We compute the genus zero bridge numbers and give lower bounds on the genus one bridge numbers for a large class of sufficiently generic hyperbolic twisted torus knots. As a result, the bridge spectra of these knots have two gaps which can be chosen to be arbitrarily large, providing the first known examples of hyperbolic knots exhibiting this property. In addition, we show that there are Berge and Dean knots with arbitrarily large genus one bridge numbers, and as a result, we give solutions to problems of Eudave-Muñoz concerning tunnel number one knots.