Open-cell foams are attractive for heat transfer enhancement in many engineering applications. Forced pulsations can lead to additional heat transfer enhancement in porous media. Studies of heat transfer in open-cell foams under forced pulsation conditions are limited. Therefore, in this work, the possibility of heat transfer enhancement in porous media with flow pulsations is studied by a numerical simulation. To generate the 3D open-cell foams, the Laguerre–Voronoi tessellation method was used. The foam porosity was 0.743, 0.864, and 0.954. The Reynolds numbers ranged from 10 to 55, and the products of the relative amplitude and the Strouhal numbers ranged from 0.114 to 0.344. Heat transfer was studied under the conditions of symmetric and asymmetric pulsations. The results of numerical simulation showed that an increase in the amplitude of pulsations led to an augmentation of heat transfer for all studied porosities. The maximum intensification of heat transfer was 43%. Symmetric pulsations were more efficient than asymmetric pulsations, with Reynolds numbers less than 25. The Thermal Performance Factor was always higher for asymmetric pulsations, due to the friction factor for symmetrical pulsations being much higher than for asymmetric pulsations. Based on the results of a numerical simulation, empirical correlations were obtained to predict the heat transfer intensification in porous media for a steady and pulsating flow.