Hemangioma of spleen with spontaneous, extra‐peritoneal rupture, with associated splenic tuberculosis — an unusual presentation

Rao, Ravi Mohan; Ghose, Rita; Sawhney, Sukhpal; Berry, Manorama

doi:10.1111/j.1440-1673.1993.tb00025.x

Cited by 13 publications

(7 citation statements)

References 6 publications

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“…In 711 patients (84·1 per cent) a single aetiological factor was found. In 69 patients (8·2 per cent) the splenic rupture was related to two underlying pathologies (for example, splenic tuberculosis and cavernous haemangioma of the spleen13), and in six (0·7 per cent) the splenic rupture was caused by a combination of three aetiological factors (for example, haemophagocytic syndrome, splenic tuberculosis and sarcoidosis of the spleen14). The coincidence of several aetiological factors in a single patient resulted in a total of 926 aetiological factors for ASR in the 845 patients.…”

Section: Resultsmentioning

confidence: 99%

Systematic review of atraumatic splenic rupture

Renzulli

Hostettler

Schoepfer

et al. 2009

British Journal of Surgery

318

394

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Section: Resultsmentioning

confidence: 99%

Systematic review of atraumatic splenic rupture

Renzulli

Hostettler

Schoepfer

et al. 2009

British Journal of Surgery

318

394

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“…These patients had HIV infection3,4,7, longstanding sarcoidosis5, or chronic renal disease requiring hemodialysis6. Thus far, 3 cases have been reported in immunocompetent patients8-10. Splenic hemangioma was a factor in one of these cases8.…”

Section: Discussionmentioning

confidence: 99%

“…Thus far, 3 cases have been reported in immunocompetent patients8-10. Splenic hemangioma was a factor in one of these cases8.…”

Section: Discussionmentioning

confidence: 99%

“…Most spontaneous ruptures in splenic TB were reported as initial manifestations, occurring before initiation of antituberculous chemotherapy3-5,8,9. This suggests that the diagnosis of splenic TB is often delayed due to the lack of specific symptoms and signs.…”

Section: Discussionmentioning

confidence: 99%

“…Very few studies have reported spontaneous splenic rupture in splenic TB3-10. The majority of these cases occurred in immunocompromised patients3-7 or before administration of antituberculous chemotherapy3-5,8,9. Spontaneous rupture as a paradoxical reaction during successful chemotherapy has not been reported in an immunocompetent patient.…”

Section: Introductionmentioning

confidence: 99%

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Spontaneous Splenic Rupture as a Paradoxical Reaction during Treatment for Splenic Tuberculosis

et al. 2013

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This report describes a rare case of a patient with splenic tuberculosis (TB) who developed spontaneous splenic rupture after 10 weeks of antituberculous chemotherapy. The patient responded well to the antituberculous regimen prior to the spontaneous splenic rupture. We considered a paradoxical reaction as a cause of the splenic rupture. The patient underwent splenectomy and continuously received initial antituberculous drugs without change. To the best of our knowledge, this is the first report of spontaneous splenic rupture as a paradoxical reaction to antituberculous chemotherapy in an immunocompetent host with splenic TB.

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Spontaneous splenic rupture: Report of five cases and a review of the literature

Tran

Larsen

1997

Emergency Radiology

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Spontaneous splenic rupture without an antecedent history of trauma is an unusual entity. There have been sporadic case reports of spontaneous splenic rupture since its original 19th-century description. Since 1986, five cases of spontaneous splenic rupture have been treated at our institution. Two patients developed ruptures in apparently normal spleens. In the remaining three patients, splenic rupture was associated with infectious mononucleosis, a benign mesothelial cyst, and a dermoid cyst. Radiographic findings, etiologies, and the pertinent literature are reviewed. SPlenic rupture is a well-described entity which is typically associated with trauma and can be found in up to 30% of patients undergoing surgery for blunt abdominal trauma (1). Spontaneous (or pathologic) rupture of the spleen, however, is a relatively uncommon entity. Since 1Kokitansky's description of splenic rupture involving a leukemic patient in 1861 (2), as well as King's report of splenic rupture in a patient with infectious mononucleosis in 1941 (3), spontaneous splenic rupture has become much more widely recoguized. It has been associated with a wide variety of neoplastic, hematologic, autoimmune, and infectious diseases as well as several benign conditions. Spontaneous splenic rupture also has occasionally been reported in normal spleens (4). Since 1986, we have documented five cases of spontaneous splenic rupture. Upon pathologic examination, three of these patients had benign mesothelial cyst, dermoid cyst, and infectious mononucleosis. Two patients had apparently normal spleens. We present these five cases, as well as a review of the literature. CASE 1The patient was a 62-year-old man who presented with acute onset of lower left quadrant and epigastric pain after a meal. The patient had a past medical history significant for several previous myocardial infarctions, repair of an abdominal aortic aneurysm, and chronic renal failure. The pain was described as sharp and radiating to the left shoulder. Systolic blood pressure in the emergency department was 60 mmHg. Physical examination revealed a mildly distended abdomen with marked epigastric tenderness. Hematocrit was low at 28%. A computed tomographic (CT) scan of the abdomen revealed a splenic laceration with hemoperitoneum (Fig. 1). The patient subsequently underwent a splenectomy. Pathology demonstrated a normal-sized spleen which had an irregularly torn capsule as well as an intraparenchymal hematoma. The remainder of the splenic parenchyma was normal. CASE 2The patient was a 51-year-old woman with a remote history of ovarian carcinoma who presented after 24 hours ofepigastric and left upper quadrant pain radiating to the left shoulder. Vital signs and hematocrit on admission were normal. An abdominal CT scan, however, demonstrated splenic rupture with intraperitoneal hemorrhage. The patient was urgently brought to the operating room, where a total splenectomy was performed. Gross pathology demonstrated a torn splenic capsule as well as a subcapsular hematoma. The spleen Emergen...

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Hemangioma of spleen with spontaneous, extra‐peritoneal rupture, with associated splenic tuberculosis — an unusual presentation

Cited by 13 publications

References 6 publications

Systematic review of atraumatic splenic rupture

Systematic review of atraumatic splenic rupture

Spontaneous Splenic Rupture as a Paradoxical Reaction during Treatment for Splenic Tuberculosis

Spontaneous splenic rupture: Report of five cases and a review of the literature

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