2018
DOI: 10.1016/j.cardfail.2017.09.005
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Heart Failure With Recovered Ejection Fraction in African Americans: Results From the African-American Heart Failure Trial

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Cited by 18 publications
(19 citation statements)
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“…In our study population, HFbEF patients were more likely to have a non-ischemic cardiomyopathy, HF of shorter duration, higher baseline LVEF, and to be treated with bucindolol compared to those who did not recover their LVEF. These findings are highly consistent with the results of other work (5,16,17). Such a strong signature of recovery potential suggests an innate biology that underlies functional recovery.…”
Section: Discussionsupporting
confidence: 91%
See 1 more Smart Citation
“…In our study population, HFbEF patients were more likely to have a non-ischemic cardiomyopathy, HF of shorter duration, higher baseline LVEF, and to be treated with bucindolol compared to those who did not recover their LVEF. These findings are highly consistent with the results of other work (5,16,17). Such a strong signature of recovery potential suggests an innate biology that underlies functional recovery.…”
Section: Discussionsupporting
confidence: 91%
“…Since these therapies are well-known to affect reverse remodeling and recovery of LVEF, our findings might underestimate recovery potential in current practice. Of note, similar analyses in a more contemporary trial and real-world cohort appear to observe a similar if not higher proportion of LVEF improvement despite similar predictors of LVEF recovery (6,17,21). A second potential issue is the definition of recovery.…”
Section: Discussionmentioning
confidence: 82%
“…In addition to the effect on mortality and hospitalization outcomes, Peter Wohlfahrt et al confirmed that HFrecEF significantly improved the quality of life in patients with heart failure ( 9 ). However, the prognostic effect of recovered ejection fraction was inconsistent or even non-significant ( 10 , 12 , 16 ). After a systematic review of all relevant reports, we have pooled the quantified impact of HFrecEF on prognosis, which provided explicit evidence that HFrecEF, recently redefined as HFimpEF, is a novel entity in patients with heart failure needing more attention and evaluation.…”
Section: Discussionmentioning
confidence: 99%
“…To evaluate the association between BMI and EF recovery, we performed analyses that categorized the HFrEF into two classes depending on data from their follow-up echocardiograms. Patients with EF ≥40% were considered to have HFrecEF, according to the suggestion that these patients may be clinically distinct from those with persistently reduced EF ( 17 , 18 ). The other participants were considered to have persistent HFrEF.…”
Section: Methodsmentioning
confidence: 99%