While thermal convection cells exhibit left–right and top–bottom symmetries at low Rayleigh numbers (Ra), the emergence of coherent flow structures, such as elliptical large-scale circulation in Rayleigh–Bénard convection (RBC), breaks these symmetries as the Rayleigh number increases. Recently, spatial double-reflection symmetry was proposed and verified for two-dimensional RBC at a Prandtl number of 6.5 and Ra values up to 1010. In this study, we examined this new symmetry at a lower Prandtl number of 0.7 and across a wider range of Rayleigh numbers, from 107 to 1013. Our findings reveal that the double-reflection symmetry is preserved for the mean profiles and flow fields of velocity and temperature for Ra<109, but it is broken at higher Rayleigh numbers. This asymmetry at high Ra values is inferred to be induced by a flow-pattern transition at Ra=109. Together with the previous study, our results demonstrate that the Prandtl number has an important influence on the symmetry preservation in RBC.