Height and body mass index distribution in children and adolescents with and without spina bifida

Bertapelli, Fábio; Baptista, Cyntia de Jesus Alves de Rogean; Mattiello-Sverzut, Ana Cláudia

doi:10.1016/j.jped.2023.07.002

Jornal de Pediatria

2024

DOI: 10.1016/j.jped.2023.07.002

|View full text |Cite

Height and body mass index distribution in children and adolescents with and without spina bifida

Fábio Bertapelli

Cyntia de Jesus Alves de Rogean Baptista

Ana Cláudia Mattiello-Sverzut

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Is body composition important in the context of renal function in pediatric neurogenic bladder?

Bagińska-Chyży,

Błahuszewska,

Korzeniecka-Kozerska

2024

Pediatr Nephrol

View full text Add to dashboard Cite

Background Neurogenic bladder due to myelomeningocele (MMC) is a significant risk factor for chronic kidney disease in children. Cystatin C (CysC) is a more accurate GFR marker than creatinine as it is unaffected by muscle mass but may be influenced by fat mass and BMI. This study evaluates: (1) GFR measurement accuracy using CysC and creatinine in MMC-related neurogenic bladder, (2) the relationship between body composition via bioelectrical impedance analysis (BIA) and renal parameters, and (3) the use of BIA for non-invasive GFR and body composition assessment. Methods Forty children (median age 9.96 years) underwent serum creatinine, CysC testing, and BIA measurements. We assessed age, sex, spinal lesion level, anthropometric measurements, BMI, and activity using Hoffer’s scale. GFR was calculated using five creatinine-based formulas, three CysC-based, and three combining CysC and creatinine, including BIA GFR as an alternative approach. Results Creatinine-based GFR estimates were significantly higher than CysC-based GFR. Although only 30% of MMC patients met the traditional BMI criteria for overweight/obesity, 62.5% were obese based on BIA-measured body fat percentage. Significant differences were found in CysC and CysC-based GFR equations within BMI and fat mass groups. Positive correlations were observed between CysC and body weight, BMI percentiles, body fat mass and fat-to-muscle ratio. Muscle mass positively correlated with creatinine. Conclusions BIA-determined fat mass percentage is a more sensitive obesity indicator than BMI in MMC patients. CysC levels and CysC-based GFR equations are influenced by body fat mass, requiring consideration of adiposity to avoid misestimating renal impairment. Graphical abstract

show abstract

Is body composition important in the context of renal function in pediatric neurogenic bladder?

Bagińska-Chyży,

Błahuszewska,

Korzeniecka-Kozerska

2024

Pediatr Nephrol

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Height and body mass index distribution in children and adolescents with and without spina bifida

Cited by 1 publication

References 15 publications

Is body composition important in the context of renal function in pediatric neurogenic bladder?

Is body composition important in the context of renal function in pediatric neurogenic bladder?

Contact Info

Product

Resources

About