“…At the lower pulse fluence of 1.1 J/cm 2 , coagulation was observed to extend deeper than at 1.4 J/cm 2 . This finding has been predicted theoretically for the ablation regime [7,8,21] and can be explained by the reduced ablation efficiency at lower fluences, which results in a larger deposition of heat in tissue underneath the ablation crater. This effect is most likely exaggerated by thermal buildup during the high-repetition-rate irradiation sequence, which desiccates the tissue between subsequent laser pulses and deprives it of the main chromophore for Er:YAG laser radiation [11].…”