Heart rate variability in chronic alcoholics: A follow-up study

Weise, F.; Müller, D; Krell, Dieter; Kielstein, Volker; Koch, R

doi:10.1016/0376-8716(86)90086-4

Cited by 30 publications

(20 citation statements)

References 6 publications

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“…Six other studies used 5 to 10 minutes of ECG recording in a supine or sitting position (Agelink et al, 1998;DePetrillo et al, 1999;Karimullah et al, 2001;Rechlin et al, 1996;Weise et al, 1985Weise et al, , 1986. Only 2 of 5 studies reported a recording time (DePetrillo et al, 1999;Karimullah et al, 2001).…”

Section: Studies Of Hrv In Alcohol-dependent Subjectsmentioning

confidence: 95%

“…They are only grossly comparable, however, since only 5 of 10 studies indicated that alcohol dependence was defined according to DSM-III R criteria (Agelink et al, 1998;DePetrillo et al, 1999;Karimullah et al, 2001;Rechlin et al, 1996) or DSM-IV criteria (Irwin et al, 2006). Six of 10 studies reported an average drinking length (between 3 and 40 years) and average daily alcohol consumption (100 to 350 g/d; Agelink et al, 1998;Irwin et al, 2006;Karimullah et al, 2001;Malpas et al, 1991;Weise et al, 1985Weise et al, , 1986. The remaining 4 studies provided only limited information on drinking history including duration of dependence (Rechlin et al, 1996), AUDIT scores (Sucharita et al, 2009), and clinical diagnosis (DePetrillo et al, 1999;Valladares et al, 2007).…”

Section: Studies Of Hrv In Alcohol-dependent Subjectsmentioning

confidence: 96%

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Characteristics of Heart Rate Variability in Alcohol-Dependent Subjects and Nondependent Chronic Alcohol Users

Karpyak

Romanowicz

Schmidt

et al. 2013

Alcohol Clin Exp Res

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Heart rate variability (HRV) is an objective and sensitive measure of integrated physiological functioning reflective of heart rhythm responsivity to internal and external demands. Reduced HRV is associated with vulnerability to stress and deterioration of medical and/or psychiatric conditions, while increased HRV is associated with a favorable treatment response and recovery from various medical and/or psychiatric conditions. Our previous review found that acute alcohol consumption caused decreased parasympathetic and increased sympathetic HRV effects in both nonalcoholic and chronic alcohol users. This review investigates the effects of chronic alcohol consumption on HRV in alcohol-dependent subjects and nondependent users. MEDLINE, Scopus, and PubMed were searched for human experimental and clinical trials that measured the effects of chronic alcohol use on HRV. Only publications that included a description of their study designs and clearly stated methodologies for data collections, and outcome measures were reviewed. We have reviewed a total of 24 articles. In nondependent users, low dose (approximating the recommended daily amount of 1 standard drink in women and 2 in men) use is associated with increased HRV parameters compared to those who drink less frequently or abstain altogether. A further increase in consumption is associated with decreased HRV compared to both abstainers and more moderate drinkers. HRV changes during withdrawal generally follow the same negative direction but are more complex and less understood. In dependent subjects, an improvement in HRV was seen following abstinence but remained reduced compared to nonalcoholic controls. This review demonstrates that HRV changes associated with chronic use follow a J-shaped curve. It supports recommendations that limit daily alcohol intake to no more than 2 drinks for men and 1 drink for women. Future studies should investigate HRV as a biomarker of alcoholism development and treatment response as well as the physiological basis for alcohol effects on HRV.

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Section: Studies Of Hrv In Alcohol-dependent Subjectsmentioning

confidence: 95%

Section: Studies Of Hrv In Alcohol-dependent Subjectsmentioning

confidence: 96%

Characteristics of Heart Rate Variability in Alcohol-Dependent Subjects and Nondependent Chronic Alcohol Users

Karpyak

Romanowicz

Schmidt

et al. 2013

Alcohol Clin Exp Res

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“…The present fi ndings suggest that HRV, as an active neurocardiac signaling process, may serve as a mechanistic link between unhealthy lifestyle choices and suboptimal cardiovascular control in emerging adulthood, reduced resilience to stress and emotional challenge, and potentially, increased risk for cardiovascular problems in the future. Suppression of HRV by health risk behaviors is modifi able, and basal HRV often rebounds on cessation of these behaviors (e.g., Castello et al, 2011;de Jonge et al, 2010;Lewis et al, 2010;Mouridsen et al, 2012;Munjal et al, 2009;Sjoberg et al, 2011;Sridhar et al, 2010;Weise et al, 1986). Thus, HRV may also be useful as a tool to objectively evaluate the positive effects of changes in lifestyle.…”

Section: Discussionmentioning

confidence: 99%

Potential Side Effects of Unhealthy Lifestyle Choices and Health Risks on Basal and Reactive Heart Rate Variability in College Drinkers

Udo

Mun

Buckman

et al. 2013

J. Stud. Alcohol Drugs

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ABSTRACT. Objective: Emerging adults often begin making independent lifestyle choices during college, yet the association of these choices with fundamental indicators of health and adaptability is unclear. The present study examined the relationship between health risks and neurocardiac function in college drinkers. Method: Heart rate variability (HRV) was assessed at baseline and in reaction to a paced breathing challenge in 212 college drinkers (53.8% women). Basal HRV served as a general indicator of health. Reactive HRV (during paced breathing) was used as a marker of an individual's adaptability to challenge. The relationship of HRV to alcohol use, cigarette use, exercise, sleep, and body mass index (BMI) was assessed. Results: Greater alcohol use and less exercise were associated with lower basal HRV. BMI was unrelated to basal HRV but was negatively associated with reactive HRV during the breathing challenge. Conclusions: High levels of alcohol use and lack of exercise are negative correlates of cardiovascular and general health, even in apparently healthy college drinkers. The negative relationship between BMI and reactive HRV suggests that overweight individuals have reduced ability to psychophysiologically adapt to challenges; understanding the temporal course of this relationship is needed. This study highlights the importance of examining HRV at baseline and in response to a challenge to capture the active neurocardiac processes that contribute to health and adaptive responding. The suppressive effects of health risks on HRV are modifi able; thus, HRV may be useful in evaluating the health benefi ts of lifestyle change and in promoting change behaviors in college drinkers. (J. Stud. Alcohol Drugs, 74, 787-796, 2013)

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“…Alcoholics also suffer damage to the autonomic nervous system [26], although presumably in a smaller proportion and to a lesser extent. The course of alcoholic neuropathy is thought to be favorable after cessation of drinking [20,44,48], however, prognostic implications have been reported [22]. Because of these differences it is desirable to determine the etiology of pathological findings in a given patient.…”

Section: Discussionmentioning

confidence: 99%

“…It may not be appropriate to generate an easily applicable algorithm to distinguish between these two causes of nerve damage by comparing the numbers of single symptoms, signs, and pathological findings between nonalcoholoic diabetics and nondiabetic alcoholics. The long interval between alcohol withdrawal and testing may lead to a reduced number of pathological results because mild alcoholic autonomic neuropathy may be quickly reversible [44,48]. However, in alcoholic patients a reliable examination of the sympathetic nervous system may be possible only after a longer period of abstinence, for example, 1 week [4,47] or even 6 weeks [8].…”

Section: Discussionmentioning

confidence: 99%

Differential diagnosis of neuropathic lesions in diabetic and alcoholic patients

Luft

Ob²,

Konz

et al. 1994

Clin Investig

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Cardiovascular reflex tests are used extensively to screen diabetic patients for autonomic cardiac neuropathy. Since alcohol abuse must often be considered the cause of nerve damage in internally ill patients, we examined 66 nonalcoholic type 1 (insulin-dependent) diabetics and 63 nondiabetic alcoholics matched for age, weight, and duration of disease to determine whether specific patterns of complaints, symptoms, signs, and results of the cardiovascular reflex tests can differentiate between alcoholic and diabetic nerve damages. In these carefully selected diabetic and alcoholic patients the medical history, clinical neurological assessment, and reflex test results all showed significant differences, resulting in different patterns which allow the correct allocation of nerve damage to either diabetic or alcoholic origin with easily available clinical means.

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Heart rate variability in chronic alcoholics: A follow-up study

Cited by 30 publications

References 6 publications

Characteristics of Heart Rate Variability in Alcohol-Dependent Subjects and Nondependent Chronic Alcohol Users

Characteristics of Heart Rate Variability in Alcohol-Dependent Subjects and Nondependent Chronic Alcohol Users

Potential Side Effects of Unhealthy Lifestyle Choices and Health Risks on Basal and Reactive Heart Rate Variability in College Drinkers

Differential diagnosis of neuropathic lesions in diabetic and alcoholic patients

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