“…In order to obtain crystal structures of anhydrous compounds, a novel approach is required where intervention of solvent can be entirely eliminated. There are a large number of methods to synthesize single crystals of a required compound like for example slow evaporation, vapor diffusion, solvent diffusion, sublimation, convection, and zonemelting. − Out of these techniques, slow evaporation from a solution is frequently adopted to grow single crystals of organics, and frequently this process leads to the incorporation of the solvent in the crystal structure. For example, adenine always crystallizes with the incorporation of three water molecules during crystallization.…”