Hemato-biochemical and therapeutic studies on Escherichia coli associated with concurrent enteric infection in lambs

Abstract

Aim: The trials were designed on 30 lambs of age below 2 weeks exhibiting the symptoms of colibacillosis. Materials and Methods:Isolation of organism and identification of pathogenic Escherichia coli was confirmed by standard cultural, microbiological, serological, and biochemical tests. Venous blood was collected aseptically for hematological studies.Result: Bacteriological examinations of fecal sample were positive for E.coli and isolates identified on the basis of morphological, cultural, and biochemical characteristics provided further confirmation. Hematological indices recorded significant (p > 0.05) increase in the packed cell volume, total leucocyte count, lymphocyte, and neutrophil percentage, whereas biochemical indices recorded significant decrease in the serum glucose, protein and serum albumin/ globulin levels. Treatment regimen in four different groups, suggested, gentamicin and ciprofloxacin effective drugs followed by neomycin and co-trimoxazole. Conclusion:Study suggested significant (P > 0.05) alteration in hemato-biochemical parameters whereas results indicated gentamicin and ciprofloxacin as most effective drugs.

Comprehensive haemato-biochemical profiling in sheep affected by diarrhea: Insights into physiological impact and veterinary management

“…Increase in Hb, PCV and TEC is due to dehydration and hemoconcentration which occur invariably in cases of diarrhea as fluid volume is lost from body so relative count increases. Absolute leucocytic count in diarrhoeic sheep revealed significant leucocytosis due to neutrophilia, lymphocytosis, monocytosis and eosinophilia were in unison with the previous observation of Hassen et al (2013) [5] ; Ahmed (2020) [2] and Tarunpreet et al (2019) [13] . Increased TLC might be due to reaction of body defence mechanism against infection and also due to dehydration and hemoconcentration as reported by Hassen et al (2013) [5] .…”

“…Absolute leucocytic count in diarrhoeic sheep revealed significant leucocytosis due to neutrophilia, lymphocytosis, monocytosis and eosinophilia were in unison with the previous observation of Hassen et al (2013) [5] ; Ahmed (2020) [2] and Tarunpreet et al (2019) [13] . Increased TLC might be due to reaction of body defence mechanism against infection and also due to dehydration and hemoconcentration as reported by Hassen et al (2013) [5] . Serum biochemical profiles of diarrhoeic sheep/lambs in present study were significant decrease in values of total protein, serum globulin and serum albumin where as significant increase in the albumin: globulin ratio.…”

Antioxidant potential of coenzyme Q10 in Escherichia coli associated calf diarrhea

“…The reduction of TLC indicates effective antibacterial therapy. Similar findings were also recorded in other antimicrobial therapies in E. coli diarrhea in lamb (Hassan et al 2013). The reduction of fecal consistency score and dehydration (%) in post treatment period in diarrheic calves either by ST or by ST-CoQ10 indicated clinical recovery of animal from diarrhea.…”

Changes in Hematological and Biochemical Parameters of Periparturient Murrah Buffaloes during Summer and Winter Season: A Study to Assess Seasonal and Transitional Stress

“…In the present study, the TLC in all the weeks of transition period and control did not differ significantly in between summer and winter. In support to the present findings Aengwanich et al (2011) in cattle and Hassan et al (2013) in goats also reported the same. The lack of significant difference between the seasons under study might be attributed to the adaptation of the species to the increasing THI during summer season (Hassan et al 2013).…”