2005
DOI: 10.1016/j.jacc.2004.10.033
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Heart rate turbulence after atrial premature beats before spontaneous onset of atrial fibrillation

Abstract: Altered heart rate dynamics, suggesting transient enhancement of vagal outflow after premature atrial excitation, are temporally related to spontaneous onset of clinical AF.

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Cited by 37 publications
(29 citation statements)
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“…Multiple studies in patients with paroxysmal AF have shown increased APC activity right before the onset of AF imputing them as likely triggers. [7][8][9] Pulmonary vein isolation and ablation performed for treatment of AF has been shown to significantly reduce APC frequency. 14,15 In contrast, incomplete APC suppression in these patients was associated with higher AF recurrence.…”
Section: Accepted Manuscriptmentioning
confidence: 99%
See 1 more Smart Citation
“…Multiple studies in patients with paroxysmal AF have shown increased APC activity right before the onset of AF imputing them as likely triggers. [7][8][9] Pulmonary vein isolation and ablation performed for treatment of AF has been shown to significantly reduce APC frequency. 14,15 In contrast, incomplete APC suppression in these patients was associated with higher AF recurrence.…”
Section: Accepted Manuscriptmentioning
confidence: 99%
“…6 Though shown to trigger paroxysmal AF, they are, at present, considered innocuous and generally left untreated. [7][8][9] Our hypothesis is that patients with frequent and recurrent APCs are more likely to develop AF. …”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, the values of ApEn before the onset of AF were lower compared with the values obtained from matched healthy control subjects. In a more recent study [Vikman et al, 2005] these results could be confirmed, however a more predictive parameter for AF was found: the turbulence onset (TO). TO was significantly less negative during the 1 h preceding AF than during the non-AF hours (0.71 ± 1.76 versus −0.35±1.46, p < 0.00001).…”
Section: Further Applicationsmentioning
confidence: 78%
“…Also, increasing age is associated with a decrease in the HRT index [60]. It is reported in [67] that TO is significantly less According to the discussion above, we use PLFME for the cardiac signal. Specifically, in PLFME, the original time series is filtered by the piecewise linear filter A defined in (2.1) recursively at multiple scales.…”
Section: Application To Human Heartbeat Interval Time Seriesmentioning
confidence: 97%