Helicobacter pylori Prevalence by Urea Breath Test in a Southwestern Nigerian Population

Abstract

The study population consisted of male and female dyspeptics aged 18 and above referred to the unit for urea breath test from February 2015 to December 2018. Patients' demographic information and H. pylori status were extracted from the test logbook and analyzed with IBM-SPSS Statistics for Windows, Version 22.0. Armonk, NY: IBM Corp. RESULTS: A total of 203 patients who had pre-eradication test within the period considered were included. The mean age was 44.6 (±16.4) while the age range was 18-83 years. Eighty-two (40.4%) were males while 121 (59.6%) were females. A total of 106 (52.2%) tested positive for H. pylori among all the subjects. There was no significant age-related difference in the prevalence (p = 0.333). The female gender was observed to have a higher prevalence (56.2%) than the male gender (46.3%) but the difference was not statistically significant (p = 0.198). CONCLUSION: The prevalence rate of H. pylori infection in Nigeria is high but it varies widely from one study to another depending on the diagnostic method used. A nationwide populationbased study utilizing a user-friendly and reliable diagnostic method like the urea breath test is highly desirable.