Barocaloric cooling is classified as environmentally friendly because of the employment of solid-state materials as refrigerants. The reference and well-established processes are based on the active barocaloric regenerative refrigeration cycle, where the solid-state material acts both as refrigerant and regenerator; an auxiliary fluid (generally water of water/glycol mixtures) is used to transfer the heat fluxes with the final purpose of subtracting heat from the cold heat exchanger coupled with the cold cell. In this paper, we numerically investigate the effect on heat transfer of working with nanofluids as auxiliary fluids in an active barocaloric refrigerator operating with a vulcanizing rubber. The results reveal that, as a general trend, adding 10% of copper nanoparticles in the water/ethylene-glycol mixture carries to +30% as medium heat transfer enhancement.Energies 2019, 12, 2902 2 of 15 effects (ECE) [20][21][22], and mechanical fields provoke elastocaloric (eCE) [23] or barocaloric effects (BCE) [24], respectively, as consequences of stretching or of hydrostatic pressure application.Caloric cooling is classified as environmentally friendly because it employs solid-state materials as refrigerants that do not directly impact global warming since they do not disperse in the atmosphere, as confirmed by a certain number of investigations [25][26][27][28] that asserted the eco-friendliness of all the techniques belonging to magneto- [29,30], electro-[31,32], elasto-[33,34], and baro-caloric [35] cooling.The reference and well-established systems for caloric cooling are based on the active caloric regenerative refrigeration (ACR) cycle, a thermodynamic Brayton-based cycle in which the caloric solid-state material acts as both the refrigerant and the regenerator, thus recovering heat fluxes through the help of an auxiliary fluid that vehiculates them with the final purpose of subtracting heat from the cold heat exchanger (and therefore the cold environment) [36]. To improve the efficiency of a caloric cooler, the ACR system works with the optimal operative parameters (such as the geometry of the regenerator, the fluid velocity, and the frequency of the cycle) [37-39] but the bottleneck is employing materials due of high caloric effect in the temperature range toward the application is devoted to [40]. A very wide "chapter" is currently open in the research panorama regarding the efforts to realize suitable caloric effect materials. A huge number of studies have been conducted over the last decades, and several promising materials have been identified for each specific caloric technique [41][42][43].Magnetocaloric is the most mature solid-state cooling technique [44,45], as it was the first to be investigated; however, there are still inherent limitations and holdups in creating high-intensity magnetic fields by permanent magnet application [46,47]. More recently, electrocaloric and elastocaloric techniques have gained interest in the scientific community-certain objectives are being reached, and many prototypes...