Heart rate variability modifications following exercise training in type 2 diabetic patients with definite cardiac autonomic neuropathy

Pagkalos, M; Koutlianos, Nikos; Kouidi, Evangelia; Pagkalos, Emmanouil; Mandroukas, Konstantinos; Deligiannis, Asterios

doi:10.1136/bjsm.2007.035303

Cited by 90 publications

(84 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Heart rate variability, a measure of autonomic balance, improves as a result of exercise training (219,243), especially in those with autonomic disorders (243). Others have found that plasma noradrenaline decreases following training in heart failure patients.…”

Section: Green Et Al Exercise Hemodynamics and Vascular Adaptationmentioning

confidence: 99%

Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli

Green

Hopman

Padilla

et al. 2017

Physiological Reviews

530

570

View full text Add to dashboard Cite

On the 400 th anniversary of Harvey's Lumleian lectures, this review focusses on the impact of physical exercise on "hemodynamic" forces associated with the movement of blood through arteries in humans and the functional and structural adaptations that result from repeated episodic exposure to such stimuli. The late 20 th century discovery that endothelial cells modify arterial tone via paracrine transduction, provoked studies exploring the direct mechanical effects of blood flow and pressure on vascular function and adaptation in vivo. In this review, we address the impact of distinct hemodynamic signals that occur in response to exercise, the inter-relationships between these signals, the nature of the adaptive responses that manifest under different physiological conditions and the implications for human health.Exercise modifies blood flow, luminal shear stress, arterial pressure and tangential wall stress, all of which can transduce changes in arterial function, diameter and wall thickness.There are important clinical implications of the adaptation that occurs as a consequence of repeated hemodynamic stimulation associated with exercise training in humans, including impacts on atherosclerotic risk in conduit arteries, the control of blood pressure in resistance vessels, oxygen delivery and diffusion, and microvascular health. Exercise training studies have demonstrated that direct hemodynamic impacts on the health of the artery wall contribute substantially to the well-established decrease in cardiovascular risk attributed to physical activity.

show abstract

Section: Green Et Al Exercise Hemodynamics and Vascular Adaptationmentioning

confidence: 99%

Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli

Green

Hopman

Padilla

et al. 2017

Physiological Reviews

530

570

View full text Add to dashboard Cite

show abstract

“…This study found increases on SDNN, RMSSD, pNN50, LF ms2 and HF ms2 indexes, indicating benefits on autonomic modulation. The group with type 2 DM associated with CAN presented more significant improvements when compared to individuals with type 2 DM without CAN [19] . Regarding to the effects of physical training in type 2 DM with ischemic subclinical left ventricle dysfunction it was evaluated after a program of six months and there was increase in global HRV (TP and SDNN) but changes were not found in the parasympathetic modulation (RMSSD and HFms²).…”

Section: Methodsmentioning

confidence: 90%

“…Specially regarding to physical exercise, it may provide cardiovascular, metabolic and autonomic benefits in individuals with DM, leading to decreased insulin resistance and improved glycemic control in the blood [16] . Also, studies showed that physical exercise improves cardiac autonomic function in diabetic subjects [17,18,19] . In this context, to provide an update of published findings on the topic over the past thirteen years related to this issue and also given the matter of early identification and prevention of changes induced by DM on ANS, this review aimed at gather information about the influence of physical exercise on the ANS in individuals with DM, using HRV as a tool.…”

Section: Discussionmentioning

confidence: 99%

Influence of the Exercise on Autonomic Nervous System in Diabetics: A Literature Review

Giacon

Vanderlei

Silva

et al. 2017

Journal of Cardiology and Therapy

View full text Add to dashboard Cite

“…Improvement of autonomic nerve function following regular physical exercise have been reported in healthy adolescent and in working class and also in menopause [6][7][8][9][10][11][12][13] .…”

Section: Introductionmentioning

confidence: 99%

Effect of Physical Exercise on Autonomic Nerve Function in Irritable Bowel Syndrome

Tenzina

Begum

Ferdousi

2015

J Bangladesh Soc Physiol

View full text Add to dashboard Cite

Background: Irritable bowel syndrome (IBS) may be associated with autonomic nerve dysfunction. However, moderate to vigorous physical exercise cause improvement of this nerve function. Objective: To observe the effect of moderate physical exercise on the autonomic nerve activity by analysis of HRV in patients with Irritable bowel syndrome. Methods: This prospective study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka in 2013. For this purpose, 77 male patients aged 20-50 years with IBS were included in the study. They were subdivided into IBS-D (24 patients), IBS-C (26 patients) and IBS-A (27 patients) and were selected from the OPD, Gastroenterology, BSMMU. 28 apparently healthy male were studied as control. HRV parameters were recorded prior to onset of physical exercise and after completion of 3 months of brisk walking. For assessing autonomic nerve function, some time domain measures of HRV were recorded by Polyrite D. ANOVA, Independent sample t-test and paired t-tests were used for statistical analysis. Results: The pre-exercise values of mean R-R interval, Max/Min ratio, SDNN,RMSSD, NN50%, PNN50% were significantly(p<0.05) lower and mean heart rate was significantly (p<0.05) higher in all IBS patients compared to control. The post exercise data showed mean HR was significantly decreased in IBS-A and SDNN & RMSSD were significantly increased in IBS-C and IBS-A. Conclusion: This study concluded that parasympathetic activity decreased in patients with IBS, which was improved after regular moderate physical exercise of 3 months.

show abstract

Heart rate variability modifications following exercise training in type 2 diabetic patients with definite cardiac autonomic neuropathy

Abstract: The results indicate that 6-month aerobic exercise training improves the cardiac autonomic nervous system function in type 2 diabetic patients. However, more favourable effects are found in type 2 diabetic patients with definite CAN.

Cited by 90 publications

References 46 publications

Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli

Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli

Influence of the Exercise on Autonomic Nervous System in Diabetics: A Literature Review

Effect of Physical Exercise on Autonomic Nerve Function in Irritable Bowel Syndrome

Contact Info

Product

Resources

About