Heat dissipation mechanism of magnetite nanoparticles in magnetic fluid hyperthermia

Suto, Makoto; Hirota, Yasutake; Mamiya, Hiroaki; Fujita, Akira; Kasuya, Ryo; Tohji, Kazuyuki; Jeyadevan, Balachandran

doi:10.1016/j.jmmm.2009.02.070

Cited by 178 publications

(124 citation statements)

References 16 publications

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“…The physical, magnetic and heating characteristics of magnetite nanoparticle suspensions with average diameters of 12.5 and 15.7 nm were discussed in detail by Suto et. al [53]. They highlighted the relative contributions of Neel and Brownian relaxations on magnetic heat dissipation and reported that the specific absorption rates (SAR) dropped by 27% for the 12.5 nm particles and by 67% for the 15.7 nm particles, by suppressing the particle rotation (via dispersion of magnetite nanoparticles in hydro-gel).…”

Section: Experimental/theoretical Modelling Studies Of Magnetic Nanopmentioning

confidence: 99%

A review on hyperthermia via nanoparticle-mediated therapy

et al. 2017

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Section: Experimental/theoretical Modelling Studies Of Magnetic Nanopmentioning

confidence: 99%

A review on hyperthermia via nanoparticle-mediated therapy

et al. 2017

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“…Consequently, the author proposed the use of effective specific absorption rate (ESAR) values that were calculated using the equation given below taking the magnetic field strength and frequency into consideration. 17) Theoretical estimation of ESAR values as a function of particle diameter (maximum of 18 nm), assuming a harmonic mean value for the relaxation time of 2.6 © 10 ¹7 s is calculated according to Eq. (6):…”

Section: )mentioning

confidence: 99%

“…For example, decision whether the ac magnetic field generators should be designed with higher magnetic field strength or higher frequencies has to be made. Thus here 12, 14 and 16 nm magnetite particles with effective magnetic anisotropy energy of 30 kJ/m 3 (H k 107 kA/m) are considered based on the recently reported experimental data 17) and their results are discussed. As stated above, since the Brownian relaxation is influenced mainly by the local conditions, heat dissipation through Néel relaxation alone is considered here.…”

Section: )mentioning

confidence: 99%

Present status and prospects of magnetite nanoparticles-based hyperthermia

Jeyadevan

2010

J. Ceram. Soc. Japan

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Magnetic fluid hyperthermia is a cancer treatment technique that utilizes the heat dissipated by magnetic nanoparticles exposed to an alternating current magnetic field. The heat dissipated is consequence of the conversion of the magnetic energy through different relaxation mechanisms, which depends on the physical properties of the magnetic particles. Particularly, in the case of magnetic nanoparticles, the magnetic energy is converted to heat energy either by the resistive response of the rotation of the magnetic particles (Brownian relaxation) or the rotation of the magnetic moment within the particles (Néel relaxation) to the alternating magnetic field. In this article, the main focus has been on the progress of theoretical and experimental investigations towards the realization of magnetic fluid hyperthermia (MFH) through heat dissipation by Néel relaxation of magnetite particles. We discuss about the present status and prospects of magnetite nanoparticles-based hyperthermia focusing mainly on the dissipation of heat through Néel relaxation mechanism. In doing so, an attempt has been made to review and deepen the understanding on specific topics such as (a) specific heat absorption characteristics of magnetite, especially the physical properties of particles that generate heat through Néel relaxation, (b) the preparation techniques available to synthesize particles with required properties, (c) experimental investigations carried out to determine the relative contribution of Néel relaxation to dissipate heat and their potential for in vivo application, and (d) the theoretical estimation of and experimental verification of heat diffusion characteristics of magnetite. The theoretical and experimental studies have suggested that the development of case specific treatment technologies based on an integrated approach considering both the physical constraints of the magnetic particles to be used as thermal seeds and practically feasible alternating magnetic field generators is a must for the establishment of MFH therapy in the foreseeable future.

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“…This suggests the appearance of superparamagnetism with increasing temperature, which agrees with VSM measurements. C. Our study suggests that the precursor injection time during the hot-injection process cleary affects the nanoparticle size, which leads to the changes in the total magnetization and conversion of magnetic energy into thermal energy by Neel and Brownian relaxations losses [13].…”

Section: Resultsmentioning

confidence: 85%

Hyperthermia Properties of Fe₃O₄Nanoparticle Synthesized by Hot-injection Polyol Process

Lee¹,

Kouh²,

Shim³

et al. 2014

Journal of the Korean Magnetics Society

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The Fe 3 O 4 nanoparticle was synthesized by the hot-injection method while varying the injection time of the precursor solution. The crystal structure was determined to be cubic inverse spinel with space group of Fd-3m based on X-ray diffraction (XRD) measurements and the morphology of the prepared Fe 3 O 4 nanoparticle was studied with a high-resolution transmission electron microscope (HR-TEM). When the precursor solution was injected for 0.5 min, the size of the Fe 3 O 4 nanoparticle was 7.63 nm, while the size of the obtained particle was 21.27 nm with the injection time of 60 min. The magnetic properties of the prepared Fe 3 O 4 nanoparticle were investigated by both vibrating sample magnetometer (VSM) and 57Co Mössbauer spectroscopy at various temperatures. From the hyperthermia measurement, we observed that the temperature of the Fe 3 O 4 nanoparticle powder reached around 120 o C under 250 Oe at 50 kHz, when the injection time of the precursor solution was 60 min.

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Heat dissipation mechanism of magnetite nanoparticles in magnetic fluid hyperthermia

Cited by 178 publications

References 16 publications

A review on hyperthermia via nanoparticle-mediated therapy

A review on hyperthermia via nanoparticle-mediated therapy

Present status and prospects of magnetite nanoparticles-based hyperthermia

Hyperthermia Properties of Fe₃O₄Nanoparticle Synthesized by Hot-injection Polyol Process

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Heat dissipation mechanism of magnetite nanoparticles in magnetic fluid hyperthermia

Cited by 178 publications

References 16 publications

A review on hyperthermia via nanoparticle-mediated therapy

A review on hyperthermia via nanoparticle-mediated therapy

Present status and prospects of magnetite nanoparticles-based hyperthermia

Hyperthermia Properties of Fe3O4Nanoparticle Synthesized by Hot-injection Polyol Process

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Hyperthermia Properties of Fe₃O₄Nanoparticle Synthesized by Hot-injection Polyol Process