Heat sensitive E-helix cut ferritin nanocages for facile and high-efficiency loading of doxorubicin

Xia, Haining; Xu, Huangtao; Wang, Jiarong; Wang, Changhao; Chen, Ruiguo; Tao, Tongxiang; Xu, Shuai; Zhang, Jing; Ma, Kun; Wang, Junfeng

doi:10.1016/j.ijbiomac.2023.126973

International Journal of Biological Macromolecules

2023

DOI: 10.1016/j.ijbiomac.2023.126973

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Heat sensitive E-helix cut ferritin nanocages for facile and high-efficiency loading of doxorubicin

Haining Xia,

Huangtao Xu,

Jiarong Wang

et al.

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2024

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Cited by 2 publications

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Preparation and brain targeting effects study of recombinant human ferritin nanoparticles

Wang,

Xu,

Zhu

et al. 2024

Biochemical and Biophysical Research Communications

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Preparation and brain targeting effects study of recombinant human ferritin nanoparticles

Wang,

Xu,

Zhu

et al. 2024

Biochemical and Biophysical Research Communications

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A New Age of Drug Delivery: A Comparative Perspective of Ferritin–Drug Conjugates (FDCs) and Antibody–Drug Conjugates (ADCs)

Hong,

Li,

et al. 2024

Bioconjugate Chem.

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Ferritin–drug conjugates (FDCs) and antibody–drug conjugates (ADCs) respectively represent the innovative and traditional mainstream approaches in drug delivery systems, each offering unique advantages and challenges. This viewpoint delves into the evolving landscape of drug delivery technologies, specifically focusing on FDCs and ADCs. Each method exhibits unique advantages and inherent challenges, shaping their roles in therapeutic applications. The article provides a comparative analysis of two delivery systems, FDCs and ADCs, in terms of targeting accuracy, drug loading capacity, and the nature of the payload itself. This comparison offers valuable insights into the distinct advantages and disadvantages associated with each system, enabling a clearer understanding of their potential applications and limitations in therapeutic contexts. This analysis is crucial for optimizing the use of these delivery systems across varying medical contexts, offering a comprehensive overview of their impact on the field of drug delivery.

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Heat sensitive E-helix cut ferritin nanocages for facile and high-efficiency loading of doxorubicin

Cited by 2 publications

References 54 publications

Preparation and brain targeting effects study of recombinant human ferritin nanoparticles

Preparation and brain targeting effects study of recombinant human ferritin nanoparticles

A New Age of Drug Delivery: A Comparative Perspective of Ferritin–Drug Conjugates (FDCs) and Antibody–Drug Conjugates (ADCs)

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