The key purpose of this article is to examine magnetohydrodynamics flow, generative/absorptive heat, and mass transfer of nanofluid flow past a wedge in the presence of viscous dissipation through a porous medium. The investigation is completely theoretical, and the present model expresses the influence of Brownian motion and thermophoresis using the nanofluid Buongiorno model. The fundamental model of partial differential equations is reframed into the structure of ordinary differential equations implementing the nondimensional similarity transformation, which are tackled through the fourth–fifth‐order Runge–Kutta–Fehlberg algorithm together with the shooting scheme. The analysis of sundry nondimensional controlling parameters, such as magnetic parameter, Eckert number, heat generation/absorption parameter, porosity parameter, Brownian motion parameter, and thermophoresis parameter on velocity, temperature, and concentration profiles are discussed graphically. The effects of the physical factors on the rate of momentum and heat and mass transfer are also determined with appropriate analysis in terms of skin friction, Nusselt number, and Sherwood number. The outcomes illustrate that the local Nusselt number and local Sherwood number are reduced for higher values of the thermophoresis parameter. Besides, it is found that higher estimations of heat generation/absorption and viscous dissipation parameters increase temperature. Moreover, it is found that the temperature profile increases with the involvement of the Brownian motion parameter, while an opposite trend is observed in the concentration profile. A comparison is also provided for limiting cases to authenticate our obtained results.