Hemangiopericytoma of the Orbit Treated With Conservative Surgery and Radiotherapy

Setzkorn, Ronald K.; Lee, Ding Jen; Iliff, Nicholas T.; Green, W. Richard

doi:10.1001/archopht.1987.01060080105037

Cited by 23 publications

(12 citation statements)

References 26 publications

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“…Setzkorn et al reported two recurrences, which were treated surgically, with the third relapse treated by radiotherapy. The patient was still disease free 78 months after radiotherapy and experienced no side effects [9]. Due to the rarity of HPC in the orbit, radiotherapy is used in the case of recurrence [9,11].…”

Section: Discussionsupporting

confidence: 43%

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Solitary Fibrous Tumour of the Lacrimal Gland with Apparent hemangiopericytoma – Like Characteristics: A Case Study

Lešták¹

2014

J Clin Exp Ophthalmol

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Hemangiopericytoma (HPC) is a rare tumor originating from the mesenchyme. We will describe the clinical presentations, radiological and operative findings, and pathological features of a patient with lacrimal gland HPC. The patient was a 26-year-old female who presented with swelling of the left upper eye lid progressing over the past 12 months. On ophthalmological examination, no visual impairment was detected, but induration of the left eye was found in the area of the lacrimal gland. Orbital magnetic resonance imaging showed tumorous mass, of size 20 × 8 × 22 mm affecting the lacrimal gland. The patient underwent an anterior orbitotomy, which removed the palpebral portion of the lacrimal gland. Histology did not clarify the diagnosis. Three months after surgery, the tumor size had increased. MRI showed progression of the findings. It was therefore decided to perform a lateral orbitotomy with radical extirpation of the tumor. The morphology of the tumor, including positivity of the immunohistochemical marker CD34, showed predominant characteristics of the HPC. The patient has been subject to a follow-up for the past 84 months and no signs of recurrence or metastases were observed during this period.

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Section: Discussionsupporting

confidence: 43%

“…Surgical removal may be associated with an exenteration of the orbit [8] or radical excision of the tumor [9]. Pihlblad and Schaefer described the elimination of the tumor using embolization and subsequent extirpation after biopsy confirmation of HPC [10].…”

Section: Discussionsupporting

confidence: 40%

Solitary Fibrous Tumour of the Lacrimal Gland with Apparent hemangiopericytoma – Like Characteristics: A Case Study

Lešták¹

2014

J Clin Exp Ophthalmol

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“…Therefore, complete surgical removal should be performed regardless of the pathological findings. Occasionally, radiotherapy is used when the lesion is not completely removed [15]. Complete surgical removal was not possible in case 1, a patient with SFT, due to infiltration of the surrounding tissue, or in case 6, a patient with HPC, due to the fragile structure of the tumour.…”

Section: Discussionmentioning

confidence: 99%

CD34 + tumours of the orbit including solitary fibrous tumours: a six-case series

Jung¹,

Paik

Park

et al. 2017

BMC Ophthalmol

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BackgroundTo report six cases of CD34+ fibroblastic mesenchymal tumours, which are uncommon neoplasms in the orbit.Case presentationSix patients presenting with proptosis and palpable mass who were later diagnosed with fibrous solitary tumours, fibrous histocytoma or haemangiopericytoma in the orbit were included. All patients received radiologic examinations and surgical excision for histopathology and immunohistochemistry examinations. Five patients had no recurrence after a minimum follow-up of 12 months. One patient (case 6) experienced recurrence twice, and had debulking surgeries each time. At present, the patient still has remnant tumour in the orbit, but no growth has been detected during the past two years. The tumour size will be closely monitored.ConclusionsEven though fibroblastic tumours are rarely found in the orbit, they can present as a palpable mass with proptosis. Complete surgical excision is important for long-term prognosis, and immunohistochemical study is helpful for confirming pathologic diagnosis.

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“…Henderson & Farrow [1] do not believe radiotherapy should be used for orbital hemangiopericytomas except for palliative reasons. However, Setzkorn et al [5] treated a patient with a recurrent hemangiopericytoma by excision followed by radiotherapy, and 7 89 years later there was no sign of disease. The study performed by Mira et al showed a satisfactory response in 11 patients treated by radiotherapy [6].…”

Section: Discussionmentioning

confidence: 43%

Recurrent hemangiopericytoma and brachytherapy

1992

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Hemangiopericytoma of the Orbit Treated With Conservative Surgery and Radiotherapy

Cited by 23 publications

References 26 publications

Solitary Fibrous Tumour of the Lacrimal Gland with Apparent hemangiopericytoma – Like Characteristics: A Case Study

Solitary Fibrous Tumour of the Lacrimal Gland with Apparent hemangiopericytoma – Like Characteristics: A Case Study

CD34 + tumours of the orbit including solitary fibrous tumours: a six-case series

Recurrent hemangiopericytoma and brachytherapy

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