This dissertation concludes five years of doctoral study and research. I am deeply indebted to many exceptional scholars and inspiring individuals, who guide me through an voyage of discovery that never meant to be a downwind sailing.First and foremost, I would like to thank my advisor, Professor Ward Whitt, for the enlightening guidance throughout my life as a Ph.D. student. He is always a walking encyclopedia to me with his accurate pointers to the literature and his prompt and constructive feedback. His generosity in sharing his knowledge from both the mathematics and engineering point of view helped me greatly in understanding the big picture of the subject matter of this work. As a great educator and scholar, he has been and will always be a role model that I look up to.