Heart palpitation relief with Melissa officinalis leaf extract: Double blind, randomized, placebo controlled trial of efficacy and safety

Alijaniha, Fatemeh; Naseri, Mohsen; Afsharypuor, Suleiman; Fallahi, Faramarz; Noorbala, Ahmad-Ali; Mosaddegh, Mahmoud; Faghihzadeh, Soghrat; Sadrai, Sima

doi:10.1016/j.jep.2015.02.007

Cited by 65 publications

(48 citation statements)

References 31 publications

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“…Bitter orange blossom (Citus aurantium; Akhlaghi et al, 2011), curcumin (Curcuma longa; Yu, Pei, Zhang, Wen, & Yang, 2015), Melissa officinalis (Alijaniha et al, 2015), and Siberian Ginseng (Eleutherococcus senticosis; Schaffler, Wolf, & Burkart, 2013) were also found to have some benefit in lowering anxiety and depression in clinical studies, but these symptoms were not the primary endpoints.…”

Section: Resultsmentioning

confidence: 99%

Herbal medicine for depression and anxiety:Asystematic review with assessment of potential psycho‐oncologic relevance

Yeung

Hernandez

Mao

et al. 2018

Phytotherapy Research

176

100

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Anxiety and depression are prevalent among cancer patients, with significant negative impact. Many patients prefer herbs for symptom relief to conventional medications which have limited efficacy/side effects. We identified single-herb medicines that may warrant further study in cancer patients. Our search included PubMed, Allied and Complementary Medicine, Embase, and Cochrane databases, selecting only single-herb randomized controlled trials between 1996 and 2016 in any population for data extraction, excluding herbs with known potential for interactions with cancer treatments. One hundred articles involving 38 botanicals met our criteria. Among herbs most studied (≥6 randomized controlled trials each), lavender, passionflower, and saffron produced benefits comparable to standard anxiolytics and antidepressants. Black cohosh, chamomile, and chasteberry are also promising. Anxiety or depressive symptoms were measured in all studies, but not always as primary endpoints. Overall, 45% of studies reported positive findings with fewer adverse effects compared with conventional medications. Based on available data, black cohosh, chamomile, chasteberry, lavender, passionflower, and saffron appear useful in mitigating anxiety or depression with favorable risk-benefit profiles compared to standard treatments. These may benefit cancer patients by minimizing medication load and accompanying side effects. However, well-designed larger clinical trials are needed before these herbs can be recommended and to further assess their psycho-oncologic relevance.

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Section: Resultsmentioning

confidence: 99%

Herbal medicine for depression and anxiety:Asystematic review with assessment of potential psycho‐oncologic relevance

Yeung

Hernandez

Mao

et al. 2018

Phytotherapy Research

176

100

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“…Результати останніх досліджень вказують на антитривожну активність Melissa officinalis при гострому психоемоційному стресі [32], меліса також покращує когнітивні функції [33]. За результатами подвійного сліпого рандомізованого плацебо-контрольованого дослідження, у пацієнтів, які вживали Melissa officinalis, зменшилась частота епізодів серцебиття й тривожність [34].…”

Section: рисунок 1 магній як антагоніст глутаматного рецептора [15 unclassified

Фармакологічна Корекція Стрес-Індукованих Вегетативних Порушень Та Інсомнії У Дітей

Кhaitovych¹

2021

INJ

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Фармакологічна корекція стрес-індукованих вегетативних порушень та інсомнії у дітей Резюме. У статті наведено механізми розвитку стрес-індукованої вегетативної дисфункції й інсомнії. Обговорюється можливість застосування при даних станах комплексного препарату Сілента. Детально розглядаються фармакодинаміка його компонентів і дані доказової медицини щодо їх застосування. Описано механізми стрес-лімітуючої дії магнію (антагонізм щодо глутаматного рецептора) та L-триптофану (джерело утворення нікотинамідних коферментів, серотоніну й мелатоніну). Комбінація екстрактів квіток ромашки аптечної, листя меліси лікарської, суцвіть липи широколистої гармонізує баланс збудливих і гальмівних процесів у центральній нервовій системі; зменшує психоемоційне напруження, дратівливість, тривожність, страхи, психовегетативні прояви та інсомнію.

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“…The species M. officinalis ("erva-cidreira") is mainly prescribed for the treatment of the anxiety and flatulence. Alijaniha, et al 34 described the safety and effectiveness of M. officinalis in patients suffering from benign palpitations, and as a promising anxiolytic drug without any considerable side effects. Amsterdam, et al 35 reported a modest anxiolytic activity of M. chamomilla extract in patients with mild to moderate Generalized Anxiety Disorder.…”

Section: Professional Work In the Field Of Medicinal Plants And Phytomentioning

confidence: 99%

Medicinal Plants in Basic Care: A Study of Clinical Practice

Souza¹,

Andrade²,

Ramos³

et al. 2019

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Ethical approval for the study Ethical approval for this ethnopharmacological survey was obtained from the Ethics and Research Committee of the University Hospital of Sergipe (CAE: 61094816.6.0000.5546). The participants were adequately informed about the nature of study, and benefits and risks involved. The subjects who agreed to participate of the study signed a written consent document. Characterization of Brazilian health care Ever since 1988, the Brazilian Constitution has promised free public healthcare in all complexity levels through the SUS, founded by taxes and social contributions. The SUS, by means of FHS, has decentralized care coverage and proved to reduce common diseases, mortality rate, and unnecessary admissions. 7 Alive pharmacy The alive pharmacy presents in the health units constitute medicinal gardens where are carried out activities such as cultivation, processing and management of medicinal plants, ensuring their correct and safe use in basic care.

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Heart palpitation relief with Melissa officinalis leaf extract: Double blind, randomized, placebo controlled trial of efficacy and safety

Cited by 65 publications

References 31 publications

Herbal medicine for depression and anxiety:Asystematic review with assessment of potential psycho‐oncologic relevance

Herbal medicine for depression and anxiety:Asystematic review with assessment of potential psycho‐oncologic relevance

Фармакологічна Корекція Стрес-Індукованих Вегетативних Порушень Та Інсомнії У Дітей

Medicinal Plants in Basic Care: A Study of Clinical Practice

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