Hematological and Biochemical Changes in Mangalarga Marchador Horses After a Four-Beat Gait Challenge in Three Different Distances

Wanderley, Erika Korinfsky; Cavalcante, Bruno da Silva; Mélo, Stephânia Katurchi Mendes; Gonzalez, Julianne Cortizo; Manso, Helena Emília Cavalcanti da Costa Cordeiro; Filho, Hélio Cordeiro Manso

doi:10.1016/j.jevs.2015.01.009

Cited by 20 publications

(13 citation statements)

References 26 publications

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“…The increased activity of AST and ALT in serum of horses is directly related to a violation of the permeability of the muscle cell membranes, it can be registered in case of myopathy during physical activity. However, the enzymes activity in the horses' blood depends on the level of physical preparation, intensity and duration of the load (Wanderley et al, 2015).…”

Section: Resultsmentioning

confidence: 99%

Metabolic responses in endurance horses at exhausted syndrome

Maksymovych

Slivinska

2018

Ukr. Jour. of Vet. and Agr. Sci.

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The article shows the results of the study of biochemical blood indices in sports horses. It is shown that in horses after exercise developing the metabolic syndrome which is a result of insufficient supply of organs and tissues of energy accompanied by development of dehydration, cytolysis syndrome, uremic syndrome, electrolyte imbalance. Evaluation of cardiac output in horses must be performed during and after physical exertion, when during latent disease manifests itself clinically. It is important to know the ways of flowing the course of metabolic processes that occur in the body of horses during physical activity of varying intensity. The most common reason for excluding horses from sports events is metabolic disorders and cardiovascular dysfunction. The aim of the work was to investigate changes in biochemical blood parameters in sports horses after physical exertion. The material for research was horses, which are used in classical equestrian sports. In all horses the general analysis and biochemical parameters of blood, characterizing the functional state of the organs (heart, liver, kidneys) were investigated. The most frequent in horses for physical overstrain is registered increased fatigue, dyspnea, tachycardia, less frequent arrhythmias. In sports horses after exercise develops dehydration (hyperproteinemia), uremic syndrome (increasing the concentration of urea and creatinine), cytolysis syndrome (activity increase of AST and ALT), electrolyte imbalance (decrease in serum sodium and potassium). Hyperlactatemia that occurs in horses during exercise causes changes in the permeability of cardiomyocytes and exit enzymes in the blood and can play a key role in the pathogenesis of myocardial dystrophy. Installed tests can serve for early diagnosis of metabolic syndrome in horses for exercise.

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Section: Resultsmentioning

confidence: 99%

Metabolic responses in endurance horses at exhausted syndrome

Maksymovych

Slivinska

2018

Ukr. Jour. of Vet. and Agr. Sci.

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“…However, the enzymes activity in the horses' blood depends on the level of physical preparation, intensity and duration of the load [36].…”

Section: Resultsmentioning

confidence: 99%

Metabolic syndrome of horses during physical activity (diagnostics criteria)

Maksymovych¹,

Slivinska²

2017

Bìol. Tvarin

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“…Гіперферментемія АсАТ пов'язана з порушенням проникності мембран м'язових клітин (Wanderley et al, 2015). Не виключено, що підвищення активності АсАТ в сироватці крові коней після навантаження є результатом елімінації ферменту з кардіоміоцитів внаслідок їх пошкодження за МКД (Singh et al, 2011).…”

Section: результати та їх обговоренняunclassified

Cardiac enzymes activity and lactate concentration in the blood of sport horses at myocardial dystrophy

Slivinska

Maksymovych

Tkachenko³

et al. 2018

SMLNUVMB

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The article presents the results of research on the activity of cardiac specific enzymes and the concentration of lactate in the blood of sport horses for myocardial dystrophy of physical activity. Materials for researches were horses, used in the classical forms of equestrian sport of Ukrainian riding (n = 20), Hanoverian (n = 15) and Westphalian (n = 15) breeds. The average age of horses was 8.4 ± 0.71 years (3.5–16.0 g.), weight – 479.4 ± 8.54 kg (350–605 kg). Studies were conducted immediately before and immediately after exercise. The duration of regular training of average intensity was 1 hour: step 5 min; roaring lynx 10 minutes; step 5 min; training lynx 10 minutes; step 10 min; gallop with a transition to a step of 10 minutes; step 10 min. Blood samples from horses were taken from a jugular vein in a test tube without an anticoagulant (10 ml; Vacutest, Italy) and an anticoagulant (EDTA-K, 2.0 ml; Sarstedt, Germany). Diseases of the heart muscle are accompanied by the release of substances released from damaged cardiomyocytes, in particular, creatine kinase (CK), lactate dehydrogenase (LDH), myoglobin. It has been established that the key to the pathogenesis of myocardial dystrophy in sport horses is the discrepancy between costs and energy recovery in the functioning structures of the heart muscle due to excessive cardiac load and significant increase in energy costs, as well as a disturbance in the balance of the electrolytes. Hyperlactatemia that occurs in horses during exercise causes changes in the permeability of cardiomyocytes and exit enzymes in the blood and can play a key role in the pathogenesis of myocardial dystrophy. Іn sporting horses, after activity in blood serum, activity of AST and LDH increases in blood serum, a tendency to increase activity of creatine kinase (CК) is observed. The cardiac isoenzyme CK (CK‒MB) was detected by a specific marker of myocardial dystrophy in sport horses, since its activity was likely to increase in the blood of all experimental groups of animals. A less specific marker of myocardial damage was the activity of hydroxybutyrate dehydrogenase (LDH‒1) in the blood, since the probable difference was established only in the Westphalian horses. Investigating the activity of AST, CK and CK-MB in horses can serve for differential diagnosis of rhabdomyolysis syndrome and damage to heart muscle cells, in particular for myocardial dystrophy.

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Hematological and Biochemical Changes in Mangalarga Marchador Horses After a Four-Beat Gait Challenge in Three Different Distances

Cited by 20 publications

References 26 publications

Metabolic responses in endurance horses at exhausted syndrome

Metabolic responses in endurance horses at exhausted syndrome

Metabolic syndrome of horses during physical activity (diagnostics criteria)

Cardiac enzymes activity and lactate concentration in the blood of sport horses at myocardial dystrophy

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