Hémangiomatose multifocale bronchique, ganglionnaire, splénique et osseuse

Ancel, Julien; Pérotin, J.M.; Dewolf, Maxime; Launois, Claire; Hagenburg, Jean; Lebargy, F.

doi:10.1016/j.rmr.2019.12.003

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…However, some lesions may not be well enhanced due to the absence of large supplying arteries or the presence of significant arteriovenous shunt ( 8 ). In this case, PET/CT might offer significant assistance in diagnosing PCHs, in general, which do not show abnormally high uptake of 18 F-FDG and 11C-choline (two common oncologic radiotracers), enabling distinction from malignant tumours and certain pulmonary inflammatory lesions that exhibiting increased uptake ( 9 ). Bronchoscopy may identify haemangiomas that project into the bronchial lumen.…”

Section: Discussionmentioning

confidence: 99%

“…The hilar and mediastinal lymph nodes were not enlarged (Figure 1). Laboratory examination as following: Whole blood leukocytes, 6.03x10 9 /L [neutrophils, 64.4% (normal range, 50-70%); lymphocytes, 28.2% (normal range, 20-50%); monocytes, 5% (normal range, 3-10%); eosinophils, 1.7% (normal range, 0.4 -8%); basophils, 0.7% (normal range, 0-1%)]; red blood cells, 3.78x10 12 /L (normal range, 4.3 to 5.8x10 12 /L); hemoglobin, 120 g/L (normal range, 115-150 g/L); platelets, 243x10 9 /L (normal range, 125-350x10 9 /L); blood glucose, 4.67 mmol/L (normal range, 3.9-6.1 mmol/L); total bilirubin, 10.31 µmol/L (normal range, 3.42-20.5 µmol/L); aspartate aminotransferase, 17.3 U/L (normal range, 0-40 U/L); alanine aminotransferase, 11.4 U/L(normal range, 0-50 U/L); lactate dehydrogenase, 102 IU/L (normal range, 100-240 IU/L); highly sensitive C reactive protein, 1.52 mg/L (normal range, 0-5 mg/L); and Erythrocyte Sedimentation Rate, 5 mm/h (normal range, 0-20 mm/h). A urinalysis and microscopic examination were normal.…”

Section: Case Reportmentioning

confidence: 99%

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Multiple pulmonary cavernous haemangiomas with concurrent primary pulmonary adenocarcinoma: a case report and literature review

Wang,

Ren,

You

et al. 2024

Front. Oncol.

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BackgroundCavernous haemangiomas (CHs) commonly occurred in the skin, subcutaneous tissue, muscles, and liver. Pulmonary cavernous haemangiomas (PCHs) are quite rare and usually present with nonspecific clinical symptoms. When lung cancer patients are complicated with pulmonary cavernous haemangiomas, radiologically, these haemangioma lesions can be easily misinterpreted as intrapulmonary metastases, potentially resulting in misdiagnosis, or missed diagnosis.Case presentationThe present study reported the case of a 53−year−old female patient with pulmonary adenocarcinoma coexisting with multiple PCHs. 18F−FDG-Positron emission tomography-computed tomography (PET-CT) showed an elevated glucose metabolism in the apicoposterior segment of the left upper lobe; however, the other nodules were not hypermetabolic. Percutaneous lung biopsy was performed on the nodule in the apicoposterior segment of the left upper lobe, which were diagnosed as primary adenocarcinoma. Some nodules in the upper left lobe underwent wedge resection by video-assisted thoracic surgery (VATS) and intraoperative frozen section identified as PCHs. Finally, the patient underwent lobectomy of the left upper lobe via VATS, cancerous nodule in the apicoposterior segment of the left upper lobe underwent genetic molecular testing of PCR−Sanger sequencing, suggested EGFR mutation, and patient received treatment with Osimertinib. During the 4−months follow−up, contrast−enhanced CT showed no recurrence of either disease. PCHs are rare benign tumours of the lung, which can lead to misdiagnosis due to their non-specific clinical symptoms and radiological features, especially when they coexist with lung cancer. PCHs is easily misunderstood as metastatic lung cancer, in this case, PET-CT can assist in differentiating benign from malignant. For the cases of early lung cancer complicated with PCHs, lung cancer can be surgically resected, and whether PCHs should be removed or not should be determined according to the size and distribution of the lesions.

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Section: Discussionmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

Multiple pulmonary cavernous haemangiomas with concurrent primary pulmonary adenocarcinoma: a case report and literature review

Wang,

Ren,

You

et al. 2024

Front. Oncol.

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Pulmonary cavernous hemangioma combined with smooth muscle hyperplasia: a case report and review of the literature

Igarashi

Kosaka

Sugano

et al. 2023

Gen Thorac Cardiovasc Surg Cases

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Background Cavernous hemangiomas are usually located in the liver, skin, and subcutaneous tissues. Although they can arise from any organ, cavernous hemangiomas rarely occur as a pulmonary tumor. We herein report a rare case of a pulmonary cavernous hemangioma that was surgically resected. Case presentation A woman in her 40s was found to have 2 well-defined nodules in the lower lobe of the left lung by computed tomography during following up of bladder cancer. She had a history of surgery for tetralogy of Fallot at 6 years old and pulmonary valve replacement for pulmonary valve insufficiency in her late 30s. She had also undergone surgery for bladder cancer. Although there was no accumulation of 18F-fluorodeoxyglucose on positron emission tomography (PET), the tumor slowly grows. Surgical resection was therefore performed to obtain a definitive diagnosis. The postoperative histological examination revealed an encapsulated nodule comprising large, dilated vessels lined with vascular endothelium and filled with blood, which led to the diagnosis of a pulmonary cavernous hemangioma. Conclusion We experienced a rare case of pulmonary cavernous hemangioma and reviewed the previous reports.

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Hémangiomatose multifocale bronchique, ganglionnaire, splénique et osseuse

Cited by 2 publications

References 9 publications

Multiple pulmonary cavernous haemangiomas with concurrent primary pulmonary adenocarcinoma: a case report and literature review

Multiple pulmonary cavernous haemangiomas with concurrent primary pulmonary adenocarcinoma: a case report and literature review

Pulmonary cavernous hemangioma combined with smooth muscle hyperplasia: a case report and review of the literature

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