Heart Rate Response During Exercise Predicts Survival in Adults With Congenital Heart Disease

Abstract

An abnormal heart rate response to exercise identifies ACHD patients with a higher risk of mortality in the midterm, even after accounting for antiarrhythmic medication and exercise capacity. Heart rate reserve is a simple and inexpensive way to identify ACHD patients at higher mortality risk.

Clinical Outcomes of Surgical Pulmonary Valve Replacement After Repair of Tetralogy of Fallot and Potential Prognostic Value of Preoperative Cardiopulmonary Exercise Testing

“…It is reasonable to presume that patients referred for PVR in the earlier era were at a later stage of disease progression. Their reduced peak oxygen uptake 32,33 or blunted heart rate reserve 34 and increased V .…”

Heart Rate Response During Exercise and Pregnancy Outcome in Women With Congenital Heart Disease

“…6 -10 Chronotropic variables remained an independent risk of mortality independent of the use of antiarrhythmic medication. 6,8,23 Furthermore, Diller et al demonstrated that chronotropic incompetence is prevalent in 62% of adults with CHD, and measures of heart rate response are as good as pV O2 in predicting mortality in this population. 6 Our current study expands on these findings by identifying a low CRI as a potential risk factor for pregnancy outcome in women with CHD.…”

Exercise Testing and Training in Children With Congenital Heart Disease

“…These new indices have not been studied widely in pediatric patients, and their relevance to this population remains uncertain. 28,29 Chronotropic incompetence (ie, an inability to increase HR to Ͼ80% of predicted at peak exercise) is common after surgery for CHD 6,28,30,31 and has been associated with a poor prognosis. 30 …”