Helical CT-enteroclysis in the detection of small-bowel tumours: a meta-analysis

Soyer, Philippe; Aout, Mounir; Hoeffel, Christine; Vicaut, Éric; Placé, Vinciane; Boudiaf, Mourad

doi:10.1007/s00330-012-2595-y

Cited by 53 publications

(25 citation statements)

References 39 publications

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“…For sporadic lesions, small bowel follow-through has a sensitivity of approximately 50%, which is equivalent to CT performed without small bowel distension (Soyer et al, 2011;Maglinte, 2006Maglinte, , 2005. By contrast, CT-enteroclysis has a sensitivity of 85-95% and a specificity of 90-96% (Boudiaf et al, 2004;Pilleul et al, 2006;Soyer et al, 2013a). Similarly, MR-enteroclysis has a sensitivity of 86-91%, a specificity of 95-98%, and an accuracy of 97% (Masselli et al, 2009;Van Weyenberg et al, 2010).…”

Section: Imaging Findingsmentioning

confidence: 88%

Gastrointestinal cancers in inflammatory bowel disease: An update with emphasis on imaging findings

Barral

Dohan

Allez

et al. 2016

Critical Reviews in Oncology/Hematology

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Section: Imaging Findingsmentioning

confidence: 88%

Gastrointestinal cancers in inflammatory bowel disease: An update with emphasis on imaging findings

Barral

Dohan

Allez

et al. 2016

Critical Reviews in Oncology/Hematology

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“…The combination of small bowel distension with negative contrast and mural enhancement with intravenous contrast allows detailed assessment of the small bowel wall 5. A recent meta-analysis (n=696) reported that CT enteroclysis had a per-patient pooled sensitivity of 92.8% for SBTs 6. There is, however, a relative paucity of studies looking at CTE detection of SBTs.…”

Section: Discussionmentioning

confidence: 99%

A jejunal GIST presenting with obscure gastrointestinal bleeding and small bowel obstruction secondary to intussusception

Sadeghi

Lanzon-Miller

2015

BMJ Case Reports

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SUMMARYA 68-year-old man with episodes of overt obscure gastrointestinal (GI) bleeding was investigated with multiple upper and lower GI endoscopies, CT enterography and capsule endoscopy, but no cause was found. He then presented acutely with small bowel obstruction. A laparotomy revealed complete small bowel obstruction secondary to jejunal intussusception over a 4 cm intraluminal polyp. Following resection and primary anastomosis, histology revealed that the polyp was a GI stromal tumour (GIST). This is an exceptionally uncommon presentation of a rare tumour. It is surprising that this tumour was not detected by CT enterography and not seen on capsule endoscopy. Immunohistochemistry and mutation analysis of the GIST suggested that it had a low risk of metastatic disease, but a high risk of recurrence. Staging CT scans did not reveal evidence of distal spread. The patient is currently receiving 3 years of chemotherapy with imatinib.

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“…The diagnostics of small intestine diseases may include computed tomography (CT) enterography/enteroclysis or magnetic resonance imaging (MRI) enterography/ /enteroclysis, which locate the primary focus in the small intestine in approximately 90-97% of patients [41][42][43]. For the follow-up concerning small intestine diseases, CT or MRI enterography should be applied.…”

Section: Primary Tumour Locationmentioning

confidence: 99%

Nowotwory neuroendokrynne jelita cienkiego i wyrostka robaczkowego — zasady postępowania (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

Bednarczuk¹,

Bolanowski²,

Zemczak³

et al. 2017

Endokrynologia Polska

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 224Neuroendocrine neoplasms of the small intestine and appendix -management guidelines Bednarczuk Tomasz et al. SZKOLENIE PODYPLOMOWE AbstractThis study presents the revised Polish guidelines regarding the management of patients suffering from neuroendocrine neoplasms (NENs) of the small intestine and appendix. The small intestine, especially the ileum, is the most common location for these neoplasms. Most are well differentiated and slow growing. Their symptoms may be atypical, which can result in delayed or accidental diagnosis. Appendicitis is usually the first manifestation of NEN in this location. Typical symptoms of carcinoid syndrome occur in approximately 20-30% of patients suffering from small intestinal NENs with distant metastases. The main cause of death in patients with carcinoid syndrome is carcinoid heart disease.The most useful laboratory test is the determination of chromogranin A, while concentration of 5-hydroxyindoleacetic acid is helpful in the diagnostics of carcinoid syndrome. For visualisation, ultrasound, computed tomography, magnetic resonance imaging, colonoscopy, video capsule endoscopy, double-balloon enteroscopy, and somatostatin receptor scintigraphy may be used. A detailed histological report is crucial for the proper diagnostics and therapy of NENs of the small intestine and appendix. The treatment of choice is surgical management, either radical or palliative. The pharmacological treatment of the hormonally active and non-active small intestinal NENs as well as NENs of the appendix is based on long-acting somatostatin analogues. In patients with generalised NENs of the small intestine in progress during the SSA treatment, with good expression of somatostatin receptors, the first-line treatment should be radioisotope therapy, while targeted therapies, such as everolimus, should be considered afterwards. When the above therapies are exhausted, in certain cases chemotherapy may be considered.(Endokrynol Pol 2017; 68 (2): 223-236)

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Helical CT-enteroclysis in the detection of small-bowel tumours: a meta-analysis

Abstract: Our meta-analysis confirms that helical CT-enteroclysis has high degrees of sensitivity and specificity for small-bowel tumour detection. However, our findings reinforce the need for more standardised individual studies.

Cited by 53 publications

References 39 publications

Gastrointestinal cancers in inflammatory bowel disease: An update with emphasis on imaging findings

Gastrointestinal cancers in inflammatory bowel disease: An update with emphasis on imaging findings

A jejunal GIST presenting with obscure gastrointestinal bleeding and small bowel obstruction secondary to intussusception

Nowotwory neuroendokrynne jelita cienkiego i wyrostka robaczkowego — zasady postępowania (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

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