Heat stress decreases plasma vitamin C concentration in lactating cows

Padilla, L.; Matsui, Tohru; Kamiya, Yuko; Kamiya, Mitsuru; Tanaka, Masahito; Yano, Hideo

doi:10.1016/j.livprodsci.2005.12.002

Cited by 66 publications

(56 citation statements)

References 15 publications

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“…However, the averaged plasma vitamin C concentration was markedly lower in the above report than in the other reports using dairy cows [5,15,25]. It was postulated that some factors decreased plasma vitamin C concentration in the cows that we used.…”

Section: Discussioncontrasting

confidence: 61%

“…Furthermore, the plasma vitamin C concentration differed largely among the cows (ranged from 6 to 28 µM) and the plasma vitamin C concentration was lower than 10 µM in 17 cows of 118 cows (Unpublished data). Although the reference level of plasma vitamin C concentration has not been clarified, the plasma vitamin C concentration in healthy lactating cows is 19µM in the report of Weiss [25] or 20 µM in the report of Hidiroglou [5] and Padilla et al [15]. Therefore, it was postulated that some factors decreased plasma vitamin C concentration in the cows that we used previously [14].…”

mentioning

confidence: 90%

“…Domestic animals have not been considered to require dietary vitamin C because they can synthesize a sufficient amount of ascorbic acid (AsA) in the liver [10]. However, the plasma vitamin C concentration was decreased in the calves stressed by housing conditions [2], and in the lactating cows with mastitis [26] and exposed to heat stress [15]. Furthermore, a clinical case of scurvy, i.e., a typical sign of vitamin C deficiency was reported in cows [3].…”

mentioning

confidence: 99%

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Relationship between Plasma Vitamin C and Serum Diagnostic Biochemical Markers in Lactating Cows

Padilla

Matsui

Shibano³

et al. 2007

The Journal of Veterinary Medical Science

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ABSTRACT. We investigated the relationship between plasma vitamin C concentration and serum levels of some diagnostic biochemical markers in 118 lactating Holstein cows. Blood sample was collected once from each cow and we measured the plasma vitamin C concentration and the serum levels of glucose, β-hydroxybutyrate, free fatty acids, triacylglycerol, total cholesterol, albumin, total bilirubin, alkaline phosphatase, aspartate aminotransferase and γ-glutamyltransferase. The regression of plasma vitamin C with each serum diagnostic biochemical marker indicated that the vitamin C concentration significantly decreased as glucose, alkaline phosphatase or aspartate aminotransferase level increased and as total cholesterol or albumin concentration decreased. Furthermore, the plasma vitamin C concentration was significantly lower in the cows showing that each of these marker levels was out of its reference interval than in the cows showing that the marker level was within its reference interval. The significant correlations were observed among total cholesterol, albumin, alkaline phosphatase and aspartate aminotransferase levels, to which the glucose concentration was not related. These results showed that the plasma vitamin C concentration was low in the cows that had concurrently low levels of total cholesterol and albumin, and high levels of alkaline phosphatase and aspartate aminotransferase. Therefore, a hepatic malfunction possibly decreases plasma vitamin C concentration through suppressing vitamin C production. On the other hand, the high level of glucose possibly decreases plasma vitamin C concentration through suppressing vitamin C recycling. KEY WORDS: dairy cows, diagnostic biochemical marker, vitamin C.

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Section: Discussioncontrasting

confidence: 61%

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confidence: 90%

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confidence: 99%

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Relationship between Plasma Vitamin C and Serum Diagnostic Biochemical Markers in Lactating Cows

Padilla

Matsui

Shibano³

et al. 2007

The Journal of Veterinary Medical Science

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“…Other metabolic changes have been reported: an increase in serum prolactin which affects follicle development negatively; a drop in plasma vitamin C, an anti-oxidant which contributes in protection of the young embryo [16,17] decrease of triiodothyronine and thyroxine [3]; respiratory alkalosis; urine excretion of bicarbonate; base-excess reduction; loss of serum potassium; hyperventilation [7].…”

Section: Negative Effects Of Heat Stress On Dairy Cattlementioning

confidence: 99%

Heat Stress in Dairy Cattle: Major Effects and Practical Management Measures for Prevention and Control

Noordhuizen¹

2015

SOJVS

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SOJ Veterinary SciencesOpen Access Review Article ways by which animals can get rid of their thermal body load: conduction, convection, radiation ( Figure 1). In the zone I-III the animal can maintain a constant body temperature; in zone I-II and zone II-III heat production and heat loss is regulated. In zone I-II, heat production increases in order to maintain homeostasis. Zone II-III is the thermo-neutral zone, where heat loss is kept constant. Factors other than climate (e.g. ration, milk yield level, activity) determine the heat production in that zone [2]. The temperature points II and III are the lower and upper critical temperatures respectively, beyond which cold stress and heat stress respectively occur.When temperature increases beyond a given critical limit, the non-evaporative ways of heat loss appear to be far less efficient. And if temperature rises even more, the cow changes from a non-evaporative to an evaporative way. However, the latter is strongly dependant on the level of air humidity.The thermo-neutral zone of dairy cows in full lactation is, roughly speaking, between -5°C and +20°C for adult dairy cows AbstractOver the past years we have experienced several periods of heat waves, sometimes of short, other times of longer duration. This phenomenon will, most probably, be more frequent in the years to come. Heat waves may have detrimental effects on cattle production, health, welfare and reproduction. The question is whether cattle farmers and even veterinarians are sufficiently prepared and instructed to counteract or, even better, prevent the negative effects of heat stress in their cattle. This paper reviews the most relevant issues associated with the occurrence of heat stress, and provides practical measures to counteract and prevent the negative effects of heat stress in cattle.

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“…The plasma vitamin C level in cattle declines during heat stress (Padilla et al 2006). Few research reports also document the beneficial effects of Vitamin C supplementation in goats (Kobeisy 1997;Sivakumar et al 2010).…”

Section: Heat Stressmentioning

confidence: 99%

L-Ascorbic acid (vitamin C) supplementation to optimize health and reproduction in cattle

Ranjan

et al. 2012

Veterinary Quarterly

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Cattle can synthesize L-ascorbic acid (or Vitamin C) from either D-glucose or D-galactose through glucuronic acid pathway in the liver. L-Ascorbic acid present in cattle diet is almost totally destroyed by rumen microorganisms making them essentially dependent on its endogenous synthesis, which is assumed sufficient to meet the physiological requirement. Therefore, the role of vitamin C in cattle health and disease has remained widely overlooked. However, there is mounting evidence that the level of L-ascorbic acid in blood and other tissues decreases in association with stress and disease, and Vitamin C supplementation revealed favorable response as evident from early recovery. The present review is an attempt to summarize the existing literature pertaining to the physiological role of L-ascorbic acid and the scope of its supplementation in the prevention and treatment of diseases in cattle. It should be realized that the aqueous solution of vitamin C is highly acidic and subcutaneous or intramuscular administration may cause tissue irritation and inflammation, whereas the sodium ascorbate solution is less acidic and might be used for intramuscular administration.

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Heat stress decreases plasma vitamin C concentration in lactating cows

Cited by 66 publications

References 15 publications

Relationship between Plasma Vitamin C and Serum Diagnostic Biochemical Markers in Lactating Cows

Relationship between Plasma Vitamin C and Serum Diagnostic Biochemical Markers in Lactating Cows

Heat Stress in Dairy Cattle: Major Effects and Practical Management Measures for Prevention and Control

L-Ascorbic acid (vitamin C) supplementation to optimize health and reproduction in cattle

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