Heavy metals in maternal and cord blood

Raghunath, R.; Tripathi, R. M.; Sastry, V.N.; Krishnamoorthy, T.M.

doi:10.1016/s0048-9697(00)00372-7

Cited by 49 publications

(28 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The cord BLLs found in other countries such as China, Mexico, India, Israel, Pakistan, Tanzania, Turkey, Spain, Belgium and indeed other countries were in general lower than the levels obtained in the present study [40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55].…”

Section: Discussioncontrasting

confidence: 84%

Towards Prenatal Biomonitoring in Eastern Nigeria: Assessing Lead Levels and Anthropometric Parameters of Newborns

Obi

Orisakwe

Okafor

et al. 2014

J UOEH

View full text Add to dashboard Cite

: The purpose of this study is to measure maternal blood lead level (BLL) and cord BLL in Nigeria and to compare Nigerian data with other data. We investigated the association among maternal and cord BLLs, and some anthropometric parameters of their babies. BLL was measured in the umbilical and maternal blood samples (using inductively coupled plasma / mass spectrometry (ICP-MS)) of 119 women who delivered at three different hospitals in Nnewi, South Eastern Nigeria. Anthropometric variables of the babies (head circumference, abdominal circumference, birth weight, birth length, crown rump length) were measured. Lead was detected at >10 μg/l in 10.9 percent of the maternal and 3.4 percent of the cord blood samples. The maternal BLL was 6.19 ± 2.77 (mean ± SD) μg/dl while cord BLL was 4.75 ± 2.59 (mean ± SD) μg/dl. With the exception of cord BLL and crown rump length positive correlation (R=0.204, P=0.026), neither the maternal nor the cord BLL showed any significant association with any of the childrenʼs anthropometric parameters.

show abstract

Section: Discussioncontrasting

confidence: 84%

Towards Prenatal Biomonitoring in Eastern Nigeria: Assessing Lead Levels and Anthropometric Parameters of Newborns

Obi

Orisakwe

Okafor

et al. 2014

J UOEH

View full text Add to dashboard Cite

show abstract

“…Lead can easily cross the placental barrier (Raghunath et al, 2000). The Flemish average concentration of 14.7 µg/L was in the range of median/mean levels of other European studies in the time period of the current study (Table 3).…”

Section: Cord Blood Pollutant Levelsmentioning

confidence: 55%

“…Embryonic development or physiological changes accompanying pregnancy, may impact mobilization from lipid reserves. Also Pb, accumulated in bone tissue over more than 20 years, may be mobilized during pregnancy and contribute to fetal exposure (Gulson et al, 1997;Lagerkvist et al, 1996;Raghunath et al, 2000). Cd accumulates in the human body, in particular in the kidney and liver and has an elimination half-life of 10-30 years (Jarup et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Organochlorine and heavy metals in newborns: Results from the Flemish Environment and Health Survey (FLEHS 2002–2006)

Koppen

Hond

Nelen

et al. 2009

Environment International

View full text Add to dashboard Cite

a b s t r a c t a r t i c l e i n f oTo collect regional information on internal levels of pollutants in humans in Flanders, 1196 mother-child pairs were systematically recruited in 2002-2003 via 25 maternities across Flanders. Cd, Pb, PCB congeners 118, 170, 138, 153 and 180, p,p′-DDE -a key metabolite of DDT-and hexachlorobenzene (HCB) were measured in cord blood or plasma. Cd was detected in 64% of the samples (geometric mean 0.21 µg/L cord blood). p,p′-DDE (110 ng/g plasma lipids) and Pb (14.7 µg/L blood), were measurable in nearly all samples. The individual PCB congeners could be detected in 40 to 81% of the newborns (138 + 153 + 180 = 64.4 ng/g plasma lipids). HCB (18.9 ng/g plasma lipids) and dioxin-like compounds measured by DR-CALUX® (23 pg CALUX-TEQ/g lipids) were above detection limit in more than 75% of the samples. Age and smoking habits of the mothers, did not influence the cord blood Pb and Cd levels. The organochlorines increased 4 to 9% per year of the mother's age (partial R 2 = 0.05 to 0.22). Mothers had 2.6% less PCBs in cord blood (partial R 2 = 0.02) for each unit increase in pre-pregnancy BMI. Season of delivery, breastfeeding previous children or consumption of local dairy products, were minor determinants. Up to 20% of the variability in organochlorine concentrations was explained by residence area. It was concluded that the place of birth in Flanders is an important determinant of the load of pollutants measured at the start of life. This underlines the validity of human biomonitoring on (relatively) small geographical scale.

show abstract

“…During the period of , Raghunath et al (2000 determined the concentration of zinc in maternal and cord blood for 148 mothers (20-25 years old) living Mumbai City, India. The mean concentrations of zinc were 6.335 and 2.527 mg/L in maternal and cord blood, respectively.…”

Section: General Population and Occupational Exposurementioning

confidence: 99%

Toxicological Profile for Zinc

2002

ATSDR's Toxicological Profiles

View full text Add to dashboard Cite

Heavy metals in maternal and cord blood

Cited by 49 publications

References 17 publications

Towards Prenatal Biomonitoring in Eastern Nigeria: Assessing Lead Levels and Anthropometric Parameters of Newborns

Towards Prenatal Biomonitoring in Eastern Nigeria: Assessing Lead Levels and Anthropometric Parameters of Newborns

Organochlorine and heavy metals in newborns: Results from the Flemish Environment and Health Survey (FLEHS 2002–2006)

Toxicological Profile for Zinc

Contact Info

Product

Resources

About