Heart rate variability in rats with chronic hypoxic pulmonary hypertension

Fauchier, Laurent; Melin, Alexandre; Eder, Véronique; Antier, Daniel; Bonnet, Pierre

doi:10.1016/j.ancard.2006.01.005

Cited by 14 publications

(16 citation statements)

References 31 publications

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“…Furthermore, frequency-domain measurements (HF, LF, and TP) were all decreased compared to those in control patients. Our study findings were consistent with those of previous reports showing that HRV measurements were decreased in animal models 27,28 and clinical subjects 11,29,30 with PAH. Since RMSSD is used to evaluate short-term heart rate variation modulated by parasympathetic activity, it is possible that the parasympathetic modulation activity was impaired, leading to a reduced RMSSD in patients with IPAH.…”

Section: Autonomic Nervous System Function and Hrv In Ipah Patientssupporting

confidence: 95%

Heart rate variability parameters and ventricular arrhythmia correlate with pulmonary arterial pressure in adult patients with idiopathic pulmonary arterial hypertension

Hsieh

et al. 2014

Heart & Lung

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Section: Autonomic Nervous System Function and Hrv In Ipah Patientssupporting

confidence: 95%

Heart rate variability parameters and ventricular arrhythmia correlate with pulmonary arterial pressure in adult patients with idiopathic pulmonary arterial hypertension

Hsieh

et al. 2014

Heart & Lung

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“…8,20 -22 dog, 23,24 calf, 25 rabbit 26 and rat. 27,28 Results revealed that the values in rabbits and rats were quite different from those in humans. Heart rate was also completely different between human and rabbits or rats.…”

Section: Discussionmentioning

confidence: 96%

Comparative study of heart rate variability between healthy human subjects and healthy dogs, rabbits and calves

Manzo

Ootaki

et al. 2009

Lab Anim

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Several studies have been performed to assess heart rate variability (HRV) in several species such as humans, dogs, pigs, calves, rabbits and rats. However, haemodynamic parameters are totally different in each animal, and optimal animal models for studying HRV corresponding to human HRV are still unclear. The purpose of this study was to assess HRV in human subjects and to compare those HRV data with canine, bovine and rabbit HRV data. The heart rate in the human subjects (62.8 + 7.4 bpm) was significantly lower than that in dogs (124.2 + 18.8 bpm, P , 0.001), calves (73.4 + 10.5 bpm, P , 0.05), and rabbits (217.3 + 21.5 bpm, P , 0.001). The low-frequency waves (LF) (57.

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“…31 Similarly, a decreased heart variability in patients with primary pulmonary hypertension has also been reported. 32,33 In a recent interesting study, increased sympathetic nerve activity has been shown in PAH, suggesting that the mechanism may partially explained by chemo-reflex mediation.…”

Section: Discussionmentioning

confidence: 99%

Impairment of Autonomic Nervous System Activity in Patients With Pulmonary Arterial Hypertension: A Case Control Study

Dimopoulos¹,

Anastasiou-Nana²,

Katsaros³

et al. 2009

Journal of Cardiac Failure

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Heart rate variability in rats with chronic hypoxic pulmonary hypertension

Cited by 14 publications

References 31 publications

Heart rate variability parameters and ventricular arrhythmia correlate with pulmonary arterial pressure in adult patients with idiopathic pulmonary arterial hypertension

Heart rate variability parameters and ventricular arrhythmia correlate with pulmonary arterial pressure in adult patients with idiopathic pulmonary arterial hypertension

Comparative study of heart rate variability between healthy human subjects and healthy dogs, rabbits and calves

Impairment of Autonomic Nervous System Activity in Patients With Pulmonary Arterial Hypertension: A Case Control Study

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