Hemangiomas and Spitz Nevi

Ah, Hartley; Je, Rasmussen

doi:10.1542/pir.11-9-262

Cited by 5 publications

(2 citation statements)

References 0 publications

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“…Spitz nevus, in contrast, is an acquired melanocytic lesion that mainly occurs in children. 4 About 1 to 2 percent of all excised melanocytic lesions in children are Spitz nevi. 5,6 This should make Spitz nevus and hemangioma (any type) topographically coincidental at least occasionally.…”

Section: Introductionmentioning

confidence: 99%

Spitz Nevus Intermingling With a Hemangioma

Fernández-Flores

Saeb‐Lima

2016

The American Journal of Dermatopathology

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We report on a Spitz nevus intermingling with a hemangioma in the same biopsy from the right thigh of a 10-year-old boy. The hemangioma was made of dilated vessels in superficial areas but of narrow and angulated vessels in the deep and lateral zones. The Spitz nevus was typical, showing maturation, and no worrisome cytological features. The immunohistochemical study demonstrated expression by the vascular component of CD31, CD34, factor VIII-related antigen, and Wilms tumor 1, whereas the vessels did not express D2-40 human herpes virus 8 or glucose transporter-1. The melanocytic component expressed HMB-45 (weakly and mainly in the superficial zones), Melan-A and S-100 protein. A perivascular continuous layer of pericytes expressing smooth muscle actin was also evident.

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Section: Introductionmentioning

confidence: 99%

Spitz Nevus Intermingling With a Hemangioma

Fernández-Flores

Saeb‐Lima

2016

The American Journal of Dermatopathology

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“…In 70–90% of the cases, the lesion is single and the diameters of the hemangiomas on skin may vary from several millimeters to huge dimensions exceeding 20 cm. Approximately 10% of cases with hemangiomas develop complications, especially cases with diffuse hemangiomatosis are in greater risk for complications and unpleasant prognosis 3,6–8.…”

Section: Introductionmentioning

confidence: 99%