 880 with HFpEF reported no differences in mortality at 30 days (7.1 % and 5.3 %, respectively) and 1 year (25.5 % and 22.2 %, respectively).…”

Section: Demographic and Clinical Characteristicsmentioning

confidence: 99%

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Global Public Health Burden of Heart Failure

Savarese

Lund

2017

Cardiac Failure Review

2,139

1,366

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EpidemiologyAccess at: www.CFRjournal.com Heart failure (HF) is a complex clinical syndrome characterised by the reduced ability of the heart to pump and/or fill with blood. In this review we describe the epidemiology of HF, providing data about the prevalence, incidence, mortality and morbidity worldwide. Prevalence and IncidenceCurrently 5.7 million people in the US have HF, but the projections are worrisome since it is expected that by 2030 more than 8 million people will have this condition, accounting for a 46 % increase in prevalence (see Figure 1). In Japan around 1 million people have the condition, accounting for 1 % of the population. [14][15][16] In India the estimates range between 1.3 and 4.6 million, which translates to a prevalence of 0.12-0.44 %, although this may be underestimated. 17 In Southeast Asia 9 million people have HF; with a prevalence of 6.7 % in Malaysia and 4.5 % in Singapore. 4,18 In South America the HF prevalence is 1 % and in Australia it ranges between 1 % and 2 %, similar to Western countries (see Figure 2). 19,20Although aetiologies and clinical characteristics have been studied in Sub-Saharan Africa, 21 there are actually no population studies providing insight into prevalence or incidence . AbstractHeart failure (HF) is a global pandemic affecting at least 26 million people worldwide and is increasing in prevalence. HF health expenditures are considerable and will increase dramatically with an ageing population. Despite the significant advances in therapies and prevention, mortality and morbidity are still high and quality of life poor. The prevalence, incidence, mortality and morbidity rates reported show geographic variations, depending on the different aetiologies and clinical characteristics observed among patients with HF. In this review we focus on the global epidemiology of HF, providing data about prevalence, incidence, mortality and morbidity worldwide.

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Section: Demographic and Clinical Characteristicsmentioning

confidence: 97%

Section: Demographic and Clinical Characteristicsmentioning

confidence: 99%

Section: Demographic and Clinical Characteristicsmentioning

confidence: 99%

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Global Public Health Burden of Heart Failure

Savarese

Lund

2017

Cardiac Failure Review

2,139

1,366

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“…However, it should be noted that the etiology, prevalence, management, and outcomes of HF vary among the countries within the Region [9, 22]. For instance, a large prospective cohort study of HF across Africa, Asia, the Middle East, and South America (International Congestive Heart Failure [INTER-CHF]) found that the primary etiology of HF in the Middle East and Asia was ischemic heart disease, as in Western countries [10, 23], while in Africa, the leading cause of HF was hypertension [23]. This finding is consistent with the sub-Saharan Africa Survey of Heart Failure (THESUS-HF), which found that nonischemic causes (most commonly hypertension) were the predominant etiology underlying HF in sub-Saharan Africa overall, with some variation across African countries [13].…”

Section: Introductionmentioning

confidence: 99%

Supporting the Management of Patients with Heart Failure within Asia-Pacific, Middle East, and African Countries: A Toolbox for Healthcare Providers

et al. 2019

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Objectives: The management of heart failure (HF) is most effective when established treatment guidelines and recommendations are followed. We aimed to develop a “Toolbox” of resources to facilitate the care of patients with acute HF and chronic HF with reduced ejection fraction delivered by healthcare professionals across Asia-Pacific, the Middle East and Africa (henceforth referred to as the “Region”). Methods: We convened a group of cardiologists from across the Region to develop a set of checklists, algorithms, and other practical resources. These resources are based on our experiences, current evidence, and international guidelines. Results: The HF Toolbox comprises three simplified sets of resources for use in the Emergency Room (ER), hospital and outpatient settings. Resources include admission and discharge checklists, treatment algorithms, recommendations for forming a multidisciplinary team, patient education, and self-management materials, and key performance indicators to monitor whether standards of care are met or maintained, or should be improved. Conclusions: The HF Toolbox provides practical resources to simplify the management of patients with HF and to support the formation of HF programs in the Region. The Toolbox is aligned with current guideline recommendations and can support the management of patients from presentation in the ER, through hospital admission to outpatient care.

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“…Ensuring equity of care for all patients by delivering timely access to diagnostic services and treatment of heart failure is one of the key aspects highlighted by this initiative. Several recent reports clearly demonstrate, however, that there is still significant regional variability in several facets of the diagnosis and management of heart failure across different parts of the world 2. Moreover, healthcare system organisation and resource use also vary greatly, producing major constrains to patients’ care, particularly in low-income to middle-income countries.…”

mentioning

confidence: 99%