Heart rate variability improvement in children using transcatheter atrial septal defect closure

Özyılmaz, İsa; Ergül, Yakup; Tola, Hasan Tahsin; Saygı, Murat; Öztürk, Erkut; Öztürk, Erkut; Tosun, Öykü; Özyılmaz, Sinem; Gül, Mehmet; Güzeltaş, Alper; Ödemiş, Ender; Bakır, İhsan

doi:10.5152/akd.2015.5922

Cited by 8 publications

(10 citation statements)

References 26 publications

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“…Third, another issue to be considered is the effect of nonlinear and non-stationary processes that have necessarily to be present in these critically ill patients [22,23,33], and that can be overcome using appropriate methods for the analysis of HRV indices, as those used in this study. Fourth and finally, the inclusion for the spectral analysis of HRV indices of the very high frequency range (0.4 -0.6 Hz), that has been not extensively studied, but that has shown evidences of pathophysiologic interest in the last years [70,71,[99][100][101]. All these issues were considered in our study and possibly are associated to better results, so we recommend them for later use in this field.…”

Section: Discussionmentioning

confidence: 96%

“…Later, other authors [125,126] demonstrated that the VHF peaks were not artifactual, and that its presence could serve as a diagnostic test for vagal denervation, and even classified the VHF peaks into two types associated to possible different pathophysiologic significance [127]. Other authors have reported differences of VHF spectral measures between patients with cardiologic disturbances and healthy controls [99,100]. Recently [101] we have shown, using three spectral methods, including the Hilbert- Considering the whole group of patients, the observed proportion was of 10 in 47 patients (21.2 %).…”

Section: Very High Frequency Oscillations Of Patients In Comamentioning

confidence: 99%

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Autonomic impairment of patients in coma with different Glasgow coma score assessed with heart rate variability

et al. 2019

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Primary objective: To assess and compare the functional state of the autonomic nervous system in healthy individuals with patients in coma using measures of heart rate variability (HRV), and to evaluate its efficiency in predicting mortality. Research design: Retrospective group comparison study of patients in coma, classified into two subgroups, according to their Glasgow coma score, with a healthy control group. Methods and procedures: HRV indices were calculated from 7 minutes of free of artifacts electrocardiograms using the Hilbert-Huang method in the spectral range 0.02-0.6 Hz. A special procedure was applied to avoid the effect of confounding factors. Stepwise multiple regression logistic analysis (SMLRA), followed by ROC curve analysis were applied to evaluate predictions. Results: Progressive reduction of HRV associated with deepening of coma was confirmed and a mortality score model including three spectral HRV indices: absolute power values of the very low, low frequency, and the power in normalized units of the very high frequency bands (0.4-0.6 Hz). The SMLRA model showed sensitivity of 95.65%, specificity of 95.83%, positive predictive value of 95.65%, and overall efficiency of 95.74%. Conclusions: HRV is a reliable method to assess the integrity of the neural control of the caudal brainstem centres upon the heart, of patients in coma, and predict mortality.

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Section: Discussionmentioning

confidence: 96%

Section: Very High Frequency Oscillations Of Patients In Comamentioning

confidence: 99%

Autonomic impairment of patients in coma with different Glasgow coma score assessed with heart rate variability

et al. 2019

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“…It has been shown that HRV is reduced in children with ASD [ 4 , 5 ]. Surgery or transcatheter closure can improve HRV in pediatric patients [ 6 – 8 ]. However, there is not much research on HRV in adult patients with ASD.…”

Section: Introductionmentioning

confidence: 99%

Early changes in ambulatory electrocardiography after transcatheter closure in patients with atrial septal defect and factors affecting heart rate variability

Cao

Zhang

et al. 2020

BMC Cardiovasc Disord

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Background Factors affecting heart rate variability (HRV) in patients with atrial septal defect (ASD) have not been clarified. This study sought to identify those factors and establish a preliminary risk model. Methods A total of 154 patients with ASD who underwent transcatheter closure and met the study requirements were analyzed in this study. Moreover, 26 patients with patent foramen ovale (PFO) were enrolled in our study as a control group. All patients underwent echocardiography and ambulatory electrocardiography before and one day after the procedure. Results The standard deviation of all normal-to-normal (NN) intervals (SDNN) and the standard deviation of the averages of the NN intervals in all 5 min segments of the entire recording (SDANN) were significantly higher and the heart rate was lower after closure than before closure in patients with ASD (SDNN: 6.08, 95% CI 3.00 to 9.15, p < 0.001; SDANN: 7.57, 95% CI 4.50 to 10.64, p < 0.001; heart rate: -1.17, 95% CI − 2.86 to − 0.48, p = 0.006). Multiple regression analyses indicated that age, sex, defect diameter, heart rate and diabetes were significantly associated with HRV indices (SDNN: R2 = 0.415; P < 0.001). SDNN and SDANN had obvious correlations with right ventricular systolic pressure (SDNN: R = − 0.370, p < 0.001; SDANN: R = − 0.360, p < 0.001). Conclusions Factors affecting HRV in patients with ASD include age, sex, heart rate, defect size and diabetes. Furthermore, right ventricular systolic pressure plays an important role in the change in HRV.

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“…Özyılmaz et al 28 in their study observed children with ASD before and after the endovascular treatment. The criteria for inclusion in the study were: ASD of more than according to ECHO data and the possibility of catheter closure of the defect.…”

Section: Features Of Hrv Dynamics After Surgical and Endovascular Cormentioning

confidence: 99%

Heart rate variability in atrial septal defect both before and after operation

2019

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SOUHRNV posledních desetiletích se značný zájem soustřeďuje na studium vlivu autonomního (vegetativního) nervového systému na srdce a jeho hodnocení jako prediktoru mortality v důsledku postižení srdce a rozvoje kardiovaskulárních komplikací. Analýza variability srdeční frekvence (heart rate variability, HRV) představuje jednoduchou, neinvazivní a bezpečnou metodu studia regulace kardiovaskulárního systému člověka autonomním nervovým systémem. Podle některých autorů může -u pacientů se strukturálními defekty septa -zmenšení HRV v důsledku objemového přetížení srdce vyvolat zvýšení tlaku v srdečních oddílech, případně dysfunkci baroreceptorů s následným vegetativním doprovodem. Během operace může velmi snadno dojít k narušení homeostázy neurovegetativního systému, z čehož vyplývá možnost vlivu perioperačního stresu na autonomní nervový systém. Přes četné studie stále ještě existuje holistický přístup k hodnocení odpovědi organismu na chirurgické výkony u pacientů podstupujících kardiochirurgické výkony. Obecně platí, že snížená HRV po kardiochirurgických výkonech se v pooperačním období během několika měsíců vrací k normálu. Tento článek je přehledem literatury s charakteristikami HRV u pacientů s defektem septa síní i její dynamiky po chirurgické a endovaskulární korekci defektu pod rentgenovou kontrolou. Článek rovněž upozorňuje na možnou patofyziologii uvedených abnormalit autonomního systému. ABSTRACTOver the recent decades, study of vegetative infl uence on the heart and its evaluation as a predictor of mortality due to cardiac problems and development of cardiovascular complications raised a considerable interest. Heart rate variability (HRV) analysis is a simple, noninvasive and safe method to study vegetative regulation of the human cardiovascular system. In the view of some authors, in patients suffering from structural heart defects, a decrease in HRV due to volume overload of the heart may cause elevation of pressure in the heart cavities, possible dysfunction of baroreceptors and can result in vegetative imbalance. During surgery, the neurovegetative homeostasis is extremely vulnerable that makes one think about the surgical stress infl uence on the autonomic nervous system. Despite numerous studies, there is still no holistic approach in determining the body response to surgical interventions in cardiosurgical patients. Generally, decreased heart rate variability after cardiac surgery gradually restores in the postoperative period within several months. This article is a literature review of the data on the characteristics of HRV in patients with atrial septal defect (ASD), as well as the regularities of its dynamics after surgical and X-ray endovascular correction of the defect. The article also highlights possible pathophysiology of these vegetative abnormalities.

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Heart rate variability improvement in children using transcatheter atrial septal defect closure

Cited by 8 publications

References 26 publications

Autonomic impairment of patients in coma with different Glasgow coma score assessed with heart rate variability

Autonomic impairment of patients in coma with different Glasgow coma score assessed with heart rate variability

Early changes in ambulatory electrocardiography after transcatheter closure in patients with atrial septal defect and factors affecting heart rate variability

Heart rate variability in atrial septal defect both before and after operation

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