Heavy metal content (Hg2+, Cd2+, Pb2+) in various body parts: Its impact on cholinesterase activity and binding glycoproteins in the grasshopper Aiolopus thalassinus adults

Schmidt, Gerhard; Ibrahim, Nabil M

doi:10.1016/0147-6513(94)90016-7

Cited by 54 publications

(19 citation statements)

References 41 publications

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“…Olson and Christensen (1980) reported that strong and intermediate AChE inhibitions were found in fathead minnow (Pimephales promelas) treated (in vitro) with heavy metal cations and organometals, respectively. Schmidt and Ibrahim (1994) found that the ChE activity was increased to about 14% in adult grasshopper (Aiolopus thalassinus) treated (in vivo) with lead chloride. Suresh et al (1992) reported that the changes of ACh contents observed in the organs of mercury treated fish in different exposure periods were in the order 1 > 15 < 30 days.…”

Section: Cholinesterase Activity Assaymentioning

confidence: 99%

“…Both AChE and BuChE contribute to ChE activity in aquatic organisms (Sturm et al, 1999(Sturm et al, , 2000. Effects of mercury and its derivatives on ChE activity alteration have been widely reported in many previous works (Olson and Christensen, 1980;Suresh et al, 1992;Schmidt and Ibrahim, 1994;Devi and Fingerman, 1995). By binding of Hg to the sulfhydryl group, mercuric compounds can induce a conformational change in ChE.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Methylmercury accumulation, histopathology effects, and cholinesterase activity alterations in medaka (Oryzias latipes) following sublethal exposure to methylmercury chloride

Liao

Shi

et al. 2006

Environmental Toxicology and Pharmacology

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Section: Cholinesterase Activity Assaymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Methylmercury accumulation, histopathology effects, and cholinesterase activity alterations in medaka (Oryzias latipes) following sublethal exposure to methylmercury chloride

Liao

Shi

et al. 2006

Environmental Toxicology and Pharmacology

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“…Determination of Mercury: Mercury-Hydride-System (MHS-10) attached to a Perkin-Elmer 4000 AAS suitable for flameless cold-vapor technique (Devkota 1992;Schmidt et al 1992;Schmidt and Ibrahim 1994;Welz and Sperling 1997) was used for the determination of mercury. The finely ground samples were wet-digested in aqua regia at 140°C for 3 h. After cooling, the clear sample aliquots were diluted.…”

Section: Determination Of Metal Concentrations In Eggs and Freshly Hamentioning

confidence: 99%

Effects of Heavy Metals (Hg2+, Cd2+, Pb2+) During the Embryonic Development of Acridid Grasshoppers (Insecta, Caelifera)

Devkota

Schmidt

1999

Arch. Environ. Contam. Toxicol.

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Heavy metals present in the soil get differently accumulated in organisms and show different rates of toxicity at different stages of the life cycle of any organism living there. To see whether such toxicants get accumulated during the embryonic development and/or change the normal developmental processes of organisms exposed to heavy metals, freshly laid eggs and egg pods of two acridids, Aiolopus thalassinus and Eyprepocnemis plorans, were tested against different concentrations of Hg2+, Cd2+, and Pb2+. At increasing Hg2+ concentration in the substrate, an increased egg mortality and reduced nymphal hatching in A. thalassinus were observed, yet no change in the normal duration for embryonic development was noticed. A higher hatching rate of E. plorans nymphs than that of A. thalassinus could possibly be due to the higher tolerance, contributed by larger egg volume and thicker foam around the egg pods of the former. Treated concentrations of Hg2+ could be of sublethal (0.121 &mgr;g Hg2+/g substrate) to lethal (0.605 &mgr;g and more Hg2+/g substrate) doses. The mortality of eggs did not always increase with increasing substrate concentration of Cd2+ and Pb2+, and the hatching rates of both grasshopper species in many cases were even higher than that in the control. Still, lower accumulation factors of Cd2+ and Pb2+ than that of Hg2+ were found coupled with not increased mortality. The tested concentrations of Cd2+ and Pb2+ in the substrates, thus, could be of subacute doses. The embryonic development was found prolonged due to Cd2+ and Pb2+. During parallel egg and egg pod treatments, higher metal concentrations were found in not developed eggs than that in fresh nymphs hatching from the same substrates. This indicated the role of foam around the egg pods as "protective filter" against the toxic substances in the soil.

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“…In the last decade, several studies have shown that ChE activity could also be inhibited by metals, undetermined compounds of complex mixtures of pollutants, surfactants and detergents. [13][14][15][16] This perspective opened important possibilities concerning the use of cholinesterasic inhibition as a diagnostic tool in environmental assessment. However, the responsiveness of cholinesterasic activity following exposure to such contaminants is still a matter of debate, since not all metallic and detersive compounds exert this inhibitory effect.…”

Section: Introductionmentioning

confidence: 99%

Cholinesterase characterization inCorbicula flumineaand effects of relevant environmental contaminants: A pesticide (chlorfenvinphos) and a detergent (SDS)

Ramos¹,

Gonçalves²,

Antunes³

et al. 2012

Journal of Environmental Science and Health, Part B

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This study characterizes the cholinesterasic forms present in the bivalve Corbicula fluminea, through the analysis of differential affinity towards various substrates and inhibitors. This approach also permitted the validation of cholinesterase inhibition in the mentioned species for monitoring purposes by evaluating the inhibitory activity of a detergent (SDS) and a pesticide (chlorfenvinphos), both in vitro and in vivo. The cholinesterasic form present in the tissues of C. fluminea showed intermediate properties in terms of its relation with substrates and inhibitors. Furthermore, it was not inhibited by the detergent SDS under any of the test conditions, but was clearly inhibited by the selected organophosphate. The data show clearly that the main cholinesterasic form in C. fluminea is responsive to the organophosphate chlorfenvinphos, thus supporting the use of this biomarker for the environmental monitoring of specific contaminants such as anticholinesterasic pesticides. Despite not being commonly attained in the wild, the levels of chlorfenvinphos required to elicit a significant ChE inhibition were only one order of magnitude above actual values of aquatic contamination by this pesticide.

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Heavy metal content (Hg2+, Cd2+, Pb2+) in various body parts: Its impact on cholinesterase activity and binding glycoproteins in the grasshopper Aiolopus thalassinus adults

Cited by 54 publications

References 41 publications

Methylmercury accumulation, histopathology effects, and cholinesterase activity alterations in medaka (Oryzias latipes) following sublethal exposure to methylmercury chloride

Methylmercury accumulation, histopathology effects, and cholinesterase activity alterations in medaka (Oryzias latipes) following sublethal exposure to methylmercury chloride

Effects of Heavy Metals (Hg2+, Cd2+, Pb2+) During the Embryonic Development of Acridid Grasshoppers (Insecta, Caelifera)

Cholinesterase characterization inCorbicula flumineaand effects of relevant environmental contaminants: A pesticide (chlorfenvinphos) and a detergent (SDS)

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