Flow and heat transfer profiles in a square channel heat exchanger inserted with 45° V-orifices are presented. The influences of Reynolds number (Re = 3000-10,000) and blockage ratio (BR = 0.05, 0.10, 0.15, 0.20 and 0.25) on periodic concepts are investigated numerically. The computational domain is solved with the finite volume method and SIMPLE algorithm. As the numerical results, the periodic profiles on flow and heat transfer are found when inserted the 45° Vorifices in the square duct. The configurations on flow and heat transfer in the heating section can separated into two sections; periodic profile and fully developed periodic profile. The patterns on flow and heat transfer are similar, but the values are not equal, called "periodic profiles", while the identical on both profiles and values, called "fully developed periodic profiles". In addition, the periodic structures depends on the parameters of the vortex generator, position in the channel and Reynolds number.