Heavy Metal Bioaccumulation as Indicators of Environmental Pollution and Health Risks

Matoka, Charles Mboya; Omolo, Samson Odira; Odalo, Josiah Ochieng

doi:10.9790/2402-08242431

Cited by 5 publications

(2 citation statements)

References 16 publications

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“…Metais pesados como chumbo, cádmio, mercúrio são sabidamente tóxicos aos organismos vivos [1][2][3]. Sua toxicidade se deve, em grande parte, à sua ligação não específica a proteínas, especialmente as cadeias laterais de resíduos como glutamato e aspartato que têm carboxilas carregadas negativamente, ou histidinas e cisteínas que têm grupos nucleofílicos imidazol e sulfidrila, respectivamente [4].…”

Section: Introductionunclassified

Aula Prática: Efeito de cádmio e pH na função de uma enzima: a luciferase de vagalume

Viviani,

Pelentir,

Bevilaqua

et al. 2023

Rev. Ens. Bioq.

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A desnaturação de proteínas pode ser causada por pHs extremos e metais pesados, como chumbo e mercúrio. Pequenas variações de pH ou baixas concentrações de metais pesados também afetam a estrutura e função de proteínas como enzimas, tendo efeitos tóxicos no metabolismo, entretanto, tais efeitos não são facilmente visualizados. A enzima luciferase, que catalisa a reação de oxidação da luciferina em vagalumes, produz luz verde-amarela em pH fisiológico. Em pH ácido ou na presença de certos metais pesados a cor da luz emitida muda para o laranja-avermelhado. Estas enzimas ao ligar os metais pesados ou prótons, mudam de conformação, afetando as interações eletrostáticas entre os aminoácidos do sítio-ativo e a molécula-produto (oxiluciferina), mudando a cor da luz emitida. Nesta aula prática a luciferase clonada do vagalume Amydetes vivianii, que é especialmente sensível ao cádmio, é utilizada para indicar variações de concentração deste metal e, também, para mudanças de pH, por meio da alteração da cor da luz do verde-amarelo-laranja. A bioluminescência produzida é, facilmente, visualizada em ambiente escuro, podendo ser fotografada com câmera de celular convencional.

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Section: Introductionunclassified

Aula Prática: Efeito de cádmio e pH na função de uma enzima: a luciferase de vagalume

Viviani,

Pelentir,

Bevilaqua

et al. 2023

Rev. Ens. Bioq.

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“…Due to their feeding habits and long life (30 years), Lethrinids can be used as an indicator of heavy metal bioaccumulation in the aquatic environment since they feed on mainly molluscs, crustaceans, sea urchins, hard-shell invertebrates and sometimes fishes (Carpenter and Allen, 1989). Increase in population together with increase in industrialization, have resulted in an increase in pollution to the marine environment and are causing potential risk for the marine organism and human health (Matoka et al ., 2014). Mauritius, being a small island is experiencing rapid growth in industry, tourism and population with consequent increase in production of more waste and the release of untreated sewage to the marine environment.…”

Section: Introductionmentioning

confidence: 99%

Heavy metal bioaccumulation in commercial Lethrinidae fish species in Mauritius

et al. 2017

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Concentrations of heavy metals arsenic, cadmium, lead and mercury and trace elements chromium, copper, nickel and zinc were tested in the muscle tissue of four commercial edible lethrinids fish species from different region of Mauritius. Sky emperor (Lethrinus mahsena) was collected from coastal regions as well as offshore regions (banks) for this study. Blackspot emperor (Lethrinus harak) and spangled emperor (Lethrinus nebulosus) were also studied for their popularity in the fish market. Condition factor was calculated for each fish and the highest value obtained was in Lethrinus mahsena collected from offshore regions (2.598 cm/g). Flame atomic absorption spectrometry was used to analyse copper, nickel and zinc while, graphite furnace technique was used for cadmium, chromium and lead. Mercury levels were evaluated with the cold vapour technique and arsenic with the thermal hydride cell. The level of lead, mercury, copper, nickel and zinc ranged from 0.0011-0.0024 mg/L, 0.0016-0.0036 mg/L, 0.080-0.389 mg/L, 0.566-1.192 mg/L and 0.219-0.422 respectively in wet weight. Interspecies variations in levels of heavy metals and trace elements were observed for nickel and no significant variations occurred for mercury, lead and zinc. Concentrations of heavy metals and trace elements were all within the permissible level except for nickel. As per this study, the Food Act 1998 of Mauritius must be reviewed in order to incorporate the Maximum Permissible Level for nickel.

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Theoretical studies of Zn2+ complexes with alkyl xanthate ligands: a thermochemical, electronic energy decomposition, and natural bond orbital analysis

Miranda¹,

Quintal²,

Ferreira³

2023

J Mol Model

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Heavy Metal Bioaccumulation as Indicators of Environmental Pollution and Health Risks

Cited by 5 publications

References 16 publications

Aula Prática: Efeito de cádmio e pH na função de uma enzima: a luciferase de vagalume

Aula Prática: Efeito de cádmio e pH na função de uma enzima: a luciferase de vagalume

Heavy metal bioaccumulation in commercial Lethrinidae fish species in Mauritius

Theoretical studies of Zn2+ complexes with alkyl xanthate ligands: a thermochemical, electronic energy decomposition, and natural bond orbital analysis

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