Heart Rate Variability and Cardiovascular Fitness: What We Know so Far

Souza, Hugo Celso Dutra de; Philbois, Stella Vieira; Veiga, Ana Catarine; Aguilar, Bruno Augusto

doi:10.2147/vhrm.s279322

Cited by 41 publications

(35 citation statements)

References 150 publications

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“…This all points toward dysfunction of the autonomic system in patients with type II diabetes. Along this line of thought, several studies report disturbed function of the autonomic nervous system as a risk factor for cardiovascular disease ( 57 , 58 ), which also has a higher prevalence in diabetic patients ( 59 , 60 ). Interestingly, there also seems to be a link between the autonomic nervous system and the vascular endothelium in that sense that both act in opposition in order to regulate vascular tone ( 61 ).…”

Section: Discussionmentioning

confidence: 98%

Neuro-vascular coupling and heart rate variability in patients with type II diabetes at different stages of diabetic retinopathy

et al. 2022

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Aims/HypothesisThere is evidence that diabetes is accompanied by a break-down of functional hyperemia, an intrinsic mechanism of neural tissues to adapt blood flow to changing metabolic demands. However, to what extent functional hyperemia is altered in different stages of diabetic retinopathy (DR) in patients with type II diabetes is largely unknown. The current study set out to investigate flicker-induced retinal blood flow changes in patients with type II diabetes at different stages of DR.Materials and methodsA total of 76 subjects were included in the present parallel-group study, of which 56 had diabetes with either no DR or different stages of non-proliferative DR (n = 29 no DR, 12 mild DR, 15 moderate to severe DR). In addition, 20 healthy subjects were included as controls. Retinal blood flow was assessed before and during visual stimulation using a combined measurement of retinal vessel calibers and blood velocity by the means of Doppler optical coherence tomography (OCT). To measure systemic autonomic nervous system function, heart rate variability (HRV) was assessed using a short-term orthostatic challenge test.ResultsIn healthy controls, retinal blood flow increased by 40.4 ± 27.2% during flicker stimulation. Flicker responses in patients with DR were significantly decreased depending on the stage of the disease (no DR 37.7 ± 26.0%, mild DR 26.2 ± 28.2%, moderate to severe DR 22.3 ± 13.9%; p = 0.035, ANOVA). When assessing systemic autonomous neural function using HRV, normalized low frequency (LF) spectral power showed a significantly different response to the orthostatic maneuver in diabetic patients compared to healthy controls (p < 0.001).Conclusion/InterpretationOur study indicates that flicker induced hyperemia is reduced in patients with DR compared to healthy subjects. Further, this impairment is more pronounced with increasing severity of DR. Further studies are needed to elucidate mechanisms behind the reduced hyperemic response in patients with type II diabetes.Clinical trial registration[https://clinicaltrials.gov/], identifier [NCT03 552562].

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Section: Discussionmentioning

confidence: 98%

Neuro-vascular coupling and heart rate variability in patients with type II diabetes at different stages of diabetic retinopathy

et al. 2022

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“…Similarly, exercise and physical activity are positively correlated with better health outcomes, including mood and reproductive functions, as well as alleviation of physical symptoms and pain [60][61][62][63][64]. Finally, lower heart rate and higher heart-rate variability (HRV) have been associated with better health and mental health [65,66], whereas the inverse pattern is associated with ill-health conditions, such as polycystic ovary syndrome and uterine fibroids [67][68][69].…”

Section: Introductionmentioning

confidence: 99%

“…40,42,43 Finally, the Flo app connects to a variety of wearable devices which collect sleep, heart rate and physical activity data. Lower heart rate and higher heart-rate variability (HRV) have been associated with better health and mental health, 53,54 whereas the inverse pattern is associated with illhealth conditions, such as polycystic ovary syndrome and uterine fibroids. [55][56][57] The aim of the current study was to measure the impact of disturbances related to the menstrual cycle on workrelated productivity in users of the Flo app.…”

Section: Introductionmentioning

confidence: 99%

Menstrual cycle-associated symptoms and workplace productivity in US employees: A cross-sectional survey of users of the Flo mobile phone app

Ponzo

Wickham²,

Bamford³

et al. 2022

DIGITAL HEALTH

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Objective Mood and physical symptoms related to the menstrual cycle affect women's productivity at work, often leading to absenteeism. However, employer-led initiatives to tackle these issues are lacking. Digital health interventions focused on women's health (such as the Flo app) could help fill this gap. Methods 1867 users of the Flo app participated in a survey exploring the impact of their menstrual cycle on their workplace productivity and the role of Flo in mitigating some of the identified issues. Results The majority reported a moderate to severe impact of their cycle on workplace productivity, with 45.2% reporting absenteeism (5.8 days on average in the previous 12 months). 48.4% reported not receiving any support from their manager and 94.6% said they were not provided with any specific benefit for issues related to their menstrual cycle, with 75.6% declaring wanting them. Users stated that the Flo app helped them with the management of menstrual cycle symptoms (68.7%), preparedness and bodily awareness (88.7%), openness with others (52.5%), and feeling supported (77.6%). Users who reported the most positive impact of the Flo app were 18–25% less likely to report an impact of their menstrual cycle on their productivity and 12–18% less likely to take days off work for issues related to their cycle. Conclusions Apps such as Flo could equip individuals with tools to better cope with issues related to their menstrual cycle and facilitate discussions around menstrual health in the workplace.

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“…The effects of mining activities on cardiopulmonary functions have been investigated in previous studies, as reviewed in [ 16 ]. Cardiovascular fitness can be monitored by measuring the heart rate variability [ 17 ]. Meanwhile, cardiopulmonary performance can also be monitored by measuring oxygen uptake (VO 2 max) [ 18 ], which is widely used in sport science [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

Pulmonary Capacity, Blood Composition and Metabolism among Coal Mine Workers in High- and Low-Altitude Aboveground and Underground Workplaces

Wang

Chen

et al. 2022

IJERPH

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(1) Background: While previous studies revealed how underground mining might adversely affect the cardiopulmonary functions of workers, this study further investigated the differences between under- and aboveground mining at both high and low altitudes, which has received little attention in the literature. (2) Methods: Seventy-one healthy male coal mine workers were recruited, who had worked at least 5 years at the mining sites located above the ground at high (>3900 m; n = 19) and low (<120 m; n = 16) altitudes as well as under the ground at high (n = 20) and low (n = 16) altitudes. Participants’ heart rates, pulmonary functions, total energy expenditure and metabolism were measured over a 5-consecutive-day session at health clinics. (3) Results: Combining the results for both above- and underground locations, workers at high-altitude mining sites had significantly higher peak heart rate (HR), minimum average HR and training impulse as well as energy expenditure due to all substances and due to fat than those at low-altitude sites. They also had significantly higher uric acid, total cholesterol, creatine kinase and N-osteocalcin in their blood samples than the workers at low-altitude mining sites. At underground worksites, the participants working at high-altitude had a significantly higher average respiratory rate than those at low-altitude regions. (4) Conclusion: In addition to underground mining, attention should be paid to high-altitude mining as working under a hypoxia condition at such altitude likely presents physiological challenges.

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Heart Rate Variability and Cardiovascular Fitness: What We Know so Far

Cited by 41 publications

References 150 publications

Neuro-vascular coupling and heart rate variability in patients with type II diabetes at different stages of diabetic retinopathy

Neuro-vascular coupling and heart rate variability in patients with type II diabetes at different stages of diabetic retinopathy

Menstrual cycle-associated symptoms and workplace productivity in US employees: A cross-sectional survey of users of the Flo mobile phone app

Pulmonary Capacity, Blood Composition and Metabolism among Coal Mine Workers in High- and Low-Altitude Aboveground and Underground Workplaces

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