“…Among them, septicemia followed by cardiovascular problems (including cerebrovascular disease) is a common cause of fatalities and, according to a recent large study significantly more common among patients with PV than in the general population (Huang et al , 2012). Interestingly, growing evidence suggests that patients who were exposed to dosages of glucocorticoids greater than the equivalent of 7.5 mg of prednisolone per day during 1–5 years of follow‐up had substantially higher rates of all cardiovascular diseases, including myocardial infarction, heart failure, and cerebrovascular disease ((Wei et al , 2004). Unfortunately, available data are too patchy (Table 3) to determine which treatment constitutes the major risk, despite a general belief that adjuvant therapies have decreased PV mortality.…”