Heated Tobacco Product Smokers in Japan Identified by a Population-Based Survey

Kinjo, Aya; Kuwabara, Yuki; Fujii, Maya; Imamoto, Aya; Osaki, Yoneatsu; Minobe, Ruriko; Maezato, Hitoshi; Nakayama, Hideaki; Takimura, Tsuyoshi; Higuchi, Susumu

doi:10.2188/jea.je20190199

Cited by 25 publications

(29 citation statements)

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“…The prevalence of current HTP users among Korean adults reached 4.4.% a year after its introduction in Korea—a much higher rate than those of Italy, United States, or Great Britain, but similar to Japan’s 4 - 7 . Although this confirmed that HTPs are relatively more popular in East Asian countries, it should be interpreted cautiously, as their introduction time is different for various countries.…”

Section: Discussionmentioning

confidence: 93%

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Prevalence and correlates of current use of heated tobacco products among a nationally representative sample of Korean adults: Results from a cross-sectional study

Kim¹,

Cho²

2020

Tob. Induc. Dis.

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Heated tobacco products (HTPs) release aerosols containing nicotine and toxic chemicals upon heating of the tobacco without combustion 1. IQOS was introduced in 2014 and is now available in 51 countries 2. HTPs were introduced in Korea in June 2017 and their market share increased rapidly; in 2019, they accounted for 10.5% of the total tobacco in the country 3. The rate of current HTP use was 5.0% among Japanese adults in 2018 4. In 2017, 1.4% of Italian adults were ever users of HTPs 5. However, in countries where their sale started later, the proportion of adult users was lower. As of 2017, there were 0.8% current users in Great Britain 6 and 1.1% in the United States 7 , where IQOS had been available since 2016 and 2019, respectively. In Korea, the prevalence of HTP use was 3.5% in 2017 8 , and 2.13% in 2018 9. Philip Morris International claimed that switching completely from combustible cigarettes (CCs) to IQOS would reduce health risk 10. However, most HTP users used CCs or/and electronic cigarettes (ECs) rather than switching to HTPs completely 6-9. According to independent studies, the levels of some harmful and potentially harmful constituents of HTPs were lower than those of CCs 10,11. Nevertheless, the longterm effects of HTPs on individual-or populationlevel health are yet to be determined. According to a recent study, CC users who had used HTPs were ABSTRACT INTRODUCTION Heated tobacco product (HTP) use has increased rapidly in Korea since its introduction in 2017. We investigated the prevalence and correlates of the current use of HTPs among a nationally representative sample of Korean adults. METHODS A total of 6182 participants aged ≥19 years took part in the 2018 Korea National Health and Nutrition Examination Survey conducted one year after the introduction of HTPs in Korea. Descriptive statistics, bivariate analysis and multivariable logistic regressions were used. RESULTS The prevalence of current HTP use (defined as past 30-day use) among Korean adults was 4.4% (7.8% for males and 0.9% for females) in 2018. Among current HTP users, approximately 90% were dual users with combustible cigarettes (CCs) or electronic cigarettes (ECs), or triple users with CCs and ECs. In multivariable logistic regression analysis, males, younger participants, and current CC and/or EC users showed greater odds of being current users of HTPs compared with females, older participants, and non-users of CCs and ECs. Moreover, current EC-only users were more likely to use HTPs than current CC-only users. Compared with current CC-only use, using HTPs with CCs concurrently was not associated with attempts to quit smoking during the past year or with intentions to quit CC smoking. CONCLUSIONS The popularity of HTP use and the pattern of its poly use with CCs and ECs is a new challenge for Korean tobacco control policy.

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Section: Discussionmentioning

confidence: 93%

“…The rate of current HTP use was 5.0% among Japanese adults in 2018 4 . In 2017, 1.4% of Italian adults were ever users of HTPs 5 .…”

Section: Introductionmentioning

confidence: 99%

Prevalence and correlates of current use of heated tobacco products among a nationally representative sample of Korean adults: Results from a cross-sectional study

Kim¹,

Cho²

2020

Tob. Induc. Dis.

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“…Among adult women, those who were 20-39 years old, with 15 or fewer years of education, with a household size of three or more people, employed or self-employed, current internet users, and with risky behaviors related to alcohol were more likely to use HTPs. 40) 1945 1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 Another Japanese study compared device preference and showed that IQOS was used more by younger people and those who reported daily use. 41) Dunbar et al 42) reported that among young adults in the United…”

Section: Characteristics Of Heated Tobacco Product Usersmentioning

confidence: 99%

“…In one Japanese study, the prevalence of HTP use among adult men was highest among the following groups: individuals aged 20–49 years old, with 10 or more years of education, who were not bereaved or divorced, with high household income, who were current internet users, and with risky behaviors related to alcohol. Among adult women, those who were 20–39 years old, with 15 or fewer years of education, with a household size of three or more people, employed or self-employed, current internet users, and with risky behaviors related to alcohol were more likely to use HTPs [ 40 ]. Another Japanese study compared device preference and showed that IQOS was used more by younger people and those who reported daily use [ 41 ].…”

Section: Trends In Tobacco Use In South Koreamentioning

confidence: 99%

The Impact of Heated Tobacco Products on Smoking Cessation, Tobacco Use, and Tobacco Sales in South Korea

Lee

2020

Korean J Fam Med

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Heated tobacco products (HTPs), a hybrid between conventional and electronic cigarettes, were first launched in South Korea in June 2017. Owing to advertisements stating that HTPs are odorless, tar-free, and less harmful to health, the sales of HTPs have grown quickly enough to account for about 10% of the total tobacco market in a year. HTP use by young, highly educated, and high-income groups had a significant impact on both the overall tobacco market over the past 3 years and the smoking and quitting behaviors of smokers. Based on national smoking rate statistics, tobacco sales trends, and the number of visitors to smoking cessation clinics, the following changes have been identified: (1) The decline in current smoking rates has slowed or rose in some groups. (2) The decline in total cigarette sales has slowed but rose again in the first quarter of 2020. (3) The number of visitors to smoking cessation clinics decreased just after the advent of HTPs. These results may be due to the insufficient support of tobacco regulation policies but also coincide chronologically with the appearance of HTPs in South Korea. It is necessary to investigate the usage rate of various tobacco products, including HTPs and e-cigarettes, to examine the health risks of novel tobacco products and provide accurate information to users and policymakers. Finally, tobacco companies are continuously developing new product concepts to escape the regulation of existing cigarettes; thus, comprehensive management measures for all nicotine-containing products are needed.

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“…Furthermore, Jiang et al showed that miR-21 peripheral blood levels are increased in atherosclerosis, suggesting its potential as a biomarker for CVD 18 . In addition, miR-21 may be a potential biomarker for breast cancer and chronic kidney disease 10 , 19 . Also, Jianhong et al showed that circulating miR-21 is up-regulated at all clinical stages in gastric cancer patients, suggesting that circulating miR-21 level is up-regulated throughout cancer progression 20 .…”

Section: Introductionmentioning

confidence: 99%

Circulating miR-21, miR-29a, and miR-126 are associated with premature death risk due to cancer and cardiovascular disease: the JACC Study

Yamada

Suzuki

Fujii

et al. 2021

Sci Rep

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Primary prevention of premature death is a public health concern worldwide. Circulating microRNAs (miRNAs) have been described as potential diagnostic biomarkers for diseases as cancer and cardiovascular disease (CVD). This case-cohort study aimed to investigate the potential relationship between circulating miRNAs and the risk of premature death. A total of 39,242 subjects provided baseline serum samples in 1988–1990. Of these, 345 subjects who died of intrinsic disease (< 65 years old) and for which measurable samples were available were included in this study. We randomly selected a sub-cohort of 879 subjects. Circulatring miR-21, miR-29a, and miR-126 were determined using qRT-PCR. Conditional logistic regression models were used to analyse the data with respect to stratified miRNA levels. Multivariable logistic regression revealed that subjects with high circulating miR-21 and miR-29a individual levels had a significantly higher risk of total death, cancer death, and CVD death than those with medium miR-21 and miR-29a individual levels. Conversely, subjects with low circulating miR-126 levels had a significantly higher risk of total death than those with medium levels. This suggests that circulating miRNAs are associated with the risk of premature death from cancer and CVD, identifying them as potential biomarkers for early detection of high-risk individuals.

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Heated Tobacco Product Smokers in Japan Identified by a Population-Based Survey

Cited by 25 publications

References 10 publications

Prevalence and correlates of current use of heated tobacco products among a nationally representative sample of Korean adults: Results from a cross-sectional study

Prevalence and correlates of current use of heated tobacco products among a nationally representative sample of Korean adults: Results from a cross-sectional study

The Impact of Heated Tobacco Products on Smoking Cessation, Tobacco Use, and Tobacco Sales in South Korea

Circulating miR-21, miR-29a, and miR-126 are associated with premature death risk due to cancer and cardiovascular disease: the JACC Study

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