Hemangiomatous Penile Horn

Penile cancer

“…221 Predisposing factors also include poor hygiene, trauma, and viral infections (HPV 16). [222][223][224][225] It clinically appears as a single or, less often, multiple 222,223 hard and conical keratotic outgrowth of variable size, yellowish or whitish in color, with a bulging erythematous base (Fig 3). 223,226 Histologically, changes typical of different underlying conditions, including benign epidermal J AM ACAD DERMATOL hyperplasia, warts, keratoacanthoma, hemangioma, and in situ or invasive carcinomas (SCC or verrucous carcinoma), may be observed.…”

“…223,226 Histologically, changes typical of different underlying conditions, including benign epidermal J AM ACAD DERMATOL hyperplasia, warts, keratoacanthoma, hemangioma, and in situ or invasive carcinomas (SCC or verrucous carcinoma), may be observed. 223,225,[227][228][229] The coexistence of a benign penile horn and SCC on different areas of the glans has been described. 230 Surgical excision with careful microscopic examination of the base, followed by periodical control evaluations in case of malignancy, is strongly recommended, since at least one-third of these lesions may reveal an SCC at histologic observation.…”