Height and Heart Disease

Rosenbush, Stuart W.; Parker, Jeremy M.

doi:10.3909/ricm0678

Cited by 9 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, studies have shown that higher BMI, height, BSA, and neck circumference are associated with adverse CR and heart disease such as atrial fibrillation 30,35–37 . In our study, athletes with higher BMI, height, and neck circumference also had a higher likelihood of CR.…”

Section: Discussionsupporting

confidence: 62%

Assessment of Pulmonary Arteries Hemodynamics and Its Relationship With Cardiac Remodeling and Myocardial Fibrosis in Athletes With Four‐Dimensional Flow MRI

Tang,

Zhang,

Liu

et al. 2023

Magnetic Resonance Imaging

View full text Add to dashboard Cite

BackgroundExercise‐induced cardiac remodeling (CR) and myocardial fibrosis (MF) can increase cardiovascular risk in athletes. Early detection of pulmonary arterial hemodynamics parameters among athletes may be beneficial in optimizing the frequency of clinical follow‐ups.PurposeTo analyze the hemodynamics of pulmonary arteries and its relationship with CR and MF in athletes using four‐dimensional (4D) flow MRI.Study TypeProspective.PopulationOne hundred twenty‐one athletes (median age, 24 years; mean exercise per week 10 hours, for mean of 5 years) and twenty‐one sedentary healthy controls (median age, 25 years; exercise per week <3 hours, irregular pattern).Field Strength/SequenceTrue fast imaging with steady state free precession, time‐resolved 3D Cartesian phase‐contrast, and phase sensitive inversion recovery late gadolinium enhancement sequences at 3.0 T.AssessmentCR was defined as any cardiac parameters exceeding the 99th percentile upper reference limits, encompassing ventricular function, bi‐atrium and bi‐ventricle diameters, and ventricular wall thickness. MF was visually evaluated by three independent radiologists. 4D flow parameters were assessed in the main, right, and left pulmonary arteries (MPA, RPA, and LPA, respectively) and compared between different groups. Four machine learning (ML) models were developed to differentiate between athletes with and without CR and/or MF.Statistical TestsUnivariate analysis was used to compare groups. Area under the receiver operating characteristic curve (AUC) was used to assess the performance of the ML models.ResultsAthletes had significantly higher WSSmax in the MPA, RPA, and LPA than controls. Athletes with CR and/or MF (N = 30) had significantly lower RPmax from MPA to RPA than those without (N = 91). Among the ML models, the gradient boosting machine model had the highest performance, with an AUC of 0.90.ConclusionThe pulmonary arterial hemodynamics parameters could differentiate CR and/or MF in athletes, which may be potential to assist in optimizing frequency of follow‐up.Evidence Level1Technical EfficacyStage 2

show abstract

Section: Discussionsupporting

confidence: 62%

Assessment of Pulmonary Arteries Hemodynamics and Its Relationship With Cardiac Remodeling and Myocardial Fibrosis in Athletes With Four‐Dimensional Flow MRI

Tang,

Zhang,

Liu

et al. 2023

Magnetic Resonance Imaging

View full text Add to dashboard Cite

show abstract

“…Although atherosclerosis is a multifactorial process, inflammatory and immunological factors are considered to play critical roles. [1][2][3] Recently, there have been many studies investigating the role of inflammatory and biochemical markers derived from complete blood count (CBC) in CAD. [4][5][6][7] Although an abundance of studies report strong relationships between neutrophil/ lymphocyte (N/L) ratio, platelet/lymphocyte (P/L) ratio, platelet distribution width (PDW) values, red blood cell distribution width (RDW) values, and anatomical CAD, there are few studies evaluating the relationship between N/L ratio, P/L ratio, PDW values, RDW values, and myocardial perfusion.…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between Some Complete Blood Count Parameters and Myocardial Perfusion: A Scintigraphic Approach

et al. 2015

View full text Add to dashboard Cite

Recent studies have shown that there is a relationship between some inflammatory and biochemical markers derived from complete blood count (CBC) such as neutrophil/lymphocyte (N/L) ratio, platelet/lymphocyte (P/L) ratio, platelet distribution width (PDW), red blood cell distribution width (RDW), and coronary artery disease (CAD). The aim of this study was to determine N/L ratio, P/L ratio, PDW values, and RDW values, which are associated with myocardial perfusion in patients diagnosed with CAD. This study included 262 patients (149 with myocardial ischemia/infarction and 113 with normal myocardial perfusion) undergoing myocardial perfusion scintigraphy (MPS) with CBC within 90 days of MPS. Myocardial perfusion parameters such as summed stress score and summed difference score (SDS) were compared with N/L ratio, P/L ratio, PDW values, and RDW values. Neutrophil counts and N/L ratios were significantly higher in patients diagnosed with myocardial ischemia and/or infarct. However, there was no statistically significant relationship between myocardial perfusion abnormalities and P/L ratio, PDW values, and RDW values. This study showed that N/L ratio is related to myocardial ischemia/infarction and correlated to left ventricular ejection fraction (LVEF).

show abstract

“…studied that 24-h ambulatory mean arterial pressure significantly increased in taller males [ 50 ]. Furthermore, it is recently reported that body height is closely related with the risk of cardiovascular diseases [ 51 ], atrial fibrillation and mitral valve prolapse [ 52 ]. These studies suggested that height might be an unexplored contributing factor to metabolic abnormalities which guide the search for much-needed effective therapies in this population.…”

Section: Discussionmentioning

confidence: 99%

Predictive modeling the probability of suffering from metabolic syndrome using machine learning: A population-based study

Hu¹,

Li²,

Wen³

et al. 2022

Heliyon

View full text Add to dashboard Cite

Height and Heart Disease

Cited by 9 publications

References 0 publications

Assessment of Pulmonary Arteries Hemodynamics and Its Relationship With Cardiac Remodeling and Myocardial Fibrosis in Athletes With Four‐Dimensional Flow MRI

Assessment of Pulmonary Arteries Hemodynamics and Its Relationship With Cardiac Remodeling and Myocardial Fibrosis in Athletes With Four‐Dimensional Flow MRI

The Relationship Between Some Complete Blood Count Parameters and Myocardial Perfusion: A Scintigraphic Approach

Predictive modeling the probability of suffering from metabolic syndrome using machine learning: A population-based study

Contact Info

Product

Resources

About