2016
DOI: 10.1016/j.dental.2016.02.003
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HEMA release and degree of conversion from a resin-modified glass ionomer cement after various delays of light activation

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Cited by 20 publications
(29 citation statements)
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“…These observations were related to the cement chemical compositions, in which ZP cements contain phosphoric acid, ZOE cements contain eugenol, and R cements are acrylate‐based, with these components being known skin irritants . Furthermore, studies have shown that R and RMGIC cements leach unreacted hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) monomers and fluoride ions over a period of several weeks, which can lead to pulpal inflammation and cytotoxicity in preosteoblast and fibroblast cells . High concentrations of eugenol have long been associated with adverse inflammatory reaction, hypersensitivity, and cytotoxicity when in contact with soft‐tissue‐forming and osteoblastic cells .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…These observations were related to the cement chemical compositions, in which ZP cements contain phosphoric acid, ZOE cements contain eugenol, and R cements are acrylate‐based, with these components being known skin irritants . Furthermore, studies have shown that R and RMGIC cements leach unreacted hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) monomers and fluoride ions over a period of several weeks, which can lead to pulpal inflammation and cytotoxicity in preosteoblast and fibroblast cells . High concentrations of eugenol have long been associated with adverse inflammatory reaction, hypersensitivity, and cytotoxicity when in contact with soft‐tissue‐forming and osteoblastic cells .…”
Section: Discussionmentioning
confidence: 99%
“…38 Furthermore, studies have shown that R and RMGIC cements leach unreacted hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) monomers and fluoride ions over a period of several weeks, which can lead to pulpal inflammation and cytotoxicity in preosteoblast and fibroblast cells. [39][40][41][42][43][44] High concentrations of eugenol have long been associated with adverse inflammatory reaction, hypersensitivity, and cytotoxicity when in contact with soft-tissue-forming and osteoblastic cells. 45,46 The observations of increased cytotoxicity for R, RMGIC, and ZOE cement compositions in this study can be related to these previous observations in the literature.…”
Section: Discussionmentioning
confidence: 99%
“…Commercial materials and their compositions used in the study are provided in Table 1 8,[18][19][20] . Materials that require mixing were prepared according to their manufacturer instructions.…”
Section: Methodsmentioning
confidence: 99%
“…Resin-modified glass ionomer cements (RMGICs) has been developed to enable the command setting by photo-polymerization in addition to acid-base neutralization reaction 7) . However, it has been demonstrated that the polymerization of methacrylate monomers may be affected by the restricted radicals mobility from cement hardening through acid-base reaction 8) . This may reduce early strength and increase the risk of toxic monomer release from RMGICs 9) .…”
Section: Introductionmentioning
confidence: 99%
“…This finding could be related to the incomplete curing reaction of this resin-modified glass ionomer cement during the manufacturer's claimed chemical-curing period of 2.5 min. It was previously shown that chemical-curing without the additional light-curing of a resin-modified glass ionomer resulted in a significantly lower degree of conversion compared to that achieved by light-curing [27]. Exposure of the chemically-cured Vitrebond nonLC to light during the subsequent adhesive curing could facilitate additional polymerization of the uncured methacrylate groups in this material.…”
Section: Discussionmentioning
confidence: 97%