A simple analytical model of a Differential Pressure Swing Adsorption (DPSA) process on a single adsorbent particle was used to evaluate the effects of gas-solid heat transfer resistance on the cyclic working capacity of the particle. The commonly used assumption of instantaneous thermal equilibrium between the gas and the adsorbent inside an adsorber may not be valid when the gas flow rates are low, the adsorption kinetics is relatively fast, and the PSA cycle times are small.