Heligmosomoides polygyrus or Nematospiroides dubius?

Assessment of the Anthelmintic Efficacy of an Aqueous Crude Extract ofVernonia amygdalina.

“…This is lethal to blood-sucking helminths (Behinke et al, 1991). Because it has been shown that lactones, vernodalin, and vernolide, inhibited both the movement and egglaying capacity of schistosomes, it may well be that these compounds have uncoupling effects on the mitochondria reaction involved in electron transport-associated event to form ATP generation.…”

Type 2 Innate Immunity in Helminth Infection Is Induced Redundantly and Acts Autonomously following CD11c+Cell Depletion

“…Wild-type BALB/c and C57BL/6 mice and CD11c.DOG mice on the C57BL/6 background, which express human diphtheria toxin receptor and ovalbumin amino acids (aa) 140 to 386 under the control of the CD11c promoter (19,20), were bred and maintained in a specific-pathogen-free facility at the University of Edinburgh. Mice were injected subcutaneously (s.c.) with 250 N. brasiliensis infective third-stage larvae (L3) or with 200 H. polygyrus bakeri (7,30) L3 using a gavage tube, or with 50 g NES into the hind foot, and lymph node (LN) cells were recovered 5 to 7 days later. Excretory-secretory antigens from adult H. polygyrus (HES) and N. brasiliensis (NES) were prepared as previously described (18,21).…”

Molecular evidence that Heligmosomoides polygyrus from laboratory mice and wood mice are separate species

“…The worm from Peromyscus was virtually identical to an Old World nematode, Heligmosomoides polygyrus, a dominant helminth in the Eurasian field or wood mouse Apodemus sylvaticus (see Behnke et al 1991 for a review of the early taxonomic history of this worm). The life-history traits and ecology of this Operational Taxonomic Unit (OTU) have been explored extensively (Gregory et al 1992 ;Quinnell, 1992 ;Abu-Madi et al 1998, 2000Behnke et al 1999).…”