Blood arteries are important part of our cardiovascular system. A comprehensive study of shape and anatomy of blood arteries allows to elucidate the dynamics of blood flow in these arteries. Typically, the arteries are a curved-tube like structure, with arterial walls exhibiting a composition of various porous layers. The current study embarks on a theoretical exploration of a two-fluid model of blood flow and heat transfer through the curved artery under an influence of a magnetic field. The artery walls are composed of Brinkman and Darcy layers. The blood flows through a curved artery exerts centrifugal forces on the arterial walls that leads to change the blood flow patterns. The significant effects of curvature along with the intensity of an applied magnetic field on the blood flow patterns, heat transfer, and resistance impedance in curved artery have been investigated in the present work. The mathematical model of the proposed work is tackled by the homotopy analysis method using physically relevant boundary and interface conditions. The significant outcome of the present work is that the heat transfer rate increases with the increase in the curvature parameter, and it reduces on raising the couple stress parameter and Hartmann number. The novelty of this work lies in the consideration blood flow and heat transfer in inner endothelial layers of curved porous artery. The result presented in this work is vital to assess the condition of atherosclerosis, aneurysms, vasculties, blood clot, etc.; beyond this, the present model can be extended for medical diagnostics, treatment planning, medical device design, drug delivery optimization, and biomedical engineering research. This study can ultimately contribute for improved patient care and outcomes in cardiovascular medicine.