Hemangioma esclerosante pulmonar como nódulo pulmonar solitario: comunicación de un caso

Abstract

Lung sclerosing hemangioma is an uncommon tumor that presents as a solitary asymptomatic nodule and that affects middle age women. It derives from type II pneumocytes. We report a 52 years old female with a solitary lung nodule detected in a chest X ray requested for the diagnosis of an acute respiratory disease. The nodule was excised by video thoracoscopy and the frozen section biopsy was informed as a non small cell undifferentiated carcinoma. Therefore an inferior right lobectomy with lymph node resection was performed. The definitive biopsy was informed as a lung sclerosing hemangioma.

Pulmonary sclerosing pneumocytoma mimicking lung cancer: Case report and review of the literature

“…Patients are usually women with a mean age of 46 years. The most common presenting form is an asymptomatic solitary pulmonary nodule that can grow up to 7 cm in diameter, although 73% of lesions are smaller than 3 cm 2, 5. PSP typically presents on chest radiograph as a peripheral, solitary, well‐defined, homogenous nodule or mass without predilection for a particular lobe.…”

Expression of ALDH and SOX-2 in Pulmonary Sclerosing Pnemocytoma (PSP) of the Lung: Is There a Meaning Behind?

“…Recurrence for this disease is infrequent, although not impossible to find. The nomenclature for this benign disease ( 8 – 10 ) has recently been renamed “pulmonary sclerosing pneumocytoma” ( 6 ).…”

“…PSP is difficult to recognize due to the lack of significant clinical or imaging features and at first glance appears to be a benign nodule such as hamartoma, tuberculoma, bronchial cysts, or certain lung cancer nodules ( 5 ). Although the etiology and pathogenesis of PSP are still unclear, recently it has been clarified that PSP is derived from the epithelial part of the lung, which gives rise to the name sclerosing pneumocytoma of the lung ( 6 ). PSPs are composed of four major histologic patterns, which are hemangiomatous, papillary, sclerotic, and solid, as well as different radiological characteristics made apparent by computed tomography (CT) findings according to their composition ( 6 – 14 ).…”

“…Although the etiology and pathogenesis of PSP are still unclear, recently it has been clarified that PSP is derived from the epithelial part of the lung, which gives rise to the name sclerosing pneumocytoma of the lung ( 6 ). PSPs are composed of four major histologic patterns, which are hemangiomatous, papillary, sclerotic, and solid, as well as different radiological characteristics made apparent by computed tomography (CT) findings according to their composition ( 6 – 14 ). It has been described that PSP typically presents as a well-defined, juxta-pleural nodule with strong and homogeneous enhancement ( 14 – 16 ) on CT, while several studies have analyzed CT findings of PSP and its pathologic correlation ( 14 , 15 ).…”

“…Patients are usually asymptomatic in which the PSP is detected coincidentally. Moreover, a cough, chest pain, and haemoptysis may also occur ( 6 ). PSP is often a solitary, well-defined, round or oval, homogeneous nodule, or mass ( 14 – 16 ); however, there are also cases of metastases to the lymph nodes, pleura, and bones ( 14 , 17 , 18 ).…”